Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 1 |
| GeneSet | KERLEY_RESPONSE_TO_CISPLATIN_UP |
| Enrichment Score (ES) | 0.5740307 |
| Normalized Enrichment Score (NES) | 1.7065283 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.9761587 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 127 | 0.840 | 0.0597 | Yes |
| 2 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 234 | 0.720 | 0.1110 | Yes |
| 3 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 300 | 0.668 | 0.1605 | Yes |
| 4 | INPP5D | INPP5D Entrez, Source | inositol polyphosphate-5-phosphatase, 145kDa | 466 | 0.565 | 0.1962 | Yes |
| 5 | FAS | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 533 | 0.537 | 0.2352 | Yes |
| 6 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 612 | 0.507 | 0.2711 | Yes |
| 7 | PDE4A | PDE4A Entrez, Source | phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) | 702 | 0.478 | 0.3042 | Yes |
| 8 | ZMAT3 | ZMAT3 Entrez, Source | zinc finger, matrin type 3 | 814 | 0.447 | 0.3335 | Yes |
| 9 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 853 | 0.437 | 0.3661 | Yes |
| 10 | PLK3 | PLK3 Entrez, Source | polo-like kinase 3 (Drosophila) | 926 | 0.419 | 0.3954 | Yes |
| 11 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 992 | 0.400 | 0.4236 | Yes |
| 12 | PHLDA3 | PHLDA3 Entrez, Source | pleckstrin homology-like domain, family A, member 3 | 995 | 0.400 | 0.4553 | Yes |
| 13 | TRIM22 | TRIM22 Entrez, Source | tripartite motif-containing 22 | 1028 | 0.394 | 0.4849 | Yes |
| 14 | SESN1 | SESN1 Entrez, Source | sestrin 1 | 1131 | 0.371 | 0.5087 | Yes |
| 15 | DRAM1 | 1196 | 0.354 | 0.5333 | Yes | ||
| 16 | CXCL14 | CXCL14 Entrez, Source | chemokine (C-X-C motif) ligand 14 | 1913 | 0.253 | 0.5138 | Yes |
| 17 | RPS27L | RPS27L Entrez, Source | ribosomal protein S27-like | 1934 | 0.251 | 0.5326 | Yes |
| 18 | FDXR | FDXR Entrez, Source | ferredoxin reductase | 1937 | 0.250 | 0.5524 | Yes |
| 19 | DDB2 | DDB2 Entrez, Source | damage-specific DNA binding protein 2, 48kDa | 2079 | 0.235 | 0.5632 | Yes |
| 20 | TNFRSF10C | TNFRSF10C Entrez, Source | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | 2205 | 0.223 | 0.5740 | Yes |
| 21 | DGKA | DGKA Entrez, Source | diacylglycerol kinase, alpha 80kDa | 3080 | 0.154 | 0.5378 | No |
| 22 | PPM1D | PPM1D Entrez, Source | protein phosphatase 1D magnesium-dependent, delta isoform | 3630 | 0.125 | 0.5174 | No |
| 23 | STK17A | STK17A Entrez, Source | serine/threonine kinase 17a (apoptosis-inducing) | 4945 | 0.079 | 0.4509 | No |
| 24 | FADS3 | FADS3 Entrez, Source | fatty acid desaturase 3 | 5000 | 0.078 | 0.4541 | No |
| 25 | ISYNA1 | ISYNA1 Entrez, Source | - | 5426 | 0.068 | 0.4360 | No |
| 26 | TP53TG1 | 5880 | 0.058 | 0.4155 | No | ||
| 27 | PROCR | PROCR Entrez, Source | protein C receptor, endothelial (EPCR) | 7544 | 0.028 | 0.3257 | No |
| 28 | LMNA | LMNA Entrez, Source | lamin A/C | 8959 | 0.008 | 0.2480 | No |
| 29 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 10013 | -0.008 | 0.1903 | No |
| 30 | GLS2 | GLS2 Entrez, Source | glutaminase 2 (liver, mitochondrial) | 11380 | -0.031 | 0.1171 | No |
| 31 | EPS8L2 | EPS8L2 Entrez, Source | EPS8-like 2 | 11600 | -0.035 | 0.1078 | No |
| 32 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 12952 | -0.070 | 0.0386 | No |
| 33 | PLK2 | PLK2 Entrez, Source | polo-like kinase 2 (Drosophila) | 14061 | -0.118 | -0.0134 | No |
| 34 | ANK1 | ANK1 Entrez, Source | ankyrin 1, erythrocytic | 14073 | -0.119 | -0.0046 | No |
| 35 | CAV1 | CAV1 Entrez, Source | caveolin 1, caveolae protein, 22kDa | 15622 | -0.232 | -0.0719 | No |
| 36 | IER3 | IER3 Entrez, Source | immediate early response 3 | 16272 | -0.312 | -0.0831 | No |
| 37 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 16387 | -0.329 | -0.0633 | No |
| 38 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 16752 | -0.395 | -0.0520 | No |
| 39 | ALDH1A3 | ALDH1A3 Entrez, Source | aldehyde dehydrogenase 1 family, member A3 | 16882 | -0.427 | -0.0252 | No |
| 40 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 17205 | -0.507 | -0.0028 | No |
| 41 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 17580 | -0.658 | 0.0287 | No |
