Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 1 |
| GeneSet | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES |
| Enrichment Score (ES) | 0.70438373 |
| Normalized Enrichment Score (NES) | 1.6682289 |
| Nominal p-value | 0.011655011 |
| FDR q-value | 0.9339196 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HLA-DPA1 | HLA-DPA1 Entrez, Source | major histocompatibility complex, class II, DP alpha 1 | 19 | 1.294 | 0.3586 | Yes |
| 2 | HLA-DPB1 | HLA-DPB1 Entrez, Source | major histocompatibility complex, class II, DP beta 1 | 567 | 0.521 | 0.4730 | Yes |
| 3 | HLA-DRB1 | HLA-DRB1 Entrez, Source | major histocompatibility complex, class II, DR beta 1 | 688 | 0.483 | 0.6007 | Yes |
| 4 | CD4 | CD4 Entrez, Source | CD4 molecule | 923 | 0.420 | 0.7044 | Yes |
| 5 | WAS | WAS Entrez, Source | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 2691 | 0.181 | 0.6569 | No |
| 6 | EVL | EVL Entrez, Source | Enah/Vasp-like | 5080 | 0.076 | 0.5460 | No |
| 7 | PLCG1 | PLCG1 Entrez, Source | phospholipase C, gamma 1 | 6218 | 0.051 | 0.4973 | No |
| 8 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 8923 | 0.008 | 0.3500 | No |
| 9 | ENAH | ENAH Entrez, Source | enabled homolog (Drosophila) | 10019 | -0.008 | 0.2916 | No |
| 10 | LCK | LCK Entrez, Source | lymphocyte-specific protein tyrosine kinase | 10049 | -0.008 | 0.2923 | No |
| 11 | VASP | VASP Entrez, Source | vasodilator-stimulated phosphoprotein | 10518 | -0.016 | 0.2708 | No |
| 12 | NCK1 | NCK1 Entrez, Source | NCK adaptor protein 1 | 10850 | -0.021 | 0.2584 | No |
| 13 | PAK2 | PAK2 Entrez, Source | p21 (CDKN1A)-activated kinase 2 | 13368 | -0.085 | 0.1429 | No |
| 14 | CD247 | CD247 Entrez, Source | CD247 molecule | 15230 | -0.197 | 0.0946 | No |
| 15 | HLA-DRB5 | HLA-DRB5 Entrez, Source | major histocompatibility complex, class II, DR beta 5 | 15606 | -0.230 | 0.1378 | No |
