Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 0 |
| GeneSet | REACTOME_MEIOTIC_SYNAPSIS |
| Enrichment Score (ES) | -0.66930944 |
| Normalized Enrichment Score (NES) | -1.8529311 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.06663173 |
| FWER p-Value | 0.613 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HIST2H2AC | HIST2H2AC Entrez, Source | histone cluster 2, H2ac | 664 | 0.491 | 0.0032 | No |
| 2 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 914 | 0.421 | 0.0236 | No |
| 3 | SYNE1 | SYNE1 Entrez, Source | spectrin repeat containing, nuclear envelope 1 | 2106 | 0.233 | -0.0234 | No |
| 4 | TINF2 | TINF2 Entrez, Source | TERF1 (TRF1)-interacting nuclear factor 2 | 4925 | 0.080 | -0.1730 | No |
| 5 | ATR | ATR Entrez, Source | ataxia telangiectasia and Rad3 related | 4932 | 0.080 | -0.1668 | No |
| 6 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 5715 | 0.061 | -0.2051 | No |
| 7 | TERF2 | TERF2 Entrez, Source | telomeric repeat binding factor 2 | 6520 | 0.045 | -0.2460 | No |
| 8 | SMC1A | SMC1A Entrez, Source | structural maintenance of chromosomes 1A | 6991 | 0.037 | -0.2690 | No |
| 9 | HSPA2 | HSPA2 Entrez, Source | heat shock 70kDa protein 2 | 7546 | 0.028 | -0.2974 | No |
| 10 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 8010 | 0.021 | -0.3213 | No |
| 11 | SMC1B | SMC1B Entrez, Source | structural maintenance of chromosomes 1B | 8700 | 0.011 | -0.3585 | No |
| 12 | LMNA | LMNA Entrez, Source | lamin A/C | 8959 | 0.008 | -0.3722 | No |
| 13 | REC8 | 8974 | 0.007 | -0.3724 | No | ||
| 14 | SYNE2 | SYNE2 Entrez, Source | spectrin repeat containing, nuclear envelope 2 | 9036 | 0.006 | -0.3752 | No |
| 15 | HIST1H4E | HIST1H4E Entrez, Source | histone cluster 1, H4e | 9219 | 0.004 | -0.3850 | No |
| 16 | STAG1 | STAG1 Entrez, Source | stromal antigen 1 | 9241 | 0.003 | -0.3859 | No |
| 17 | UBE2I | UBE2I Entrez, Source | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 9488 | 0.000 | -0.3995 | No |
| 18 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 9527 | -0.000 | -0.4016 | No |
| 19 | ACD | ACD Entrez, Source | adrenocortical dysplasia homolog (mouse) | 9862 | -0.005 | -0.4197 | No |
| 20 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 9986 | -0.007 | -0.4259 | No |
| 21 | STAG3 | STAG3 Entrez, Source | stromal antigen 3 | 10141 | -0.010 | -0.4337 | No |
| 22 | SUN2 | 11143 | -0.027 | -0.4869 | No | ||
| 23 | POT1 | POT1 Entrez, Source | POT1 protection of telomeres 1 homolog (S. pombe) | 11296 | -0.030 | -0.4929 | No |
| 24 | SMC3 | SMC3 Entrez, Source | structural maintenance of chromosomes 3 | 11562 | -0.035 | -0.5048 | No |
| 25 | RAD21 | RAD21 Entrez, Source | RAD21 homolog (S. pombe) | 11708 | -0.038 | -0.5098 | No |
| 26 | HIST1H4H | HIST1H4H Entrez, Source | histone cluster 1, H4h | 12125 | -0.047 | -0.5290 | No |
| 27 | DIDO1 | DIDO1 Entrez, Source | death inducer-obliterator 1 | 12452 | -0.055 | -0.5425 | No |
| 28 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 12870 | -0.068 | -0.5601 | No |
| 29 | STAG2 | STAG2 Entrez, Source | stromal antigen 2 | 13149 | -0.077 | -0.5693 | No |
| 30 | HIST1H2BH | HIST1H2BH Entrez, Source | histone cluster 1, H2bh | 13597 | -0.094 | -0.5863 | No |
| 31 | HIST1H2BE | HIST1H2BE Entrez, Source | histone cluster 1, H2be | 13611 | -0.095 | -0.5793 | No |
| 32 | HIST1H2AE | HIST1H2AE Entrez, Source | histone cluster 1, H2ae | 14163 | -0.124 | -0.5998 | No |
| 33 | TERF2IP | TERF2IP Entrez, Source | telomeric repeat binding factor 2, interacting protein | 14460 | -0.141 | -0.6047 | No |
| 34 | HIST1H2BG | HIST1H2BG Entrez, Source | histone cluster 1, H2bg | 15373 | -0.209 | -0.6382 | No |
| 35 | HIST1H2BC | HIST1H2BC Entrez, Source | histone cluster 1, H2bc | 15812 | -0.254 | -0.6419 | Yes |
| 36 | HIST2H2BE | HIST2H2BE Entrez, Source | histone cluster 2, H2be | 16216 | -0.303 | -0.6396 | Yes |
| 37 | HIST4H4 | HIST4H4 Entrez, Source | histone cluster 4, H4 | 16754 | -0.396 | -0.6371 | Yes |
| 38 | SYCP1 | SYCP1 Entrez, Source | synaptonemal complex protein 1 | 16806 | -0.407 | -0.6068 | Yes |
| 39 | HIST1H2BD | HIST1H2BD Entrez, Source | histone cluster 1, H2bd | 16826 | -0.413 | -0.5742 | Yes |
| 40 | HIST1H2BK | HIST1H2BK Entrez, Source | histone cluster 1, H2bk | 16932 | -0.436 | -0.5445 | Yes |
| 41 | HIST1H2AC | HIST1H2AC Entrez, Source | histone cluster 1, H2ac | 17773 | -0.774 | -0.5281 | Yes |
| 42 | SYCP2 | SYCP2 Entrez, Source | synaptonemal complex protein 2 | 17819 | -0.818 | -0.4640 | Yes |
| 43 | HIST1H4I | HIST1H4I Entrez, Source | histone cluster 1, H4i | 17977 | -1.021 | -0.3896 | Yes |
| 44 | HIST3H2BB | HIST3H2BB Entrez, Source | histone cluster 3, H2bb | 18007 | -1.109 | -0.3009 | Yes |
| 45 | HIST1H2BO | HIST1H2BO Entrez, Source | histone cluster 1, H2bo | 18024 | -1.161 | -0.2073 | Yes |
| 46 | HIST1H2BJ | HIST1H2BJ Entrez, Source | histone cluster 1, H2bj | 18062 | -1.272 | -0.1059 | Yes |
| 47 | HIST1H2BN | HIST1H2BN Entrez, Source | histone cluster 1, H2bn | 18071 | -1.326 | 0.0016 | Yes |
