Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 0 |
| GeneSet | REACTOME_RNA_POL_I_PROMOTER_OPENING |
| Enrichment Score (ES) | -0.74204725 |
| Normalized Enrichment Score (NES) | -1.9265115 |
| Nominal p-value | 0.0017123288 |
| FDR q-value | 0.04288368 |
| FWER p-Value | 0.185 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HIST2H2AC | HIST2H2AC Entrez, Source | histone cluster 2, H2ac | 664 | 0.491 | 0.0020 | No |
| 2 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 914 | 0.421 | 0.0213 | No |
| 3 | H3F3A | H3F3A Entrez, Source | H3 histone, family 3A | 3841 | 0.116 | -0.1315 | No |
| 4 | UBTF | UBTF Entrez, Source | upstream binding transcription factor, RNA polymerase I | 6205 | 0.051 | -0.2582 | No |
| 5 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 8010 | 0.021 | -0.3563 | No |
| 6 | H3F3B | H3F3B Entrez, Source | H3 histone, family 3B (H3.3B) | 8507 | 0.014 | -0.3827 | No |
| 7 | MBD2 | MBD2 Entrez, Source | methyl-CpG binding domain protein 2 | 8694 | 0.011 | -0.3921 | No |
| 8 | HIST1H4E | HIST1H4E Entrez, Source | histone cluster 1, H4e | 9219 | 0.004 | -0.4208 | No |
| 9 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 9986 | -0.007 | -0.4626 | No |
| 10 | HIST1H4H | HIST1H4H Entrez, Source | histone cluster 1, H4h | 12125 | -0.047 | -0.5772 | No |
| 11 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 13096 | -0.075 | -0.6250 | No |
| 12 | HIST1H2BH | HIST1H2BH Entrez, Source | histone cluster 1, H2bh | 13597 | -0.094 | -0.6452 | No |
| 13 | HIST1H2BE | HIST1H2BE Entrez, Source | histone cluster 1, H2be | 13611 | -0.095 | -0.6384 | No |
| 14 | HIST1H2AE | HIST1H2AE Entrez, Source | histone cluster 1, H2ae | 14163 | -0.124 | -0.6592 | No |
| 15 | HIST1H2BG | HIST1H2BG Entrez, Source | histone cluster 1, H2bg | 15373 | -0.209 | -0.7096 | No |
| 16 | HIST1H2BC | HIST1H2BC Entrez, Source | histone cluster 1, H2bc | 15812 | -0.254 | -0.7139 | Yes |
| 17 | HIST2H2BE | HIST2H2BE Entrez, Source | histone cluster 2, H2be | 16216 | -0.303 | -0.7123 | Yes |
| 18 | HIST4H4 | HIST4H4 Entrez, Source | histone cluster 4, H4 | 16754 | -0.396 | -0.7109 | Yes |
| 19 | HIST1H2BD | HIST1H2BD Entrez, Source | histone cluster 1, H2bd | 16826 | -0.413 | -0.6822 | Yes |
| 20 | HIST1H2BK | HIST1H2BK Entrez, Source | histone cluster 1, H2bk | 16932 | -0.436 | -0.6536 | Yes |
| 21 | HIST1H3E | HIST1H3E Entrez, Source | histone cluster 1, H3e | 17595 | -0.663 | -0.6380 | Yes |
| 22 | HIST1H2AC | HIST1H2AC Entrez, Source | histone cluster 1, H2ac | 17773 | -0.774 | -0.5868 | Yes |
| 23 | HIST1H3H | HIST1H3H Entrez, Source | histone cluster 1, H3h | 17882 | -0.890 | -0.5227 | Yes |
| 24 | HIST1H3G | HIST1H3G Entrez, Source | histone cluster 1, H3g | 17884 | -0.892 | -0.4524 | Yes |
| 25 | HIST1H4I | HIST1H4I Entrez, Source | histone cluster 1, H4i | 17977 | -1.021 | -0.3771 | Yes |
| 26 | HIST3H2BB | HIST3H2BB Entrez, Source | histone cluster 3, H2bb | 18007 | -1.109 | -0.2913 | Yes |
| 27 | HIST1H2BO | HIST1H2BO Entrez, Source | histone cluster 1, H2bo | 18024 | -1.161 | -0.2007 | Yes |
| 28 | HIST1H2BJ | HIST1H2BJ Entrez, Source | histone cluster 1, H2bj | 18062 | -1.272 | -0.1025 | Yes |
| 29 | HIST1H2BN | HIST1H2BN Entrez, Source | histone cluster 1, H2bn | 18071 | -1.326 | 0.0015 | Yes |
