Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 1 |
| GeneSet | WARTERS_IR_RESPONSE_5GY |
| Enrichment Score (ES) | 0.56128675 |
| Normalized Enrichment Score (NES) | 1.6499652 |
| Nominal p-value | 0.005167959 |
| FDR q-value | 0.95721895 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 127 | 0.840 | 0.0835 | Yes |
| 2 | POLH | POLH Entrez, Source | polymerase (DNA directed), eta | 179 | 0.768 | 0.1635 | Yes |
| 3 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 300 | 0.668 | 0.2288 | Yes |
| 4 | FAS | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 533 | 0.537 | 0.2739 | Yes |
| 5 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 612 | 0.507 | 0.3242 | Yes |
| 6 | TP53INP1 | TP53INP1 Entrez, Source | tumor protein p53 inducible nuclear protein 1 | 855 | 0.437 | 0.3578 | Yes |
| 7 | PLK3 | PLK3 Entrez, Source | polo-like kinase 3 (Drosophila) | 926 | 0.419 | 0.3991 | Yes |
| 8 | SESN1 | SESN1 Entrez, Source | sestrin 1 | 1131 | 0.371 | 0.4278 | Yes |
| 9 | WDR63 | WDR63 Entrez, Source | WD repeat domain 63 | 1565 | 0.295 | 0.4356 | Yes |
| 10 | BBC3 | BBC3 Entrez, Source | BCL2 binding component 3 | 1818 | 0.264 | 0.4502 | Yes |
| 11 | FDXR | FDXR Entrez, Source | ferredoxin reductase | 1937 | 0.250 | 0.4706 | Yes |
| 12 | VWCE | VWCE Entrez, Source | von Willebrand factor C and EGF domains | 2026 | 0.242 | 0.4918 | Yes |
| 13 | DDB2 | DDB2 Entrez, Source | damage-specific DNA binding protein 2, 48kDa | 2079 | 0.235 | 0.5143 | Yes |
| 14 | TNFRSF10C | TNFRSF10C Entrez, Source | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | 2205 | 0.223 | 0.5314 | Yes |
| 15 | HAS3 | HAS3 Entrez, Source | hyaluronan synthase 3 | 2496 | 0.195 | 0.5364 | Yes |
| 16 | PLCL2 | PLCL2 Entrez, Source | phospholipase C-like 2 | 2913 | 0.164 | 0.5310 | Yes |
| 17 | MDM2 | MDM2 Entrez, Source | Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) | 2982 | 0.159 | 0.5444 | Yes |
| 18 | NOTCH1 | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 3419 | 0.135 | 0.5349 | Yes |
| 19 | E2F7 | E2F7 Entrez, Source | E2F transcription factor 7 | 3574 | 0.127 | 0.5400 | Yes |
| 20 | PPM1D | PPM1D Entrez, Source | protein phosphatase 1D magnesium-dependent, delta isoform | 3630 | 0.125 | 0.5505 | Yes |
| 21 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 3939 | 0.112 | 0.5455 | Yes |
| 22 | NINJ1 | NINJ1 Entrez, Source | ninjurin 1 | 4009 | 0.109 | 0.5534 | Yes |
| 23 | CHADL | 4075 | 0.107 | 0.5613 | Yes | ||
| 24 | HSPA4L | HSPA4L Entrez, Source | heat shock 70kDa protein 4-like | 4963 | 0.079 | 0.5207 | No |
| 25 | FBXW7 | FBXW7 Entrez, Source | F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila) | 6007 | 0.056 | 0.4690 | No |
| 26 | FAM84B | FAM84B Entrez, Source | family with sequence similarity 84, member B | 6620 | 0.044 | 0.4398 | No |
| 27 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 10013 | -0.008 | 0.2529 | No |
| 28 | COQ9 | COQ9 Entrez, Source | coenzyme Q9 homolog (S. cerevisiae) | 10123 | -0.009 | 0.2478 | No |
| 29 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 10656 | -0.018 | 0.2203 | No |
| 30 | BLOC1S2 | BLOC1S2 Entrez, Source | biogenesis of lysosome-related organelles complex-1, subunit 2 | 11191 | -0.028 | 0.1938 | No |
| 31 | PHLDB3 | PHLDB3 Entrez, Source | pleckstrin homology-like domain, family B, member 3 | 12306 | -0.052 | 0.1377 | No |
| 32 | SH2D2A | SH2D2A Entrez, Source | SH2 domain protein 2A | 13675 | -0.098 | 0.0725 | No |
| 33 | THSD1 | THSD1 Entrez, Source | thrombospondin, type I, domain containing 1 | 15351 | -0.206 | 0.0020 | No |
| 34 | GDNF | GDNF Entrez, Source | glial cell derived neurotrophic factor | 16786 | -0.403 | -0.0339 | No |
| 35 | ZNF597 | ZNF597 Entrez, Source | zinc finger protein 597 | 17051 | -0.465 | 0.0016 | No |
| 36 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 17265 | -0.523 | 0.0462 | No |
