DatasetNS50719_832_collapsed_to_symbols.NS50719_832.cls
#arhinia_versus_control.NS50719_832.cls
#arhinia_versus_control_repos
PhenotypeNS50719_832.cls#arhinia_versus_control_repos
Upregulated in class1
GeneSetWARTERS_RESPONSE_TO_IR_SKIN
Enrichment Score (ES)0.6066623
Normalized Enrichment Score (NES)1.9454496
Nominal p-value0.0
FDR q-value0.15088971
FWER p-Value0.271
Table: GSEA Results Summary



Fig 1: Enrichment plot: WARTERS_RESPONSE_TO_IR_SKIN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CDKN1ACDKN1A
Entrez,  Source
cyclin-dependent kinase inhibitor 1A (p21, Cip1)1270.8400.0565Yes
2POLHPOLH
Entrez,  Source
polymerase (DNA directed), eta1790.7680.1119Yes
3BTG2BTG2
Entrez,  Source
BTG family, member 23000.6680.1558Yes
4FASFAS
Entrez,  Source
Fas (TNF receptor superfamily, member 6)5330.5370.1835Yes
5GDF15GDF15
Entrez,  Source
growth differentiation factor 156120.5070.2176Yes
6ZMAT3ZMAT3
Entrez,  Source
zinc finger, matrin type 38140.4470.2403Yes
7TP53INP1TP53INP1
Entrez,  Source
tumor protein p53 inducible nuclear protein 18550.4370.2711Yes
8TRIM22TRIM22
Entrez,  Source
tripartite motif-containing 2210280.3940.2914Yes
9ETV7ETV7
Entrez,  Source
ets variant gene 7 (TEL2 oncogene)10990.3780.3162Yes
10SESN1SESN1
Entrez,  Source
sestrin 111310.3710.3425Yes
11PAPPAPAPPA
Entrez,  Source
pregnancy-associated plasma protein A, pappalysin 111940.3550.3660Yes
12DRAM111960.3540.3927Yes
13WDR63WDR63
Entrez,  Source
WD repeat domain 6315650.2950.3947Yes
14ZNF79ZNF79
Entrez,  Source
zinc finger protein 7917660.2690.4039Yes
15RAD51CRAD51C
Entrez,  Source
RAD51 homolog C (S. cerevisiae)17730.2680.4238Yes
16DEPDC7DEPDC7
Entrez,  Source
DEP domain containing 717760.2670.4440Yes
17BBC3BBC3
Entrez,  Source
BCL2 binding component 318180.2640.4617Yes
18MICALL219070.2530.4760Yes
19RPS27LRPS27L
Entrez,  Source
ribosomal protein S27-like19340.2510.4935Yes
20FDXRFDXR
Entrez,  Source
ferredoxin reductase19370.2500.5124Yes
21VWCEVWCE
Entrez,  Source
von Willebrand factor C and EGF domains20260.2420.5258Yes
22DDB2DDB2
Entrez,  Source
damage-specific DNA binding protein 2, 48kDa20790.2350.5407Yes
23NEAT122010.2240.5509Yes
24TNFRSF10CTNFRSF10C
Entrez,  Source
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain22050.2230.5676Yes
25FGFBP325680.1900.5620Yes
26PLCL2PLCL2
Entrez,  Source
phospholipase C-like 229130.1640.5553Yes
27MDM2MDM2
Entrez,  Source
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)29820.1590.5636Yes
28TRIAP1TRIAP1
Entrez,  Source
TP53 regulated inhibitor of apoptosis 133700.1380.5526Yes
29ID3ID3
Entrez,  Source
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein34070.1350.5608Yes
30NOTCH1NOTCH1
Entrez,  Source
Notch homolog 1, translocation-associated (Drosophila)34190.1350.5704Yes
31FRMD4AFRMD4A
Entrez,  Source
FERM domain containing 4A35270.1290.5743Yes
32E2F7E2F7
Entrez,  Source
E2F transcription factor 735740.1270.5813Yes
33RRM2BRRM2B
Entrez,  Source
ribonucleotide reductase M2 B (TP53 inducible)35960.1260.5897Yes
34PPM1DPPM1D
Entrez,  Source
protein phosphatase 1D magnesium-dependent, delta isoform36300.1250.5974Yes
35GM2AGM2A
Entrez,  Source
GM2 ganglioside activator37100.1210.6022Yes
36FBXO22FBXO22
Entrez,  Source
F-box protein 2240070.1090.5940Yes
37NINJ1NINJ1
Entrez,  Source
ninjurin 140090.1090.6022Yes
38CHADL40750.1070.6067Yes
39BTG3BTG3
Entrez,  Source
BTG family, member 344720.0940.5918No
40ICAM5ICAM5
Entrez,  Source
intercellular adhesion molecule 5, telencephalin46370.0880.5894No
41CCNG1CCNG1
Entrez,  Source
cyclin G146430.0880.5958No
42HSPA4LHSPA4L
Entrez,  Source
heat shock 70kDa protein 4-like49630.0790.5841No
43CES2CES2
Entrez,  Source
carboxylesterase 2 (intestine, liver)52190.0730.5754No
44TP53TG158800.0580.5432No
45FBXW7FBXW7
Entrez,  Source
F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)60070.0560.5405No
46JAM3JAM3
Entrez,  Source
junctional adhesion molecule 370270.0370.4867No
47SCN9ASCN9A
Entrez,  Source
sodium channel, voltage-gated, type IX, alpha70570.0360.4879No
48ZNF219ZNF219
Entrez,  Source
zinc finger protein 21979210.0220.4417No
49TGFBITGFBI
Entrez,  Source
transforming growth factor, beta-induced, 68kDa80750.0200.4348No
50ASGR1ASGR1
Entrez,  Source
asialoglycoprotein receptor 186360.0120.4047No
51DNAJB4DNAJB4
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 487290.0110.4004No
52MAGT188320.0090.3954No
53RTTNRTTN
Entrez,  Source
rotatin88850.0090.3932No
54ALCAMALCAM
Entrez,  Source
activated leukocyte cell adhesion molecule10839-0.0210.2865No
55TMTC3TMTC3
Entrez,  Source
transmembrane and tetratricopeptide repeat containing 310845-0.0210.2879No
56BLOC1S2BLOC1S2
Entrez,  Source
biogenesis of lysosome-related organelles complex-1, subunit 211191-0.0280.2708No
57ANKRD33B11285-0.0290.2679No
58PPFIBP1PPFIBP1
Entrez,  Source
PTPRF interacting protein, binding protein 1 (liprin beta 1)11703-0.0380.2476No
59CABYRCABYR
Entrez,  Source
calcium binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)12012-0.0440.2339No
60ANKRA2ANKRA2
Entrez,  Source
ankyrin repeat, family A (RFXANK-like), 213666-0.0980.1497No
61THSD1THSD1
Entrez,  Source
thrombospondin, type I, domain containing 115351-0.2060.0719No
62SNHG8SNHG8
Entrez,  Source
small nucleolar RNA host gene (non-protein coding) 815727-0.2430.0695No
63NODALNODAL
Entrez,  Source
nodal homolog (mouse)16563-0.3580.0503No
64COMPCOMP
Entrez,  Source
cartilage oligomeric matrix protein17029-0.4590.0593No
Table: GSEA details [plain text format]



Fig 2: WARTERS_RESPONSE_TO_IR_SKIN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: WARTERS_RESPONSE_TO_IR_SKIN: Random ES distribution   
Gene set null distribution of ES for WARTERS_RESPONSE_TO_IR_SKIN