Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_corrected2_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 0 |
| GeneSet | BIOCARTA_CELLCYCLE_PATHWAY |
| Enrichment Score (ES) | -0.7202499 |
| Normalized Enrichment Score (NES) | -1.9898967 |
| Nominal p-value | 0.0044444446 |
| FDR q-value | 0.015280238 |
| FWER p-Value | 0.225 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 4728 | 0.360 | -0.1914 | No |
| 2 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 6446 | 0.201 | -0.2517 | No |
| 3 | CCNH | CCNH Entrez, Source | cyclin H | 7549 | 0.139 | -0.2890 | No |
| 4 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 7592 | 0.137 | -0.2730 | No |
| 5 | CDK1 | 10283 | 0.043 | -0.4034 | No | ||
| 6 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 10803 | 0.029 | -0.4258 | No |
| 7 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11314 | 0.015 | -0.4497 | No |
| 8 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 12340 | -0.010 | -0.5001 | No |
| 9 | RBL1 | RBL1 Entrez, Source | retinoblastoma-like 1 (p107) | 12787 | -0.021 | -0.5199 | No |
| 10 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 12812 | -0.022 | -0.5182 | No |
| 11 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 13421 | -0.038 | -0.5440 | No |
| 12 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 14226 | -0.061 | -0.5766 | No |
| 13 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 14329 | -0.063 | -0.5734 | No |
| 14 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 14962 | -0.085 | -0.5942 | No |
| 15 | TFDP1 | TFDP1 Entrez, Source | transcription factor Dp-1 | 15001 | -0.086 | -0.5847 | No |
| 16 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 15299 | -0.098 | -0.5867 | No |
| 17 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 16231 | -0.152 | -0.6137 | Yes |
| 18 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 16710 | -0.200 | -0.6113 | Yes |
| 19 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 18865 | -0.835 | -0.6097 | Yes |
| 20 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 19448 | -1.290 | -0.4683 | Yes |
| 21 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 19664 | -1.701 | -0.2540 | Yes |
| 22 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 19720 | -1.970 | 0.0040 | Yes |
