Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_corrected2_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 1 |
| GeneSet | BIOCARTA_HDAC_PATHWAY |
| Enrichment Score (ES) | 0.7030774 |
| Normalized Enrichment Score (NES) | 1.5743339 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CAMK1G | CAMK1G Entrez, Source | calcium/calmodulin-dependent protein kinase IG | 32 | 3.286 | 0.3110 | Yes |
| 2 | MEF2C | MEF2C Entrez, Source | MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) | 51 | 3.034 | 0.5986 | Yes |
| 3 | CAMK1 | CAMK1 Entrez, Source | calcium/calmodulin-dependent protein kinase I | 1205 | 1.235 | 0.6578 | Yes |
| 4 | NFATC2 | NFATC2 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 2034 | 0.916 | 0.7031 | Yes |
| 5 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 4994 | 0.330 | 0.5848 | No |
| 6 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 5820 | 0.247 | 0.5665 | No |
| 7 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 6766 | 0.179 | 0.5358 | No |
| 8 | NFATC1 | NFATC1 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | 7020 | 0.164 | 0.5387 | No |
| 9 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 7102 | 0.160 | 0.5498 | No |
| 10 | CABIN1 | CABIN1 Entrez, Source | - | 7708 | 0.131 | 0.5317 | No |
| 11 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 8569 | 0.095 | 0.4973 | No |
| 12 | HDAC5 | HDAC5 Entrez, Source | histone deacetylase 5 | 9445 | 0.066 | 0.4593 | No |
| 13 | MEF2D | MEF2D Entrez, Source | MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) | 9569 | 0.063 | 0.4591 | No |
| 14 | CALM3 | CALM3 Entrez, Source | calmodulin 3 (phosphorylase kinase, delta) | 10163 | 0.046 | 0.4335 | No |
| 15 | PPP3CB | PPP3CB Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) | 10524 | 0.036 | 0.4187 | No |
| 16 | MEF2A | MEF2A Entrez, Source | MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) | 10644 | 0.033 | 0.4158 | No |
| 17 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 12498 | -0.014 | 0.3234 | No |
| 18 | PPP3CC | PPP3CC Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) | 12580 | -0.016 | 0.3209 | No |
| 19 | INSR | INSR Entrez, Source | insulin receptor | 13235 | -0.032 | 0.2909 | No |
| 20 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 13456 | -0.039 | 0.2834 | No |
| 21 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 14698 | -0.075 | 0.2278 | No |
| 22 | CALM1 | CALM1 Entrez, Source | calmodulin 1 (phosphorylase kinase, delta) | 15059 | -0.089 | 0.2180 | No |
| 23 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 15493 | -0.108 | 0.2064 | No |
| 24 | MAPK7 | MAPK7 Entrez, Source | mitogen-activated protein kinase 7 | 15690 | -0.119 | 0.2078 | No |
