Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_corrected2_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 1 |
| GeneSet | GNF2_CYP2B6 |
| Enrichment Score (ES) | 0.6728115 |
| Normalized Enrichment Score (NES) | 1.5771492 |
| Nominal p-value | 0.0037128713 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CYP2C8 | CYP2C8 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 8 | 124 | 2.597 | 0.1256 | Yes |
| 2 | HGFAC | HGFAC Entrez, Source | HGF activator | 636 | 1.618 | 0.1819 | Yes |
| 3 | SERPINF2 | SERPINF2 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | 734 | 1.520 | 0.2541 | Yes |
| 4 | CYP2D6 | CYP2D6 Entrez, Source | cytochrome P450, family 2, subfamily D, polypeptide 6 | 1154 | 1.261 | 0.2970 | Yes |
| 5 | F12 | F12 Entrez, Source | coagulation factor XII (Hageman factor) | 1211 | 1.232 | 0.3567 | Yes |
| 6 | CES1 | CES1 Entrez, Source | carboxylesterase 1 (monocyte/macrophage serine esterase 1) | 1358 | 1.165 | 0.4085 | Yes |
| 7 | FCN3 | FCN3 Entrez, Source | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen) | 1527 | 1.110 | 0.4564 | Yes |
| 8 | ABCC6 | ABCC6 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 | 2123 | 0.890 | 0.4715 | Yes |
| 9 | CYP27A1 | CYP27A1 Entrez, Source | cytochrome P450, family 27, subfamily A, polypeptide 1 | 2191 | 0.871 | 0.5123 | Yes |
| 10 | MAT1A | MAT1A Entrez, Source | methionine adenosyltransferase I, alpha | 2414 | 0.812 | 0.5423 | Yes |
| 11 | GCHFR | GCHFR Entrez, Source | GTP cyclohydrolase I feedback regulator | 2566 | 0.767 | 0.5736 | Yes |
| 12 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 2840 | 0.692 | 0.5950 | Yes |
| 13 | HPN | HPN Entrez, Source | hepsin (transmembrane protease, serine 1) | 3059 | 0.642 | 0.6166 | Yes |
| 14 | LCAT | LCAT Entrez, Source | lecithin-cholesterol acyltransferase | 3414 | 0.571 | 0.6277 | Yes |
| 15 | HPX | HPX Entrez, Source | hemopexin | 3534 | 0.546 | 0.6494 | Yes |
| 16 | RDH16 | RDH16 Entrez, Source | retinol dehydrogenase 16 (all-trans) | 3940 | 0.469 | 0.6527 | Yes |
| 17 | ORM1 | ORM1 Entrez, Source | orosomucoid 1 | 4004 | 0.459 | 0.6728 | Yes |
| 18 | ORM2 | ORM2 Entrez, Source | orosomucoid 2 | 4856 | 0.344 | 0.6472 | No |
| 19 | TST | TST Entrez, Source | thiosulfate sulfurtransferase (rhodanese) | 6220 | 0.217 | 0.5893 | No |
| 20 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 7521 | 0.140 | 0.5306 | No |
| 21 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 9001 | 0.080 | 0.4599 | No |
| 22 | ANG | ANG Entrez, Source | angiogenin, ribonuclease, RNase A family, 5 | 9674 | 0.060 | 0.4289 | No |
| 23 | SERPING1 | SERPING1 Entrez, Source | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | 9817 | 0.056 | 0.4246 | No |
| 24 | PROC | PROC Entrez, Source | protein C (inactivator of coagulation factors Va and VIIIa) | 10820 | 0.028 | 0.3753 | No |
| 25 | DCXR | DCXR Entrez, Source | dicarbonyl/L-xylulose reductase | 10959 | 0.024 | 0.3696 | No |
| 26 | ASL | ASL Entrez, Source | argininosuccinate lyase | 10960 | 0.024 | 0.3708 | No |
| 27 | C8G | C8G Entrez, Source | complement component 8, gamma polypeptide | 13968 | -0.052 | 0.2214 | No |
| 28 | APOC1 | APOC1 Entrez, Source | apolipoprotein C-I | 15349 | -0.101 | 0.1567 | No |
| 29 | CYP2B6 | CYP2B6 Entrez, Source | cytochrome P450, family 2, subfamily B, polypeptide 6 | 17321 | -0.288 | 0.0716 | No |
| 30 | HSD17B6 | HSD17B6 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 6 | 17954 | -0.441 | 0.0621 | No |
| 31 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 18430 | -0.615 | 0.0692 | No |
