Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_corrected2_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 1 |
| GeneSet | GO_PHOTOTRANSDUCTION |
| Enrichment Score (ES) | 0.67003524 |
| Normalized Enrichment Score (NES) | 1.488905 |
| Nominal p-value | 0.016021362 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | AIPL1 | AIPL1 Entrez, Source | aryl hydrocarbon receptor interacting protein-like 1 | 26 | 3.433 | 0.2165 | Yes |
| 2 | TRPC3 | TRPC3 Entrez, Source | transient receptor potential cation channel, subfamily C, member 3 | 31 | 3.383 | 0.4310 | Yes |
| 3 | NR2E3 | NR2E3 Entrez, Source | nuclear receptor subfamily 2, group E, member 3 | 665 | 1.593 | 0.5000 | Yes |
| 4 | OPN1SW | OPN1SW Entrez, Source | opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) | 743 | 1.515 | 0.5923 | Yes |
| 5 | OPN3 | OPN3 Entrez, Source | opsin 3 (encephalopsin, panopsin) | 1355 | 1.166 | 0.6353 | Yes |
| 6 | PDE6C | PDE6C Entrez, Source | phosphodiesterase 6C, cGMP-specific, cone, alpha prime | 1892 | 0.974 | 0.6700 | Yes |
| 7 | PDE6B | PDE6B Entrez, Source | phosphodiesterase 6B, cGMP-specific, rod, beta (congenital stationary night blindness 3, autosomal dominant) | 3663 | 0.518 | 0.6134 | No |
| 8 | PLEKHB1 | PLEKHB1 Entrez, Source | pleckstrin homology domain containing, family B (evectins) member 1 | 4248 | 0.422 | 0.6107 | No |
| 9 | GNGT1 | GNGT1 Entrez, Source | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 5444 | 0.280 | 0.5680 | No |
| 10 | PDE6G | PDE6G Entrez, Source | phosphodiesterase 6G, cGMP-specific, rod, gamma | 5670 | 0.259 | 0.5731 | No |
| 11 | GUCA1A | GUCA1A Entrez, Source | guanylate cyclase activator 1A (retina) | 5989 | 0.233 | 0.5718 | No |
| 12 | CDS1 | CDS1 Entrez, Source | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 7106 | 0.160 | 0.5255 | No |
| 13 | GUCA1B | GUCA1B Entrez, Source | guanylate cyclase activator 1B (retina) | 7635 | 0.135 | 0.5074 | No |
| 14 | UNC119 | UNC119 Entrez, Source | unc-119 homolog (C. elegans) | 8303 | 0.106 | 0.4804 | No |
| 15 | GNGT2 | GNGT2 Entrez, Source | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 | 9489 | 0.065 | 0.4246 | No |
| 16 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 11216 | 0.017 | 0.3384 | No |
| 17 | PITPNM1 | PITPNM1 Entrez, Source | phosphatidylinositol transfer protein, membrane-associated 1 | 12741 | -0.020 | 0.2626 | No |
| 18 | RDH11 | RDH11 Entrez, Source | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 13935 | -0.051 | 0.2056 | No |
| 19 | GNB1 | GNB1 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 14230 | -0.061 | 0.1945 | No |
| 20 | GNA11 | GNA11 Entrez, Source | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 14590 | -0.071 | 0.1809 | No |
| 21 | CNGA1 | CNGA1 Entrez, Source | cyclic nucleotide gated channel alpha 1 | 17571 | -0.341 | 0.0519 | No |
| 22 | ARRB1 | ARRB1 Entrez, Source | arrestin, beta 1 | 17885 | -0.422 | 0.0628 | No |
| 23 | ABCA4 | ABCA4 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 4 | 18234 | -0.534 | 0.0791 | No |
