Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_corrected2_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 1 |
| GeneSet | GRADE_METASTASIS_DN |
| Enrichment Score (ES) | 0.69651735 |
| Normalized Enrichment Score (NES) | 1.7011136 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.43073168 |
| FWER p-Value | 0.799 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GSTM1 | GSTM1 Entrez, Source | glutathione S-transferase M1 | 0 | 5.000 | 0.4836 | Yes |
| 2 | FTCD | FTCD Entrez, Source | formiminotransferase cyclodeaminase | 194 | 2.303 | 0.6965 | Yes |
| 3 | MAP3K8 | MAP3K8 Entrez, Source | mitogen-activated protein kinase kinase kinase 8 | 2848 | 0.690 | 0.6290 | No |
| 4 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 7001 | 0.165 | 0.4349 | No |
| 5 | STAP2 | STAP2 Entrez, Source | - | 9331 | 0.070 | 0.3238 | No |
| 6 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 9432 | 0.067 | 0.3251 | No |
| 7 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 10770 | 0.030 | 0.2603 | No |
| 8 | TCF3 | TCF3 Entrez, Source | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 11492 | 0.011 | 0.2249 | No |
| 9 | OLA1 | 12033 | -0.003 | 0.1978 | No | ||
| 10 | NRBP1 | NRBP1 Entrez, Source | nuclear receptor binding protein 1 | 12426 | -0.012 | 0.1792 | No |
| 11 | UQCRC1 | UQCRC1 Entrez, Source | ubiquinol-cytochrome c reductase core protein I | 12699 | -0.019 | 0.1672 | No |
| 12 | USP9X | USP9X Entrez, Source | ubiquitin specific peptidase 9, X-linked | 12785 | -0.021 | 0.1650 | No |
| 13 | SNRPD2 | SNRPD2 Entrez, Source | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa | 12943 | -0.026 | 0.1595 | No |
| 14 | OAZ1 | OAZ1 Entrez, Source | ornithine decarboxylase antizyme 1 | 12956 | -0.026 | 0.1614 | No |
| 15 | AP2S1 | AP2S1 Entrez, Source | adaptor-related protein complex 2, sigma 1 subunit | 13065 | -0.028 | 0.1586 | No |
| 16 | PRMT1 | PRMT1 Entrez, Source | protein arginine methyltransferase 1 | 13304 | -0.035 | 0.1499 | No |
| 17 | TLE1 | TLE1 Entrez, Source | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 13318 | -0.035 | 0.1527 | No |
| 18 | PPP2R1A | PPP2R1A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 13331 | -0.036 | 0.1555 | No |
| 19 | ADAR | ADAR Entrez, Source | adenosine deaminase, RNA-specific | 13464 | -0.039 | 0.1526 | No |
| 20 | PMF1 | PMF1 Entrez, Source | polyamine-modulated factor 1 | 13540 | -0.041 | 0.1527 | No |
| 21 | ATP5J2 | ATP5J2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2 | 13788 | -0.047 | 0.1448 | No |
| 22 | TFG | TFG Entrez, Source | TRK-fused gene | 13820 | -0.048 | 0.1478 | No |
| 23 | CCT7 | CCT7 Entrez, Source | chaperonin containing TCP1, subunit 7 (eta) | 13825 | -0.048 | 0.1523 | No |
| 24 | EIF3I | 13826 | -0.048 | 0.1570 | No | ||
| 25 | PSMB4 | PSMB4 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 4 | 13883 | -0.050 | 0.1590 | No |
| 26 | NAA10 | 13906 | -0.050 | 0.1627 | No | ||
| 27 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 14122 | -0.057 | 0.1574 | No |
| 28 | YWHAG | YWHAG Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 14184 | -0.059 | 0.1600 | No |
| 29 | PPIB | PPIB Entrez, Source | peptidylprolyl isomerase B (cyclophilin B) | 14228 | -0.061 | 0.1637 | No |
| 30 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 14561 | -0.071 | 0.1538 | No |
| 31 | LRRC41 | LRRC41 Entrez, Source | leucine rich repeat containing 41 | 14661 | -0.073 | 0.1558 | No |
| 32 | PDCD11 | PDCD11 Entrez, Source | programmed cell death 11 | 14692 | -0.075 | 0.1615 | No |
| 33 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 14729 | -0.076 | 0.1671 | No |
| 34 | SSBP1 | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 14736 | -0.077 | 0.1742 | No |
| 35 | CLIC1 | CLIC1 Entrez, Source | chloride intracellular channel 1 | 15077 | -0.090 | 0.1657 | No |
| 36 | POLR2I | POLR2I Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 15364 | -0.101 | 0.1610 | No |
| 37 | CDCA3 | CDCA3 Entrez, Source | cell division cycle associated 3 | 15422 | -0.104 | 0.1682 | No |
| 38 | PDCD5 | PDCD5 Entrez, Source | programmed cell death 5 | 15579 | -0.113 | 0.1712 | No |
| 39 | ZNF37A | ZNF37A Entrez, Source | zinc finger protein 37A | 15649 | -0.117 | 0.1789 | No |
| 40 | PSMC4 | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 16126 | -0.144 | 0.1687 | No |
| 41 | PSMA6 | PSMA6 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 6 | 16522 | -0.177 | 0.1658 | No |
