Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_corrected2_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 0 |
| GeneSet | REACTOME_MEIOTIC_SYNAPSIS |
| Enrichment Score (ES) | -0.6959553 |
| Normalized Enrichment Score (NES) | -2.2228503 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.7471853E-4 |
| FWER p-Value | 0.002 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SMC1B | SMC1B Entrez, Source | structural maintenance of chromosomes 1B | 854 | 1.434 | 0.0125 | No |
| 2 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 4459 | 0.392 | -0.1547 | No |
| 3 | SYNE1 | SYNE1 Entrez, Source | spectrin repeat containing, nuclear envelope 1 | 5326 | 0.290 | -0.1873 | No |
| 4 | HIST1H4E | HIST1H4E Entrez, Source | histone cluster 1, H4e | 5438 | 0.280 | -0.1820 | No |
| 5 | ATR | ATR Entrez, Source | ataxia telangiectasia and Rad3 related | 6036 | 0.229 | -0.2033 | No |
| 6 | POT1 | POT1 Entrez, Source | POT1 protection of telomeres 1 homolog (S. pombe) | 6311 | 0.210 | -0.2090 | No |
| 7 | SYCP1 | SYCP1 Entrez, Source | synaptonemal complex protein 1 | 6392 | 0.205 | -0.2051 | No |
| 8 | HIST2H2AC | HIST2H2AC Entrez, Source | histone cluster 2, H2ac | 6531 | 0.194 | -0.2046 | No |
| 9 | STAG3 | STAG3 Entrez, Source | stromal antigen 3 | 6830 | 0.176 | -0.2128 | No |
| 10 | SUN2 | 6862 | 0.174 | -0.2076 | No | ||
| 11 | TINF2 | TINF2 Entrez, Source | TERF1 (TRF1)-interacting nuclear factor 2 | 7772 | 0.129 | -0.2487 | No |
| 12 | ACD | ACD Entrez, Source | adrenocortical dysplasia homolog (mouse) | 8620 | 0.094 | -0.2879 | No |
| 13 | TERF2IP | TERF2IP Entrez, Source | telomeric repeat binding factor 2, interacting protein | 8862 | 0.085 | -0.2968 | No |
| 14 | TERF2 | TERF2 Entrez, Source | telomeric repeat binding factor 2 | 9751 | 0.058 | -0.3395 | No |
| 15 | RAD21 | RAD21 Entrez, Source | RAD21 homolog (S. pombe) | 9827 | 0.056 | -0.3412 | No |
| 16 | SMC1A | SMC1A Entrez, Source | structural maintenance of chromosomes 1A | 11023 | 0.022 | -0.4008 | No |
| 17 | SYNE2 | SYNE2 Entrez, Source | spectrin repeat containing, nuclear envelope 2 | 12099 | -0.005 | -0.4550 | No |
| 18 | UBE2I | UBE2I Entrez, Source | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 12129 | -0.005 | -0.4563 | No |
| 19 | SMC3 | SMC3 Entrez, Source | structural maintenance of chromosomes 3 | 12703 | -0.019 | -0.4846 | No |
| 20 | HIST1H2BH | HIST1H2BH Entrez, Source | histone cluster 1, H2bh | 12717 | -0.019 | -0.4845 | No |
| 21 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 13443 | -0.038 | -0.5197 | No |
| 22 | HSPA2 | HSPA2 Entrez, Source | heat shock 70kDa protein 2 | 14430 | -0.066 | -0.5670 | No |
| 23 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 14498 | -0.069 | -0.5678 | No |
| 24 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 14561 | -0.071 | -0.5682 | No |
| 25 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 14710 | -0.076 | -0.5727 | No |
| 26 | STAG2 | STAG2 Entrez, Source | stromal antigen 2 | 14977 | -0.085 | -0.5829 | No |
| 27 | HIST2H2BE | HIST2H2BE Entrez, Source | histone cluster 2, H2be | 15708 | -0.119 | -0.6152 | No |
| 28 | DIDO1 | DIDO1 Entrez, Source | death inducer-obliterator 1 | 16306 | -0.159 | -0.6392 | No |
| 29 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 16468 | -0.172 | -0.6407 | No |
| 30 | STAG1 | STAG1 Entrez, Source | stromal antigen 1 | 16988 | -0.238 | -0.6578 | No |
| 31 | LMNA | LMNA Entrez, Source | lamin A/C | 17009 | -0.240 | -0.6494 | No |
| 32 | REC8 | 17041 | -0.244 | -0.6415 | No | ||
| 33 | HIST1H2BF | HIST1H2BF Entrez, Source | histone cluster 1, H2bf | 17743 | -0.382 | -0.6622 | No |
| 34 | HIST1H2BE | HIST1H2BE Entrez, Source | histone cluster 1, H2be | 18411 | -0.608 | -0.6724 | Yes |
| 35 | HIST1H2AC | HIST1H2AC Entrez, Source | histone cluster 1, H2ac | 18496 | -0.643 | -0.6516 | Yes |
| 36 | HIST3H2BB | HIST3H2BB Entrez, Source | histone cluster 3, H2bb | 18599 | -0.688 | -0.6300 | Yes |
| 37 | HIST4H4 | HIST4H4 Entrez, Source | histone cluster 4, H4 | 19052 | -0.943 | -0.6163 | Yes |
| 38 | SYCP2 | SYCP2 Entrez, Source | synaptonemal complex protein 2 | 19214 | -1.062 | -0.5831 | Yes |
| 39 | HIST1H2BO | HIST1H2BO Entrez, Source | histone cluster 1, H2bo | 19226 | -1.071 | -0.5421 | Yes |
| 40 | HIST1H2BJ | HIST1H2BJ Entrez, Source | histone cluster 1, H2bj | 19248 | -1.094 | -0.5006 | Yes |
| 41 | HIST1H2AE | HIST1H2AE Entrez, Source | histone cluster 1, H2ae | 19289 | -1.131 | -0.4587 | Yes |
| 42 | HIST1H2BN | HIST1H2BN Entrez, Source | histone cluster 1, H2bn | 19368 | -1.195 | -0.4162 | Yes |
| 43 | HIST1H2BD | HIST1H2BD Entrez, Source | histone cluster 1, H2bd | 19576 | -1.507 | -0.3681 | Yes |
| 44 | HIST1H4H | HIST1H4H Entrez, Source | histone cluster 1, H4h | 19623 | -1.605 | -0.3081 | Yes |
| 45 | HIST1H4I | HIST1H4I Entrez, Source | histone cluster 1, H4i | 19684 | -1.758 | -0.2428 | Yes |
| 46 | HIST1H2BK | HIST1H2BK Entrez, Source | histone cluster 1, H2bk | 19715 | -1.903 | -0.1704 | Yes |
| 47 | HIST1H2BG | HIST1H2BG Entrez, Source | histone cluster 1, H2bg | 19741 | -2.101 | -0.0901 | Yes |
| 48 | HIST1H2BC | HIST1H2BC Entrez, Source | histone cluster 1, H2bc | 19771 | -2.393 | 0.0014 | Yes |
