Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 0 |
| GeneSet | REACTOME_MEIOTIC_SYNAPSIS |
| Enrichment Score (ES) | -0.71635437 |
| Normalized Enrichment Score (NES) | -1.969123 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0039712167 |
| FWER p-Value | 0.031 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HIST2H2AC | HIST2H2AC Entrez, Source | histone cluster 2, H2ac | 861 | 0.511 | -0.0134 | No |
| 2 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 1113 | 0.447 | 0.0022 | No |
| 3 | SYNE1 | SYNE1 Entrez, Source | spectrin repeat containing, nuclear envelope 1 | 2285 | 0.249 | -0.0451 | No |
| 4 | ATR | ATR Entrez, Source | ataxia telangiectasia and Rad3 related | 4742 | 0.084 | -0.1730 | No |
| 5 | TINF2 | TINF2 Entrez, Source | TERF1 (TRF1)-interacting nuclear factor 2 | 4848 | 0.080 | -0.1734 | No |
| 6 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 5801 | 0.056 | -0.2215 | No |
| 7 | TERF2 | TERF2 Entrez, Source | telomeric repeat binding factor 2 | 6508 | 0.042 | -0.2571 | No |
| 8 | SMC1A | SMC1A Entrez, Source | structural maintenance of chromosomes 1A | 6987 | 0.033 | -0.2809 | No |
| 9 | SMC1B | SMC1B Entrez, Source | structural maintenance of chromosomes 1B | 7273 | 0.028 | -0.2946 | No |
| 10 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 8415 | 0.010 | -0.3559 | No |
| 11 | SYNE2 | SYNE2 Entrez, Source | spectrin repeat containing, nuclear envelope 2 | 8880 | 0.004 | -0.3808 | No |
| 12 | LMNA | LMNA Entrez, Source | lamin A/C | 8986 | 0.002 | -0.3864 | No |
| 13 | HSPA2 | HSPA2 Entrez, Source | heat shock 70kDa protein 2 | 9198 | -0.001 | -0.3978 | No |
| 14 | ACD | ACD Entrez, Source | adrenocortical dysplasia homolog (mouse) | 9473 | -0.005 | -0.4123 | No |
| 15 | REC8 | 9519 | -0.006 | -0.4144 | No | ||
| 16 | UBE2I | UBE2I Entrez, Source | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 9535 | -0.006 | -0.4148 | No |
| 17 | STAG3 | STAG3 Entrez, Source | stromal antigen 3 | 9620 | -0.007 | -0.4189 | No |
| 18 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 10073 | -0.014 | -0.4426 | No |
| 19 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 10371 | -0.018 | -0.4575 | No |
| 20 | STAG1 | STAG1 Entrez, Source | stromal antigen 1 | 10553 | -0.021 | -0.4660 | No |
| 21 | SUN2 | 10626 | -0.022 | -0.4684 | No | ||
| 22 | POT1 | POT1 Entrez, Source | POT1 protection of telomeres 1 homolog (S. pombe) | 10982 | -0.029 | -0.4858 | No |
| 23 | HIST1H4E | HIST1H4E Entrez, Source | histone cluster 1, H4e | 11068 | -0.031 | -0.4884 | No |
| 24 | SMC3 | SMC3 Entrez, Source | structural maintenance of chromosomes 3 | 11712 | -0.043 | -0.5205 | No |
| 25 | RAD21 | RAD21 Entrez, Source | RAD21 homolog (S. pombe) | 11731 | -0.043 | -0.5187 | No |
| 26 | DIDO1 | DIDO1 Entrez, Source | death inducer-obliterator 1 | 12686 | -0.066 | -0.5662 | No |
| 27 | HIST1H4H | HIST1H4H Entrez, Source | histone cluster 1, H4h | 12747 | -0.068 | -0.5650 | No |
| 28 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 13122 | -0.079 | -0.5801 | No |
| 29 | STAG2 | STAG2 Entrez, Source | stromal antigen 2 | 13485 | -0.092 | -0.5938 | No |
| 30 | HIST1H2BH | HIST1H2BH Entrez, Source | histone cluster 1, H2bh | 13513 | -0.093 | -0.5892 | No |
| 31 | TERF2IP | TERF2IP Entrez, Source | telomeric repeat binding factor 2, interacting protein | 14391 | -0.138 | -0.6278 | No |
| 32 | HIST1H2AE | HIST1H2AE Entrez, Source | histone cluster 1, H2ae | 15559 | -0.226 | -0.6764 | No |
| 33 | HIST1H2BE | HIST1H2BE Entrez, Source | histone cluster 1, H2be | 16046 | -0.283 | -0.6843 | Yes |
| 34 | HIST1H2BC | HIST1H2BC Entrez, Source | histone cluster 1, H2bc | 16155 | -0.298 | -0.6707 | Yes |
| 35 | HIST2H2BE | HIST2H2BE Entrez, Source | histone cluster 2, H2be | 16205 | -0.307 | -0.6533 | Yes |
| 36 | SYCP1 | SYCP1 Entrez, Source | synaptonemal complex protein 1 | 17367 | -0.539 | -0.6812 | Yes |
| 37 | HIST4H4 | HIST4H4 Entrez, Source | histone cluster 4, H4 | 17801 | -0.696 | -0.6592 | Yes |
| 38 | HIST1H2BK | HIST1H2BK Entrez, Source | histone cluster 1, H2bk | 17855 | -0.724 | -0.6148 | Yes |
| 39 | HIST1H2BG | HIST1H2BG Entrez, Source | histone cluster 1, H2bg | 17876 | -0.733 | -0.5680 | Yes |
| 40 | HIST1H2BD | HIST1H2BD Entrez, Source | histone cluster 1, H2bd | 18048 | -0.840 | -0.5225 | Yes |
| 41 | HIST1H2AC | HIST1H2AC Entrez, Source | histone cluster 1, H2ac | 18050 | -0.843 | -0.4674 | Yes |
| 42 | HIST1H2BO | HIST1H2BO Entrez, Source | histone cluster 1, H2bo | 18317 | -1.150 | -0.4067 | Yes |
| 43 | SYCP2 | SYCP2 Entrez, Source | synaptonemal complex protein 2 | 18321 | -1.158 | -0.3313 | Yes |
| 44 | HIST3H2BB | HIST3H2BB Entrez, Source | histone cluster 3, H2bb | 18365 | -1.265 | -0.2510 | Yes |
| 45 | HIST1H2BN | HIST1H2BN Entrez, Source | histone cluster 1, H2bn | 18373 | -1.283 | -0.1676 | Yes |
| 46 | HIST1H4I | HIST1H4I Entrez, Source | histone cluster 1, H4i | 18380 | -1.300 | -0.0830 | Yes |
| 47 | HIST1H2BJ | HIST1H2BJ Entrez, Source | histone cluster 1, H2bj | 18393 | -1.337 | 0.0037 | Yes |
