Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50832_collapsed_to_symbols.NS50832.cls #558AP2_versus_S78.NS50832.cls #558AP2_versus_S78_repos |
| Phenotype | NS50832.cls#558AP2_versus_S78_repos |
| Upregulated in class | 0 |
| GeneSet | GO_ANION_CHANNEL_ACTIVITY |
| Enrichment Score (ES) | -0.64311236 |
| Normalized Enrichment Score (NES) | -1.6524122 |
| Nominal p-value | 0.002624672 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GABRD | GABRD Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, delta | 133 | 3.320 | 0.0456 | No |
| 2 | GLRA4 | GLRA4 Entrez, Source | glycine receptor, alpha 4 | 875 | 1.324 | 0.0309 | No |
| 3 | FXYD3 | FXYD3 Entrez, Source | FXYD domain containing ion transport regulator 3 | 1115 | 1.106 | 0.0368 | No |
| 4 | SLC17A7 | SLC17A7 Entrez, Source | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 | 1428 | 0.890 | 0.0358 | No |
| 5 | CFTR | CFTR Entrez, Source | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 2143 | 0.607 | 0.0112 | No |
| 6 | CLCNKA | CLCNKA Entrez, Source | chloride channel Ka | 2212 | 0.591 | 0.0172 | No |
| 7 | GLRB | GLRB Entrez, Source | glycine receptor, beta | 2718 | 0.461 | 0.0003 | No |
| 8 | TTYH1 | TTYH1 Entrez, Source | tweety homolog 1 (Drosophila) | 3746 | 0.278 | -0.0445 | No |
| 9 | GABRQ | GABRQ Entrez, Source | gamma-aminobutyric acid (GABA) receptor, theta | 4502 | 0.205 | -0.0774 | No |
| 10 | GPR89A | GPR89A Entrez, Source | G protein-coupled receptor 89A | 4689 | 0.192 | -0.0832 | No |
| 11 | SLC26A5 | SLC26A5 Entrez, Source | solute carrier family 26, member 5 (prestin) | 4847 | 0.181 | -0.0879 | No |
| 12 | CLCN6 | CLCN6 Entrez, Source | chloride channel 6 | 5375 | 0.152 | -0.1107 | No |
| 13 | SLC26A2 | SLC26A2 Entrez, Source | solute carrier family 26 (sulfate transporter), member 2 | 5950 | 0.124 | -0.1362 | No |
| 14 | SLC26A6 | SLC26A6 Entrez, Source | solute carrier family 26, member 6 | 6015 | 0.121 | -0.1374 | No |
| 15 | VDAC3 | VDAC3 Entrez, Source | voltage-dependent anion channel 3 | 6037 | 0.120 | -0.1365 | No |
| 16 | ANO7 | 6107 | 0.118 | -0.1379 | No | ||
| 17 | GABRG3 | GABRG3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, gamma 3 | 6163 | 0.115 | -0.1388 | No |
| 18 | LRRC8A | LRRC8A Entrez, Source | leucine rich repeat containing 8 family, member A | 6342 | 0.108 | -0.1456 | No |
| 19 | ANO1 | 6775 | 0.094 | -0.1648 | No | ||
| 20 | VDAC1 | VDAC1 Entrez, Source | voltage-dependent anion channel 1 | 7474 | 0.073 | -0.1970 | No |
| 21 | CLIC1 | CLIC1 Entrez, Source | chloride intracellular channel 1 | 7736 | 0.066 | -0.2084 | No |
| 22 | SLC26A10 | SLC26A10 Entrez, Source | solute carrier family 26, member 10 | 9336 | 0.025 | -0.2845 | No |
| 23 | CLCN7 | CLCN7 Entrez, Source | chloride channel 7 | 10296 | 0.001 | -0.3303 | No |
| 24 | VDAC2 | VDAC2 Entrez, Source | voltage-dependent anion channel 2 | 10511 | -0.004 | -0.3404 | No |
| 25 | CLCN5 | CLCN5 Entrez, Source | chloride channel 5 (nephrolithiasis 2, X-linked, Dent disease) | 10602 | -0.007 | -0.3446 | No |
| 26 | CLCN4 | CLCN4 Entrez, Source | chloride channel 4 | 10863 | -0.013 | -0.3569 | No |
| 27 | TTYH3 | TTYH3 Entrez, Source | tweety homolog 3 (Drosophila) | 11310 | -0.025 | -0.3778 | No |
| 28 | CLCC1 | CLCC1 Entrez, Source | chloride channel CLIC-like 1 | 11323 | -0.026 | -0.3779 | No |
| 29 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 11579 | -0.034 | -0.3896 | No |
| 30 | ANO8 | 11837 | -0.042 | -0.4012 | No | ||
| 31 | ANO10 | 12540 | -0.065 | -0.4338 | No | ||
| 32 | LRRC8C | LRRC8C Entrez, Source | leucine rich repeat containing 8 family, member C | 12544 | -0.065 | -0.4329 | No |
| 33 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 13367 | -0.100 | -0.4706 | No |
| 34 | CLCN2 | CLCN2 Entrez, Source | chloride channel 2 | 13701 | -0.116 | -0.4847 | No |
| 35 | CLCN3 | CLCN3 Entrez, Source | chloride channel 3 | 13971 | -0.131 | -0.4955 | No |
| 36 | BEST2 | 14023 | -0.133 | -0.4959 | No | ||
| 37 | SLC26A11 | SLC26A11 Entrez, Source | solute carrier family 26, member 11 | 14057 | -0.136 | -0.4953 | No |
| 38 | ANO5 | 14492 | -0.166 | -0.5135 | No | ||
| 39 | GABRA3 | GABRA3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, alpha 3 | 14671 | -0.179 | -0.5192 | No |
| 40 | ANO6 | 15041 | -0.207 | -0.5336 | No | ||
| 41 | GABRP | GABRP Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, pi | 15262 | -0.226 | -0.5405 | No |
| 42 | LRRC8D | LRRC8D Entrez, Source | leucine rich repeat containing 8 family, member D | 15328 | -0.233 | -0.5400 | No |
| 43 | ANO9 | 15380 | -0.237 | -0.5387 | No | ||
| 44 | TTYH2 | TTYH2 Entrez, Source | tweety homolog 2 (Drosophila) | 15756 | -0.277 | -0.5523 | No |
| 45 | GABRA5 | GABRA5 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, alpha 5 | 16114 | -0.321 | -0.5644 | No |
| 46 | GABRE | GABRE Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, epsilon | 16374 | -0.358 | -0.5711 | No |
| 47 | CLIC2 | CLIC2 Entrez, Source | chloride intracellular channel 2 | 16982 | -0.457 | -0.5930 | No |
| 48 | GABRR1 | GABRR1 Entrez, Source | gamma-aminobutyric acid (GABA) receptor, rho 1 | 17321 | -0.537 | -0.6007 | No |
| 49 | SLC26A1 | SLC26A1 Entrez, Source | solute carrier family 26 (sulfate transporter), member 1 | 17401 | -0.554 | -0.5959 | No |
| 50 | BEST4 | 17551 | -0.596 | -0.5936 | No | ||
| 51 | CLCNKB | CLCNKB Entrez, Source | chloride channel Kb | 17640 | -0.618 | -0.5882 | No |
| 52 | ANO4 | 17886 | -0.689 | -0.5891 | No | ||
| 53 | ANO2 | 18299 | -0.827 | -0.5958 | No | ||
| 54 | LRRC8E | LRRC8E Entrez, Source | leucine rich repeat containing 8 family, member E | 19289 | -1.273 | -0.6232 | Yes |
| 55 | SLC26A8 | SLC26A8 Entrez, Source | solute carrier family 26, member 8 | 19355 | -1.313 | -0.6058 | Yes |
| 56 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 19611 | -1.500 | -0.5945 | Yes |
| 57 | SLC1A4 | SLC1A4 Entrez, Source | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 19791 | -1.655 | -0.5771 | Yes |
| 58 | GABRG2 | GABRG2 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 19888 | -1.739 | -0.5545 | Yes |
| 59 | CLIC6 | CLIC6 Entrez, Source | chloride intracellular channel 6 | 19964 | -1.826 | -0.5295 | Yes |
| 60 | BSND | BSND Entrez, Source | Bartter syndrome, infantile, with sensorineural deafness (Barttin) | 20024 | -1.906 | -0.5025 | Yes |
| 61 | CLIC5 | CLIC5 Entrez, Source | chloride intracellular channel 5 | 20263 | -2.235 | -0.4789 | Yes |
| 62 | GABRB1 | GABRB1 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 1 | 20398 | -2.457 | -0.4468 | Yes |
| 63 | CLCN1 | CLCN1 Entrez, Source | chloride channel 1, skeletal muscle (Thomsen disease, autosomal dominant) | 20519 | -2.716 | -0.4100 | Yes |
| 64 | GABRA1 | GABRA1 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 20590 | -2.905 | -0.3679 | Yes |
| 65 | GABRG1 | GABRG1 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, gamma 1 | 20662 | -3.113 | -0.3226 | Yes |
| 66 | GABRB2 | GABRB2 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 2 | 20759 | -3.525 | -0.2720 | Yes |
| 67 | FXYD1 | FXYD1 Entrez, Source | FXYD domain containing ion transport regulator 1 (phospholemman) | 20773 | -3.615 | -0.2161 | Yes |
| 68 | GABRA4 | GABRA4 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, alpha 4 | 20891 | -4.536 | -0.1507 | Yes |
| 69 | BEST1 | 20921 | -4.925 | -0.0750 | Yes | ||
| 70 | GABRA2 | GABRA2 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, alpha 2 | 20966 | -5.000 | 0.0012 | Yes |
