Details for gene set GO_CARDIAC_SEPTUM_DEVELOPMENT[GSEA]

Table: GSEA Results Summary

Dataset	NS50832_collapsed_to_symbols.NS50832.cls #558AP2_versus_S78.NS50832.cls #558AP2_versus_S78_repos
Phenotype	NS50832.cls#558AP2_versus_S78_repos
Upregulated in class	1
GeneSet	GO_CARDIAC_SEPTUM_DEVELOPMENT
Enrichment Score (ES)	0.6181427
Normalized Enrichment Score (NES)	1.8674704
Nominal p-value	0.0
FDR q-value	0.07632094
FWER p-Value	0.466

Fig 1: Enrichment plot: GO_CARDIAC_SEPTUM_DEVELOPMENT   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	HAND1	HAND1 Entrez,  Source	heart and neural crest derivatives expressed 1	63	4.144	0.0915	Yes
2	MSX2	MSX2 Entrez,  Source	msh homeobox homolog 2 (Drosophila)	79	3.875	0.1791	Yes
3	PITX2	PITX2 Entrez,  Source	paired-like homeodomain transcription factor 2	223	2.814	0.2364	Yes
4	GATA6	GATA6 Entrez,  Source	GATA binding protein 6	237	2.741	0.2982	Yes
5	FGF8	FGF8 Entrez,  Source	fibroblast growth factor 8 (androgen-induced)	277	2.560	0.3547	Yes
6	PRDM1	PRDM1 Entrez,  Source	PR domain containing 1, with ZNF domain	326	2.379	0.4067	Yes
7	GJA5	GJA5 Entrez,  Source	gap junction protein, alpha 5, 40kDa (connexin 40)	433	2.053	0.4484	Yes
8	GATA3	GATA3 Entrez,  Source	GATA binding protein 3	505	1.890	0.4881	Yes
9	ISL1	ISL1 Entrez,  Source	ISL1 transcription factor, LIM/homeodomain, (islet-1)	558	1.772	0.5260	Yes
10	TBX3	TBX3 Entrez,  Source	T-box 3 (ulnar mammary syndrome)	569	1.753	0.5655	Yes
11	BMP4	BMP4 Entrez,  Source	bone morphogenetic protein 4	620	1.680	0.6014	Yes
12	TBX1	TBX1 Entrez,  Source	T-box 1	892	1.305	0.6181	Yes
13	NKX2-5	NKX2-5 Entrez,  Source	NK2 transcription factor related, locus 5 (Drosophila)	1370	0.926	0.6165	No
14	FZD1	FZD1 Entrez,  Source	frizzled homolog 1 (Drosophila)	1923	0.678	0.6055	No
15	LRP2	LRP2 Entrez,  Source	low density lipoprotein-related protein 2	2840	0.429	0.5715	No
16	MDM2	MDM2 Entrez,  Source	Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)	3005	0.396	0.5727	No
17	NPHP3	NPHP3 Entrez,  Source	nephronophthisis 3 (adolescent)	3270	0.347	0.5680	No
18	SMAD6	SMAD6 Entrez,  Source	SMAD, mothers against DPP homolog 6 (Drosophila)	3284	0.345	0.5752	No
19	CITED2	CITED2 Entrez,  Source	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	3316	0.341	0.5815	No
20	FGFRL1	FGFRL1 Entrez,  Source	fibroblast growth factor receptor-like 1	3700	0.284	0.5697	No
21	DHRS3	DHRS3 Entrez,  Source	dehydrogenase/reductase (SDR family) member 3	3752	0.277	0.5735	No
22	HEG1	HEG1 Entrez,  Source	HEG homolog 1 (zebrafish)	4054	0.242	0.5647	No
23	ZFPM1	ZFPM1 Entrez,  Source	zinc finger protein, multitype 1	4136	0.235	0.5662	No
24	RBM15	RBM15 Entrez,  Source	RNA binding motif protein 15	4219	0.227	0.5674	No
25	FRS2	FRS2 Entrez,  Source	fibroblast growth factor receptor substrate 2	4456	0.208	0.5609	No
26	GATA4	GATA4 Entrez,  Source	GATA binding protein 4	4707	0.191	0.5533	No
27	NOTCH1	NOTCH1 Entrez,  Source	Notch homolog 1, translocation-associated (Drosophila)	5526	0.144	0.5174	No
28	NDST1	NDST1 Entrez,  Source	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	5841	0.129	0.5054	No
29	SMO	SMO Entrez,  Source	smoothened homolog (Drosophila)	5916	0.125	0.5047	No
30	NOTCH2	NOTCH2 Entrez,  Source	Notch homolog 2 (Drosophila)	6422	0.105	0.4829	No
31	SUFU	SUFU Entrez,  Source	suppressor of fused homolog (Drosophila)	6496	0.102	0.4818	No
32	SOX4	SOX4 Entrez,  Source	SRY (sex determining region Y)-box 4	6940	0.088	0.4626	No
33	PROX1	PROX1 Entrez,  Source	prospero-related homeobox 1	7029	0.085	0.4603	No
34	NPRL3			7496	0.072	0.4397	No
35	MYH10	MYH10 Entrez,  Source	myosin, heavy chain 10, non-muscle	7808	0.064	0.4263	No
36	PARVA	PARVA Entrez,  Source	parvin, alpha	8541	0.045	0.3923	No
37	LUZP1	LUZP1 Entrez,  Source	leucine zipper protein 1	8698	0.042	0.3858	No
38	CYR61	CYR61 Entrez,  Source	cysteine-rich, angiogenic inducer, 61	8787	0.039	0.3825	No
39	DCTN5	DCTN5 Entrez,  Source	dynactin 5 (p25)	8831	0.038	0.3813	No
40	SALL4	SALL4 Entrez,  Source	sal-like 4 (Drosophila)	8987	0.034	0.3746	No
41	FGFR2	FGFR2 Entrez,  Source	ffer syndrome, Jackson-Weiss syndrome)	9005	0.033	0.3746	No
42	SMAD4	SMAD4 Entrez,  Source	SMAD, mothers against DPP homolog 4 (Drosophila)	9149	0.030	0.3684	No
43	TAB1			9389	0.024	0.3575	No
44	VANGL2	VANGL2 Entrez,  Source	vang-like 2 (van gogh, Drosophila)	9402	0.023	0.3575	No
45	SMAD7	SMAD7 Entrez,  Source	SMAD, mothers against DPP homolog 7 (Drosophila)	9450	0.022	0.3558	No
46	SOX11	SOX11 Entrez,  Source	SRY (sex determining region Y)-box 11	9608	0.019	0.3487	No
47	PTK7	PTK7 Entrez,  Source	PTK7 protein tyrosine kinase 7	9831	0.013	0.3383	No
48	AP2B1	AP2B1 Entrez,  Source	adaptor-related protein complex 2, beta 1 subunit	9897	0.011	0.3355	No
49	PLXND1	PLXND1 Entrez,  Source	plexin D1	10793	-0.012	0.2930	No
50	SNX17	SNX17 Entrez,  Source	sorting nexin 17	11090	-0.020	0.2793	No
51	DNM2	DNM2 Entrez,  Source	dynamin 2	11432	-0.029	0.2636	No
52	ANK2	ANK2 Entrez,  Source	ankyrin 2, neuronal	11580	-0.034	0.2574	No
53	SAV1	SAV1 Entrez,  Source	salvador homolog 1 (Drosophila)	11928	-0.045	0.2418	No
54	MAML1	MAML1 Entrez,  Source	mastermind-like 1 (Drosophila)	12246	-0.055	0.2279	No
55	PCSK5	PCSK5 Entrez,  Source	proprotein convertase subtilisin/kexin type 5	12530	-0.065	0.2158	No
56	DVL3	DVL3 Entrez,  Source	dishevelled, dsh homolog 3 (Drosophila)	12687	-0.071	0.2100	No
57	SALL1	SALL1 Entrez,  Source	sal-like 1 (Drosophila)	13043	-0.086	0.1950	No
58	WNT11	WNT11 Entrez,  Source	wingless-type MMTV integration site family, member 11	13442	-0.104	0.1783	No
59	ID2	ID2 Entrez,  Source	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	14109	-0.139	0.1496	No
60	TRIP11	TRIP11 Entrez,  Source	thyroid hormone receptor interactor 11	14171	-0.143	0.1500	No
61	HEYL	HEYL Entrez,  Source	hairy/enhancer-of-split related with YRPW motif-like	14258	-0.148	0.1492	No
62	WNT5A	WNT5A Entrez,  Source	wingless-type MMTV integration site family, member 5A	14532	-0.168	0.1400	No
63	LMO4	LMO4 Entrez,  Source	LIM domain only 4	14794	-0.190	0.1319	No
64	EGLN1	EGLN1 Entrez,  Source	egl nine homolog 1 (C. elegans)	15114	-0.212	0.1215	No
65	ACVR1	ACVR1 Entrez,  Source	activin A receptor, type I	15133	-0.214	0.1255	No
66	HES1	HES1 Entrez,  Source	hairy and enhancer of split 1, (Drosophila)	15160	-0.217	0.1292	No
67	LTBP1	LTBP1 Entrez,  Source	latent transforming growth factor beta binding protein 1	15360	-0.236	0.1250	No
68	JAG1	JAG1 Entrez,  Source	jagged 1 (Alagille syndrome)	15590	-0.257	0.1199	No
69	RARB	RARB Entrez,  Source	retinoic acid receptor, beta	16104	-0.320	0.1027	No
70	RARA	RARA Entrez,  Source	retinoic acid receptor, alpha	16221	-0.336	0.1048	No
71	HEY2	HEY2 Entrez,  Source	hairy/enhancer-of-split related with YRPW motif 2	16302	-0.348	0.1089	No
72	CRELD1	CRELD1 Entrez,  Source	cysteine-rich with EGF-like domains 1	16420	-0.365	0.1116	No
73	FZD2	FZD2 Entrez,  Source	frizzled homolog 2 (Drosophila)	16897	-0.441	0.0989	No
74	ZFPM2	ZFPM2 Entrez,  Source	zinc finger protein, multitype 2	16914	-0.444	0.1083	No
75	DAND5	DAND5 Entrez,  Source	DAN domain family, member 5	18241	-0.803	0.0632	No
76	ADAMTS6	ADAMTS6 Entrez,  Source	ADAM metallopeptidase with thrombospondin type 1 motif, 6	18310	-0.831	0.0789	No
77	HEY1	HEY1 Entrez,  Source	hairy/enhancer-of-split related with YRPW motif 1	18518	-0.902	0.0895	No
78	STRA6	STRA6 Entrez,  Source	stimulated by retinoic acid gene 6 homolog (mouse)	19257	-1.257	0.0829	No

Fig 2: GO_CARDIAC_SEPTUM_DEVELOPMENT   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: GO_CARDIAC_SEPTUM_DEVELOPMENT: Random ES distribution   
Gene set null distribution of ES for GO_CARDIAC_SEPTUM_DEVELOPMENT