Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50832_collapsed_to_symbols.NS50832.cls #558AP2_versus_S78.NS50832.cls #558AP2_versus_S78_repos |
| Phenotype | NS50832.cls#558AP2_versus_S78_repos |
| Upregulated in class | 1 |
| GeneSet | GO_CARDIAC_SEPTUM_MORPHOGENESIS |
| Enrichment Score (ES) | 0.6910974 |
| Normalized Enrichment Score (NES) | 1.9187661 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03886655 |
| FWER p-Value | 0.197 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HAND1 | HAND1 Entrez, Source | heart and neural crest derivatives expressed 1 | 63 | 4.144 | 0.1279 | Yes |
| 2 | MSX2 | MSX2 Entrez, Source | msh homeobox homolog 2 (Drosophila) | 79 | 3.875 | 0.2495 | Yes |
| 3 | PITX2 | PITX2 Entrez, Source | paired-like homeodomain transcription factor 2 | 223 | 2.814 | 0.3315 | Yes |
| 4 | GATA6 | GATA6 Entrez, Source | GATA binding protein 6 | 237 | 2.741 | 0.4175 | Yes |
| 5 | FGF8 | FGF8 Entrez, Source | fibroblast growth factor 8 (androgen-induced) | 277 | 2.560 | 0.4964 | Yes |
| 6 | GJA5 | GJA5 Entrez, Source | gap junction protein, alpha 5, 40kDa (connexin 40) | 433 | 2.053 | 0.5539 | Yes |
| 7 | ISL1 | ISL1 Entrez, Source | ISL1 transcription factor, LIM/homeodomain, (islet-1) | 558 | 1.772 | 0.6039 | Yes |
| 8 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 569 | 1.753 | 0.6588 | Yes |
| 9 | TBX1 | TBX1 Entrez, Source | T-box 1 | 892 | 1.305 | 0.6846 | Yes |
| 10 | NKX2-5 | NKX2-5 Entrez, Source | NK2 transcription factor related, locus 5 (Drosophila) | 1370 | 0.926 | 0.6911 | Yes |
| 11 | FZD1 | FZD1 Entrez, Source | frizzled homolog 1 (Drosophila) | 1923 | 0.678 | 0.6862 | No |
| 12 | MDM2 | MDM2 Entrez, Source | Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) | 3005 | 0.396 | 0.6471 | No |
| 13 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 3316 | 0.341 | 0.6430 | No |
| 14 | FGFRL1 | FGFRL1 Entrez, Source | fibroblast growth factor receptor-like 1 | 3700 | 0.284 | 0.6337 | No |
| 15 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 3752 | 0.277 | 0.6400 | No |
| 16 | ZFPM1 | ZFPM1 Entrez, Source | zinc finger protein, multitype 1 | 4136 | 0.235 | 0.6291 | No |
| 17 | RBM15 | RBM15 Entrez, Source | RNA binding motif protein 15 | 4219 | 0.227 | 0.6324 | No |
| 18 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 4707 | 0.191 | 0.6152 | No |
| 19 | NOTCH1 | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 5526 | 0.144 | 0.5807 | No |
| 20 | SMO | SMO Entrez, Source | smoothened homolog (Drosophila) | 5916 | 0.125 | 0.5661 | No |
| 21 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 6422 | 0.105 | 0.5453 | No |
| 22 | SOX4 | SOX4 Entrez, Source | SRY (sex determining region Y)-box 4 | 6940 | 0.088 | 0.5234 | No |
| 23 | PROX1 | PROX1 Entrez, Source | prospero-related homeobox 1 | 7029 | 0.085 | 0.5219 | No |
| 24 | PARVA | PARVA Entrez, Source | parvin, alpha | 8541 | 0.045 | 0.4511 | No |
| 25 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 8787 | 0.039 | 0.4407 | No |
| 26 | FGFR2 | FGFR2 Entrez, Source | ffer syndrome, Jackson-Weiss syndrome) | 9005 | 0.033 | 0.4314 | No |
| 27 | VANGL2 | VANGL2 Entrez, Source | vang-like 2 (van gogh, Drosophila) | 9402 | 0.023 | 0.4132 | No |
| 28 | SMAD7 | SMAD7 Entrez, Source | SMAD, mothers against DPP homolog 7 (Drosophila) | 9450 | 0.022 | 0.4117 | No |
| 29 | SOX11 | SOX11 Entrez, Source | SRY (sex determining region Y)-box 11 | 9608 | 0.019 | 0.4048 | No |
| 30 | SAV1 | SAV1 Entrez, Source | salvador homolog 1 (Drosophila) | 11928 | -0.045 | 0.2955 | No |
| 31 | DVL3 | DVL3 Entrez, Source | dishevelled, dsh homolog 3 (Drosophila) | 12687 | -0.071 | 0.2615 | No |
| 32 | WNT11 | WNT11 Entrez, Source | wingless-type MMTV integration site family, member 11 | 13442 | -0.104 | 0.2288 | No |
| 33 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 14109 | -0.139 | 0.2014 | No |
| 34 | HEYL | HEYL Entrez, Source | hairy/enhancer-of-split related with YRPW motif-like | 14258 | -0.148 | 0.1990 | No |
| 35 | WNT5A | WNT5A Entrez, Source | wingless-type MMTV integration site family, member 5A | 14532 | -0.168 | 0.1913 | No |
| 36 | EGLN1 | EGLN1 Entrez, Source | egl nine homolog 1 (C. elegans) | 15114 | -0.212 | 0.1703 | No |
| 37 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 15133 | -0.214 | 0.1762 | No |
| 38 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 15160 | -0.217 | 0.1818 | No |
| 39 | JAG1 | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 15590 | -0.257 | 0.1694 | No |
| 40 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 16104 | -0.320 | 0.1550 | No |
| 41 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 16221 | -0.336 | 0.1601 | No |
| 42 | HEY2 | HEY2 Entrez, Source | hairy/enhancer-of-split related with YRPW motif 2 | 16302 | -0.348 | 0.1673 | No |
| 43 | FZD2 | FZD2 Entrez, Source | frizzled homolog 2 (Drosophila) | 16897 | -0.441 | 0.1528 | No |
| 44 | ZFPM2 | ZFPM2 Entrez, Source | zinc finger protein, multitype 2 | 16914 | -0.444 | 0.1661 | No |
| 45 | HEY1 | HEY1 Entrez, Source | hairy/enhancer-of-split related with YRPW motif 1 | 18518 | -0.902 | 0.1181 | No |
