Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50832_collapsed_to_symbols.NS50832.cls #558AP2_versus_S78.NS50832.cls #558AP2_versus_S78_repos |
| Phenotype | NS50832.cls#558AP2_versus_S78_repos |
| Upregulated in class | 1 |
| GeneSet | GO_LUNG_MORPHOGENESIS |
| Enrichment Score (ES) | 0.6932969 |
| Normalized Enrichment Score (NES) | 1.8708824 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.08085493 |
| FWER p-Value | 0.444 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HHIP | HHIP Entrez, Source | hedgehog interacting protein | 128 | 3.347 | 0.1657 | Yes |
| 2 | PITX2 | PITX2 Entrez, Source | paired-like homeodomain transcription factor 2 | 223 | 2.814 | 0.3057 | Yes |
| 3 | FGF8 | FGF8 Entrez, Source | fibroblast growth factor 8 (androgen-induced) | 277 | 2.560 | 0.4346 | Yes |
| 4 | WNT7B | WNT7B Entrez, Source | wingless-type MMTV integration site family, member 7B | 290 | 2.527 | 0.5637 | Yes |
| 5 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 620 | 1.680 | 0.6343 | Yes |
| 6 | HHEX | HHEX Entrez, Source | homeobox, hematopoietically expressed | 846 | 1.359 | 0.6933 | Yes |
| 7 | LIF | LIF Entrez, Source | leukemia inhibitory factor (cholinergic differentiation factor) | 1777 | 0.740 | 0.6869 | No |
| 8 | TNC | TNC Entrez, Source | tenascin C (hexabrachion) | 2350 | 0.549 | 0.6878 | No |
| 9 | RSPO2 | RSPO2 Entrez, Source | R-spondin 2 homolog (Xenopus laevis) | 3326 | 0.340 | 0.6587 | No |
| 10 | NODAL | NODAL Entrez, Source | nodal homolog (mouse) | 3518 | 0.308 | 0.6654 | No |
| 11 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 3829 | 0.267 | 0.6643 | No |
| 12 | SPRY1 | SPRY1 Entrez, Source | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 5336 | 0.153 | 0.6003 | No |
| 13 | CTSZ | CTSZ Entrez, Source | cathepsin Z | 5822 | 0.130 | 0.5838 | No |
| 14 | NOG | NOG Entrez, Source | noggin | 5925 | 0.125 | 0.5853 | No |
| 15 | CELSR1 | CELSR1 Entrez, Source | cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) | 6486 | 0.103 | 0.5639 | No |
| 16 | SEC24B | SEC24B Entrez, Source | SEC24 related gene family, member B (S. cerevisiae) | 6819 | 0.092 | 0.5528 | No |
| 17 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 7800 | 0.064 | 0.5093 | No |
| 18 | MAPK8IP3 | MAPK8IP3 Entrez, Source | mitogen-activated protein kinase 8 interacting protein 3 | 8357 | 0.050 | 0.4853 | No |
| 19 | FGFR2 | FGFR2 Entrez, Source | ffer syndrome, Jackson-Weiss syndrome) | 9005 | 0.033 | 0.4561 | No |
| 20 | CTSH | CTSH Entrez, Source | cathepsin H | 9135 | 0.030 | 0.4515 | No |
| 21 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 9179 | 0.029 | 0.4509 | No |
| 22 | VANGL2 | VANGL2 Entrez, Source | vang-like 2 (van gogh, Drosophila) | 9402 | 0.023 | 0.4415 | No |
| 23 | SOX11 | SOX11 Entrez, Source | SRY (sex determining region Y)-box 11 | 9608 | 0.019 | 0.4327 | No |
| 24 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 9928 | 0.011 | 0.4180 | No |
| 25 | DAG1 | DAG1 Entrez, Source | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 9942 | 0.010 | 0.4179 | No |
| 26 | YAP1 | YAP1 Entrez, Source | Yes-associated protein 1, 65kDa | 9964 | 0.010 | 0.4174 | No |
| 27 | MAP2K2 | MAP2K2 Entrez, Source | mitogen-activated protein kinase kinase 2 | 10506 | -0.004 | 0.3918 | No |
| 28 | STK40 | STK40 Entrez, Source | serine/threonine kinase 40 | 10703 | -0.010 | 0.3829 | No |
| 29 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 11216 | -0.023 | 0.3597 | No |
| 30 | DLG5 | DLG5 Entrez, Source | discs, large homolog 5 (Drosophila) | 11240 | -0.024 | 0.3598 | No |
| 31 | SRF | SRF Entrez, Source | serum response factor (c-fos serum response element-binding transcription factor) | 11583 | -0.034 | 0.3452 | No |
| 32 | PLOD3 | PLOD3 Entrez, Source | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 11694 | -0.038 | 0.3419 | No |
| 33 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 12419 | -0.061 | 0.3105 | No |
| 34 | KRAS | KRAS Entrez, Source | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 12724 | -0.073 | 0.2997 | No |
| 35 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 13780 | -0.120 | 0.2555 | No |
| 36 | GRHL2 | GRHL2 Entrez, Source | grainyhead-like 2 (Drosophila) | 13840 | -0.124 | 0.2591 | No |
| 37 | RDH10 | RDH10 Entrez, Source | retinol dehydrogenase 10 (all-trans) | 15101 | -0.211 | 0.2098 | No |
| 38 | TCF21 | TCF21 Entrez, Source | transcription factor 21 | 17731 | -0.642 | 0.1173 | No |
| 39 | SOX9 | SOX9 Entrez, Source | SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) | 18063 | -0.745 | 0.1397 | No |
