Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50832_collapsed_to_symbols.NS50832.cls #558AP2_versus_S78.NS50832.cls #558AP2_versus_S78_repos |
| Phenotype | NS50832.cls#558AP2_versus_S78_repos |
| Upregulated in class | 0 |
| GeneSet | GO_NEGATIVE_REGULATION_OF_TRANSLATIONAL_INITIATION |
| Enrichment Score (ES) | -0.76288843 |
| Normalized Enrichment Score (NES) | -1.6032776 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.8367786 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RBM4 | RBM4 Entrez, Source | RNA binding motif protein 4 | 4581 | 0.199 | -0.1875 | No |
| 2 | EIF2S1 | EIF2S1 Entrez, Source | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 4597 | 0.198 | -0.1575 | No |
| 3 | PAIP2B | 6667 | 0.097 | -0.2411 | No | ||
| 4 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 7778 | 0.064 | -0.2841 | No |
| 5 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 9044 | 0.032 | -0.3393 | No |
| 6 | EIF2AK3 | EIF2AK3 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 3 | 9087 | 0.031 | -0.3365 | No |
| 7 | PAIP2 | PAIP2 Entrez, Source | poly(A) binding protein interacting protein 2 | 9240 | 0.027 | -0.3395 | No |
| 8 | TPR | TPR Entrez, Source | translocated promoter region (to activated MET oncogene) | 9400 | 0.023 | -0.3435 | No |
| 9 | EIF3E | 9431 | 0.023 | -0.3414 | No | ||
| 10 | EIF4EBP2 | EIF4EBP2 Entrez, Source | eukaryotic translation initiation factor 4E binding protein 2 | 10360 | 0.000 | -0.3856 | No |
| 11 | EIF2AK1 | EIF2AK1 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 1 | 10513 | -0.004 | -0.3922 | No |
| 12 | EIF2B3 | EIF2B3 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa | 11121 | -0.020 | -0.4180 | No |
| 13 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 11331 | -0.026 | -0.4240 | No |
| 14 | EIF2B5 | EIF2B5 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa | 11368 | -0.027 | -0.4215 | No |
| 15 | EIF2B4 | EIF2B4 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 12024 | -0.048 | -0.4453 | No |
| 16 | EIF2AK4 | EIF2AK4 Entrez, Source | eukaryotic translation initiation factor 2 alpha kinase 4 | 12629 | -0.069 | -0.4635 | No |
| 17 | EIF4EBP1 | EIF4EBP1 Entrez, Source | eukaryotic translation initiation factor 4E binding protein 1 | 13962 | -0.131 | -0.5067 | No |
| 18 | EIF4EBP3 | EIF4EBP3 Entrez, Source | eukaryotic translation initiation factor 4E binding protein 3 | 14296 | -0.151 | -0.4992 | No |
| 19 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 16221 | -0.336 | -0.5388 | Yes |
| 20 | BANK1 | BANK1 Entrez, Source | B-cell scaffold protein with ankyrin repeats 1 | 20922 | -4.939 | 0.0033 | Yes |
