| Dataset | NS50832_collapsed_to_symbols.NS50832.cls #558AP2_versus_S78.NS50832.cls #558AP2_versus_S78_repos |
| Phenotype | NS50832.cls#558AP2_versus_S78_repos |
| Upregulated in class | 1 |
| GeneSet | KERLEY_RESPONSE_TO_CISPLATIN_UP |
| Enrichment Score (ES) | 0.70039034 |
| Normalized Enrichment Score (NES) | 1.8964174 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.052143686 |
| FWER p-Value | 0.294 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ACTA2 | ACTA2 Entrez,  Source | actin, alpha 2, smooth muscle, aorta | 139 | 3.252 | 0.1007 | Yes |
| 2 | FOSL1 | FOSL1 Entrez,  Source | FOS-like antigen 1 | 337 | 2.350 | 0.1688 | Yes |
| 3 | CXCL14 | CXCL14 Entrez,  Source | chemokine (C-X-C motif) ligand 14 | 338 | 2.348 | 0.2463 | Yes |
| 4 | CDKN1A | CDKN1A Entrez,  Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 383 | 2.199 | 0.3167 | Yes |
| 5 | BTG2 | BTG2 Entrez,  Source | BTG family, member 2 | 543 | 1.815 | 0.3690 | Yes |
| 6 | GDF15 | GDF15 Entrez,  Source | growth differentiation factor 15 | 707 | 1.545 | 0.4122 | Yes |
| 7 | TNFRSF10C | TNFRSF10C Entrez,  Source | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | 889 | 1.311 | 0.4468 | Yes |
| 8 | PHLDA3 | PHLDA3 Entrez,  Source | pleckstrin homology-like domain, family A, member 3 | 1202 | 1.034 | 0.4661 | Yes |
| 9 | INPP5D | INPP5D Entrez,  Source | inositol polyphosphate-5-phosphatase, 145kDa | 1351 | 0.936 | 0.4899 | Yes |
| 10 | PLK3 | PLK3 Entrez,  Source | polo-like kinase 3 (Drosophila) | 1569 | 0.825 | 0.5068 | Yes |
| 11 | TRIM22 | TRIM22 Entrez,  Source | tripartite motif-containing 22 | 1594 | 0.815 | 0.5325 | Yes |
| 12 | ZMAT3 | ZMAT3 Entrez,  Source | zinc finger, matrin type 3 | 1662 | 0.789 | 0.5553 | Yes |
| 13 | DRAM1 | 1765 | 0.743 | 0.5750 | Yes | ||
| 14 | PDE4A | PDE4A Entrez,  Source | phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) | 1803 | 0.732 | 0.5974 | Yes |
| 15 | SESN1 | SESN1 Entrez,  Source | sestrin 1 | 1816 | 0.723 | 0.6207 | Yes |
| 16 | FAS | FAS Entrez,  Source | Fas (TNF receptor superfamily, member 6) | 1961 | 0.665 | 0.6358 | Yes |
| 17 | FDXR | FDXR Entrez,  Source | ferredoxin reductase | 1974 | 0.659 | 0.6569 | Yes |
| 18 | RPS27L | RPS27L Entrez,  Source | ribosomal protein S27-like | 2219 | 0.587 | 0.6647 | Yes |
| 19 | DDB2 | DDB2 Entrez,  Source | damage-specific DNA binding protein 2, 48kDa | 2601 | 0.487 | 0.6626 | Yes |
| 20 | PLK2 | PLK2 Entrez,  Source | polo-like kinase 2 (Drosophila) | 2869 | 0.423 | 0.6638 | Yes |
| 21 | CAV1 | CAV1 Entrez,  Source | caveolin 1, caveolae protein, 22kDa | 2972 | 0.403 | 0.6722 | Yes |
| 22 | PROCR | PROCR Entrez,  Source | protein C receptor, endothelial (EPCR) | 3188 | 0.362 | 0.6739 | Yes |
| 23 | ANXA1 | ANXA1 Entrez,  Source | annexin A1 | 3295 | 0.344 | 0.6801 | Yes |
| 24 | STK17A | STK17A Entrez,  Source | serine/threonine kinase 17a (apoptosis-inducing) | 3565 | 0.300 | 0.6772 | Yes |
| 25 | PLAT | PLAT Entrez,  Source | plasminogen activator, tissue | 3710 | 0.283 | 0.6797 | Yes |
| 26 | LMNA | LMNA Entrez,  Source | lamin A/C | 3789 | 0.272 | 0.6849 | Yes |
| 27 | EPS8L2 | EPS8L2 Entrez,  Source | EPS8-like 2 | 3798 | 0.271 | 0.6935 | Yes |
| 28 | PPM1D | PPM1D Entrez,  Source | protein phosphatase 1D magnesium-dependent, delta isoform | 3838 | 0.266 | 0.7004 | Yes |
| 29 | DGKA | DGKA Entrez,  Source | diacylglycerol kinase, alpha 80kDa | 4544 | 0.201 | 0.6734 | No |
| 30 | FADS3 | FADS3 Entrez,  Source | fatty acid desaturase 3 | 5681 | 0.136 | 0.6236 | No |
| 31 | ISYNA1 | ISYNA1 Entrez,  Source | - | 5808 | 0.130 | 0.6219 | No |
| 32 | TP53TG1 | 6757 | 0.094 | 0.5798 | No | ||
| 33 | GLS2 | GLS2 Entrez,  Source | glutaminase 2 (liver, mitochondrial) | 8779 | 0.039 | 0.4846 | No |
| 34 | ALDH1A3 | ALDH1A3 Entrez,  Source | aldehyde dehydrogenase 1 family, member A3 | 10051 | 0.007 | 0.4242 | No |
| 35 | GADD45A | GADD45A Entrez,  Source | growth arrest and DNA-damage-inducible, alpha | 10345 | 0.000 | 0.4102 | No |
| 36 | ANXA4 | ANXA4 Entrez,  Source | annexin A4 | 11316 | -0.025 | 0.3648 | No |
| 37 | ANK1 | ANK1 Entrez,  Source | ankyrin 1, erythrocytic | 14475 | -0.165 | 0.2195 | No |
| 38 | NEFL | NEFL Entrez,  Source | neurofilament, light polypeptide 68kDa | 17093 | -0.482 | 0.1104 | No |
| 39 | SERPINE1 | SERPINE1 Entrez,  Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 17316 | -0.536 | 0.1175 | No |
| 40 | IER3 | IER3 Entrez,  Source | immediate early response 3 | 17993 | -0.721 | 0.1091 | No |
| 41 | DDIT4 | DDIT4 Entrez,  Source | DNA-damage-inducible transcript 4 | 18822 | -1.030 | 0.1035 | No |

