DatasetNS50832_collapsed_to_symbols.NS50832.cls
#558AP2_versus_S78.NS50832.cls
#558AP2_versus_S78_repos
PhenotypeNS50832.cls#558AP2_versus_S78_repos
Upregulated in class1
GeneSetKERLEY_RESPONSE_TO_CISPLATIN_UP
Enrichment Score (ES)0.70039034
Normalized Enrichment Score (NES)1.8964174
Nominal p-value0.0
FDR q-value0.052143686
FWER p-Value0.294
Table: GSEA Results Summary



Fig 1: Enrichment plot: KERLEY_RESPONSE_TO_CISPLATIN_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ACTA2ACTA2
Entrez,  Source
actin, alpha 2, smooth muscle, aorta1393.2520.1007Yes
2FOSL1FOSL1
Entrez,  Source
FOS-like antigen 13372.3500.1688Yes
3CXCL14CXCL14
Entrez,  Source
chemokine (C-X-C motif) ligand 143382.3480.2463Yes
4CDKN1ACDKN1A
Entrez,  Source
cyclin-dependent kinase inhibitor 1A (p21, Cip1)3832.1990.3167Yes
5BTG2BTG2
Entrez,  Source
BTG family, member 25431.8150.3690Yes
6GDF15GDF15
Entrez,  Source
growth differentiation factor 157071.5450.4122Yes
7TNFRSF10CTNFRSF10C
Entrez,  Source
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain8891.3110.4468Yes
8PHLDA3PHLDA3
Entrez,  Source
pleckstrin homology-like domain, family A, member 312021.0340.4661Yes
9INPP5DINPP5D
Entrez,  Source
inositol polyphosphate-5-phosphatase, 145kDa13510.9360.4899Yes
10PLK3PLK3
Entrez,  Source
polo-like kinase 3 (Drosophila)15690.8250.5068Yes
11TRIM22TRIM22
Entrez,  Source
tripartite motif-containing 2215940.8150.5325Yes
12ZMAT3ZMAT3
Entrez,  Source
zinc finger, matrin type 316620.7890.5553Yes
13DRAM117650.7430.5750Yes
14PDE4APDE4A
Entrez,  Source
phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)18030.7320.5974Yes
15SESN1SESN1
Entrez,  Source
sestrin 118160.7230.6207Yes
16FASFAS
Entrez,  Source
Fas (TNF receptor superfamily, member 6)19610.6650.6358Yes
17FDXRFDXR
Entrez,  Source
ferredoxin reductase19740.6590.6569Yes
18RPS27LRPS27L
Entrez,  Source
ribosomal protein S27-like22190.5870.6647Yes
19DDB2DDB2
Entrez,  Source
damage-specific DNA binding protein 2, 48kDa26010.4870.6626Yes
20PLK2PLK2
Entrez,  Source
polo-like kinase 2 (Drosophila)28690.4230.6638Yes
21CAV1CAV1
Entrez,  Source
caveolin 1, caveolae protein, 22kDa29720.4030.6722Yes
22PROCRPROCR
Entrez,  Source
protein C receptor, endothelial (EPCR)31880.3620.6739Yes
23ANXA1ANXA1
Entrez,  Source
annexin A132950.3440.6801Yes
24STK17ASTK17A
Entrez,  Source
serine/threonine kinase 17a (apoptosis-inducing)35650.3000.6772Yes
25PLATPLAT
Entrez,  Source
plasminogen activator, tissue37100.2830.6797Yes
26LMNALMNA
Entrez,  Source
lamin A/C37890.2720.6849Yes
27EPS8L2EPS8L2
Entrez,  Source
EPS8-like 237980.2710.6935Yes
28PPM1DPPM1D
Entrez,  Source
protein phosphatase 1D magnesium-dependent, delta isoform38380.2660.7004Yes
29DGKADGKA
Entrez,  Source
diacylglycerol kinase, alpha 80kDa45440.2010.6734No
30FADS3FADS3
Entrez,  Source
fatty acid desaturase 356810.1360.6236No
31ISYNA1ISYNA1
Entrez,  Source
-58080.1300.6219No
32TP53TG167570.0940.5798No
33GLS2GLS2
Entrez,  Source
glutaminase 2 (liver, mitochondrial)87790.0390.4846No
34ALDH1A3ALDH1A3
Entrez,  Source
aldehyde dehydrogenase 1 family, member A3100510.0070.4242No
35GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha103450.0000.4102No
36ANXA4ANXA4
Entrez,  Source
annexin A411316-0.0250.3648No
37ANK1ANK1
Entrez,  Source
ankyrin 1, erythrocytic14475-0.1650.2195No
38NEFLNEFL
Entrez,  Source
neurofilament, light polypeptide 68kDa17093-0.4820.1104No
39SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 117316-0.5360.1175No
40IER3IER3
Entrez,  Source
immediate early response 317993-0.7210.1091No
41DDIT4DDIT4
Entrez,  Source
DNA-damage-inducible transcript 418822-1.0300.1035No
Table: GSEA details [plain text format]



Fig 2: KERLEY_RESPONSE_TO_CISPLATIN_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: KERLEY_RESPONSE_TO_CISPLATIN_UP: Random ES distribution   
Gene set null distribution of ES for KERLEY_RESPONSE_TO_CISPLATIN_UP