Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50832_collapsed_to_symbols.NS50832.cls #558AP2_versus_S78.NS50832.cls #558AP2_versus_S78_repos |
| Phenotype | NS50832.cls#558AP2_versus_S78_repos |
| Upregulated in class | 0 |
| GeneSet | REACTOME_RNA_POL_I_PROMOTER_OPENING |
| Enrichment Score (ES) | -0.677941 |
| Normalized Enrichment Score (NES) | -1.6038055 |
| Nominal p-value | 0.011173184 |
| FDR q-value | 0.88917077 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 1112 | 1.110 | -0.0270 | No |
| 2 | HIST1H4D | HIST1H4D Entrez, Source | histone cluster 1, H4d | 1674 | 0.784 | -0.0354 | No |
| 3 | HIST1H4H | HIST1H4H Entrez, Source | histone cluster 1, H4h | 1800 | 0.733 | -0.0242 | No |
| 4 | HIST1H2BC | HIST1H2BC Entrez, Source | histone cluster 1, H2bc | 1804 | 0.731 | -0.0071 | No |
| 5 | HIST2H2AC | HIST2H2AC Entrez, Source | histone cluster 2, H2ac | 1857 | 0.707 | 0.0070 | No |
| 6 | HIST1H2AE | HIST1H2AE Entrez, Source | histone cluster 1, H2ae | 2062 | 0.630 | 0.0120 | No |
| 7 | HIST1H3J | HIST1H3J Entrez, Source | histone cluster 1, H3j | 3655 | 0.289 | -0.0571 | No |
| 8 | HIST1H3F | HIST1H3F Entrez, Source | histone cluster 1, H3f | 4421 | 0.211 | -0.0887 | No |
| 9 | H3F3A | H3F3A Entrez, Source | H3 histone, family 3A | 6169 | 0.115 | -0.1694 | No |
| 10 | UBTF | UBTF Entrez, Source | upstream binding transcription factor, RNA polymerase I | 6288 | 0.111 | -0.1724 | No |
| 11 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 6444 | 0.104 | -0.1774 | No |
| 12 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 7072 | 0.084 | -0.2053 | No |
| 13 | H3F3B | H3F3B Entrez, Source | H3 histone, family 3B (H3.3B) | 9123 | 0.030 | -0.3024 | No |
| 14 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 11216 | -0.023 | -0.4017 | No |
| 15 | MBD2 | MBD2 Entrez, Source | methyl-CpG binding domain protein 2 | 11517 | -0.031 | -0.4153 | No |
| 16 | HIST1H2BH | HIST1H2BH Entrez, Source | histone cluster 1, H2bh | 13000 | -0.085 | -0.4840 | No |
| 17 | HIST1H2BK | HIST1H2BK Entrez, Source | histone cluster 1, H2bk | 13205 | -0.093 | -0.4916 | No |
| 18 | HIST1H2BE | HIST1H2BE Entrez, Source | histone cluster 1, H2be | 14463 | -0.164 | -0.5477 | No |
| 19 | HIST1H3I | HIST1H3I Entrez, Source | histone cluster 1, H3i | 16000 | -0.305 | -0.6139 | No |
| 20 | HIST1H3A | HIST1H3A Entrez, Source | histone cluster 1, H3a | 16043 | -0.311 | -0.6086 | No |
| 21 | HIST2H2BE | HIST2H2BE Entrez, Source | histone cluster 2, H2be | 16298 | -0.347 | -0.6125 | No |
| 22 | HIST1H2BG | HIST1H2BG Entrez, Source | histone cluster 1, H2bg | 16429 | -0.367 | -0.6101 | No |
| 23 | HIST1H2BF | HIST1H2BF Entrez, Source | histone cluster 1, H2bf | 17290 | -0.531 | -0.6387 | No |
| 24 | HIST1H3B | HIST1H3B Entrez, Source | histone cluster 1, H3b | 17776 | -0.654 | -0.6465 | No |
| 25 | HIST1H4E | HIST1H4E Entrez, Source | histone cluster 1, H4e | 17843 | -0.676 | -0.6338 | No |
| 26 | HIST1H2BD | HIST1H2BD Entrez, Source | histone cluster 1, H2bd | 18676 | -0.971 | -0.6507 | Yes |
| 27 | HIST1H3H | HIST1H3H Entrez, Source | histone cluster 1, H3h | 19248 | -1.251 | -0.6486 | Yes |
| 28 | HIST1H2AC | HIST1H2AC Entrez, Source | histone cluster 1, H2ac | 19503 | -1.417 | -0.6274 | Yes |
| 29 | HIST1H4I | HIST1H4I Entrez, Source | histone cluster 1, H4i | 19573 | -1.473 | -0.5961 | Yes |
| 30 | HIST1H3E | HIST1H3E Entrez, Source | histone cluster 1, H3e | 20289 | -2.284 | -0.5767 | Yes |
| 31 | HIST2H4A | HIST2H4A Entrez, Source | histone cluster 2, H4a | 20322 | -2.327 | -0.5235 | Yes |
| 32 | HIST4H4 | HIST4H4 Entrez, Source | histone cluster 4, H4 | 20390 | -2.440 | -0.4695 | Yes |
| 33 | HIST1H3G | HIST1H3G Entrez, Source | histone cluster 1, H3g | 20514 | -2.709 | -0.4117 | Yes |
| 34 | HIST1H3D | HIST1H3D Entrez, Source | histone cluster 1, H3d | 20594 | -2.926 | -0.3468 | Yes |
| 35 | HIST1H2BJ | HIST1H2BJ Entrez, Source | histone cluster 1, H2bj | 20719 | -3.326 | -0.2747 | Yes |
| 36 | HIST1H2BO | HIST1H2BO Entrez, Source | histone cluster 1, H2bo | 20735 | -3.400 | -0.1956 | Yes |
| 37 | HIST1H2BN | HIST1H2BN Entrez, Source | histone cluster 1, H2bn | 20809 | -3.847 | -0.1087 | Yes |
| 38 | HIST3H2BB | HIST3H2BB Entrez, Source | histone cluster 3, H2bb | 20947 | -5.000 | 0.0021 | Yes |
