Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50832_collapsed_to_symbols.NS50832.cls #558AP2_versus_S78.NS50832.cls #558AP2_versus_S78_repos |
| Phenotype | NS50832.cls#558AP2_versus_S78_repos |
| Upregulated in class | 1 |
| GeneSet | WARTERS_IR_RESPONSE_5GY |
| Enrichment Score (ES) | 0.7038027 |
| Normalized Enrichment Score (NES) | 1.8700255 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.076571025 |
| FWER p-Value | 0.445 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 383 | 2.199 | 0.0725 | Yes |
| 2 | RRAD | RRAD Entrez, Source | Ras-related associated with diabetes | 461 | 1.991 | 0.1510 | Yes |
| 3 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 543 | 1.815 | 0.2221 | Yes |
| 4 | GDNF | GDNF Entrez, Source | glial cell derived neurotrophic factor | 699 | 1.554 | 0.2789 | Yes |
| 5 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 707 | 1.545 | 0.3423 | Yes |
| 6 | POLH | POLH Entrez, Source | polymerase (DNA directed), eta | 775 | 1.461 | 0.3995 | Yes |
| 7 | WDR63 | WDR63 Entrez, Source | WD repeat domain 63 | 792 | 1.441 | 0.4582 | Yes |
| 8 | TNFRSF10C | TNFRSF10C Entrez, Source | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | 889 | 1.311 | 0.5078 | Yes |
| 9 | CHADL | 1258 | 1.000 | 0.5315 | Yes | ||
| 10 | VWCE | VWCE Entrez, Source | von Willebrand factor C and EGF domains | 1377 | 0.921 | 0.5639 | Yes |
| 11 | PLK3 | PLK3 Entrez, Source | polo-like kinase 3 (Drosophila) | 1569 | 0.825 | 0.5888 | Yes |
| 12 | SESN1 | SESN1 Entrez, Source | sestrin 1 | 1816 | 0.723 | 0.6070 | Yes |
| 13 | TP53INP1 | TP53INP1 Entrez, Source | tumor protein p53 inducible nuclear protein 1 | 1829 | 0.717 | 0.6360 | Yes |
| 14 | FAS | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 1961 | 0.665 | 0.6572 | Yes |
| 15 | FDXR | FDXR Entrez, Source | ferredoxin reductase | 1974 | 0.659 | 0.6838 | Yes |
| 16 | DDB2 | DDB2 Entrez, Source | damage-specific DNA binding protein 2, 48kDa | 2601 | 0.487 | 0.6741 | Yes |
| 17 | BBC3 | BBC3 Entrez, Source | BCL2 binding component 3 | 2645 | 0.478 | 0.6918 | Yes |
| 18 | MDM2 | MDM2 Entrez, Source | Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) | 3005 | 0.396 | 0.6910 | Yes |
| 19 | PLCL2 | PLCL2 Entrez, Source | phospholipase C-like 2 | 3642 | 0.291 | 0.6726 | Yes |
| 20 | PPM1D | PPM1D Entrez, Source | protein phosphatase 1D magnesium-dependent, delta isoform | 3838 | 0.266 | 0.6743 | Yes |
| 21 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 3926 | 0.254 | 0.6807 | Yes |
| 22 | NINJ1 | NINJ1 Entrez, Source | ninjurin 1 | 4000 | 0.247 | 0.6874 | Yes |
| 23 | HAS3 | HAS3 Entrez, Source | hyaluronan synthase 3 | 4084 | 0.240 | 0.6933 | Yes |
| 24 | E2F7 | E2F7 Entrez, Source | E2F transcription factor 7 | 4089 | 0.239 | 0.7030 | Yes |
| 25 | HSPA4L | HSPA4L Entrez, Source | heat shock 70kDa protein 4-like | 4267 | 0.224 | 0.7038 | Yes |
| 26 | NOTCH1 | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 5526 | 0.144 | 0.6497 | No |
| 27 | FAM84B | FAM84B Entrez, Source | family with sequence similarity 84, member B | 6032 | 0.121 | 0.6306 | No |
| 28 | FBXW7 | FBXW7 Entrez, Source | F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila) | 7720 | 0.066 | 0.5528 | No |
| 29 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 8755 | 0.040 | 0.5051 | No |
| 30 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 10345 | 0.000 | 0.4293 | No |
| 31 | BLOC1S2 | BLOC1S2 Entrez, Source | biogenesis of lysosome-related organelles complex-1, subunit 2 | 10555 | -0.006 | 0.4196 | No |
| 32 | PHLDB3 | PHLDB3 Entrez, Source | pleckstrin homology-like domain, family B, member 3 | 11515 | -0.031 | 0.3751 | No |
| 33 | COQ9 | COQ9 Entrez, Source | coenzyme Q9 homolog (S. cerevisiae) | 12384 | -0.059 | 0.3361 | No |
| 34 | THSD1 | THSD1 Entrez, Source | thrombospondin, type I, domain containing 1 | 15218 | -0.223 | 0.2101 | No |
| 35 | SH2D2A | SH2D2A Entrez, Source | SH2 domain protein 2A | 16507 | -0.380 | 0.1643 | No |
| 36 | ZNF597 | ZNF597 Entrez, Source | zinc finger protein 597 | 16722 | -0.410 | 0.1711 | No |
| 37 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 18212 | -0.790 | 0.1326 | No |
