DatasetNS50832_collapsed_to_symbols.NS50832.cls
#558AP2_versus_S78.NS50832.cls
#558AP2_versus_S78_repos
PhenotypeNS50832.cls#558AP2_versus_S78_repos
Upregulated in class1
GeneSetWARTERS_RESPONSE_TO_IR_SKIN
Enrichment Score (ES)0.69644755
Normalized Enrichment Score (NES)2.097812
Nominal p-value0.0
FDR q-value0.0019980841
FWER p-Value0.001
Table: GSEA Results Summary



Fig 1: Enrichment plot: WARTERS_RESPONSE_TO_IR_SKIN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PAPPAPAPPA
Entrez,  Source
pregnancy-associated plasma protein A, pappalysin 12422.7150.0651Yes
2SERPINB5SERPINB5
Entrez,  Source
serpin peptidase inhibitor, clade B (ovalbumin), member 53542.3020.1248Yes
3ETV7ETV7
Entrez,  Source
ets variant gene 7 (TEL2 oncogene)3742.2230.1866Yes
4CDKN1ACDKN1A
Entrez,  Source
cyclin-dependent kinase inhibitor 1A (p21, Cip1)3832.1990.2483Yes
5BTG2BTG2
Entrez,  Source
BTG family, member 25431.8150.2919Yes
6GDF15GDF15
Entrez,  Source
growth differentiation factor 157071.5450.3277Yes
7COMPCOMP
Entrez,  Source
cartilage oligomeric matrix protein7731.4630.3659Yes
8POLHPOLH
Entrez,  Source
polymerase (DNA directed), eta7751.4610.4071Yes
9WDR63WDR63
Entrez,  Source
WD repeat domain 637921.4410.4471Yes
10TNFRSF10CTNFRSF10C
Entrez,  Source
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain8891.3110.4795Yes
11CHADL12581.0000.4901Yes
12VWCEVWCE
Entrez,  Source
von Willebrand factor C and EGF domains13770.9210.5105Yes
13TRIM22TRIM22
Entrez,  Source
tripartite motif-containing 2215940.8150.5232Yes
14ZMAT3ZMAT3
Entrez,  Source
zinc finger, matrin type 316620.7890.5422Yes
15DRAM117650.7430.5583Yes
16SESN1SESN1
Entrez,  Source
sestrin 118160.7230.5764Yes
17TP53INP1TP53INP1
Entrez,  Source
tumor protein p53 inducible nuclear protein 118290.7170.5960Yes
18FASFAS
Entrez,  Source
Fas (TNF receptor superfamily, member 6)19610.6650.6086Yes
19FDXRFDXR
Entrez,  Source
ferredoxin reductase19740.6590.6266Yes
20RPS27LRPS27L
Entrez,  Source
ribosomal protein S27-like22190.5870.6315Yes
21DDB2DDB2
Entrez,  Source
damage-specific DNA binding protein 2, 48kDa26010.4870.6271Yes
22BBC3BBC3
Entrez,  Source
BCL2 binding component 326450.4780.6385Yes
23RAD51CRAD51C
Entrez,  Source
RAD51 homolog C (S. cerevisiae)27190.4600.6480Yes
24MDM2MDM2
Entrez,  Source
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)30050.3960.6456Yes
25CABYRCABYR
Entrez,  Source
calcium binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)33440.3360.6389Yes
26TRIAP1TRIAP1
Entrez,  Source
TP53 regulated inhibitor of apoptosis 134160.3250.6447Yes
27TGFBITGFBI
Entrez,  Source
transforming growth factor, beta-induced, 68kDa35010.3100.6494Yes
28NODALNODAL
Entrez,  Source
nodal homolog (mouse)35180.3080.6573Yes
29PLCL2PLCL2
Entrez,  Source
phospholipase C-like 236420.2910.6597Yes
30FGFBP336900.2860.6655Yes
31RRM2BRRM2B
Entrez,  Source
ribonucleotide reductase M2 B (TP53 inducible)36930.2850.6734Yes
32PPM1DPPM1D
Entrez,  Source
protein phosphatase 1D magnesium-dependent, delta isoform38380.2660.6740Yes
33GM2AGM2A
Entrez,  Source
GM2 ganglioside activator38890.2590.6790Yes
34NEAT139740.2500.6820Yes
35NINJ1NINJ1
Entrez,  Source
ninjurin 140000.2470.6878Yes
36E2F7E2F7
Entrez,  Source
E2F transcription factor 740890.2390.6903Yes
37MICALL242240.2270.6903Yes
38HSPA4LHSPA4L
Entrez,  Source
heat shock 70kDa protein 4-like42670.2240.6946Yes
39DEPDC7DEPDC7
Entrez,  Source
DEP domain containing 743580.2160.6964Yes
40NOTCH1NOTCH1
Entrez,  Source
Notch homolog 1, translocation-associated (Drosophila)55260.1440.6447No
41FBXO22FBXO22
Entrez,  Source
F-box protein 2255360.1430.6483No
42CCNG1CCNG1
Entrez,  Source
cyclin G159140.1250.6338No
43ZNF79ZNF79
Entrez,  Source
zinc finger protein 7966550.0970.6012No
44ANKRD33B67150.0950.6011No
45TP53TG167570.0940.6018No
46JAM3JAM3
Entrez,  Source
junctional adhesion molecule 372350.0800.5813No
47FBXW7FBXW7
Entrez,  Source
F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)77200.0660.5600No
48BTG3BTG3
Entrez,  Source
BTG family, member 378880.0620.5538No
49FRMD4AFRMD4A
Entrez,  Source
FERM domain containing 4A79290.0610.5536No
50ZNF219ZNF219
Entrez,  Source
zinc finger protein 21980240.0580.5507No
51MAGT183180.0500.5381No
52ID3ID3
Entrez,  Source
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein86460.0430.5237No
53RTTNRTTN
Entrez,  Source
rotatin96630.0170.4756No
54TMTC3TMTC3
Entrez,  Source
transmembrane and tetratricopeptide repeat containing 3100580.0070.4570No
55BLOC1S2BLOC1S2
Entrez,  Source
biogenesis of lysosome-related organelles complex-1, subunit 210555-0.0060.4335No
56PRF1PRF1
Entrez,  Source
perforin 1 (pore forming protein)11091-0.0200.4084No
57ANKRA2ANKRA2
Entrez,  Source
ankyrin repeat, family A (RFXANK-like), 211764-0.0400.3774No
58CES2CES2
Entrez,  Source
carboxylesterase 2 (intestine, liver)12008-0.0470.3672No
59ALCAMALCAM
Entrez,  Source
activated leukocyte cell adhesion molecule12403-0.0600.3501No
60PALM2-AKAP2PALM2-AKAP2
Entrez,  Source
-12683-0.0710.3387No
61PPFIBP1PPFIBP1
Entrez,  Source
PTPRF interacting protein, binding protein 1 (liprin beta 1)12781-0.0750.3362No
62DNAJB4DNAJB4
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 413234-0.0940.3173No
63THSD1THSD1
Entrez,  Source
thrombospondin, type I, domain containing 115218-0.2230.2288No
64SCN9ASCN9A
Entrez,  Source
sodium channel, voltage-gated, type IX, alpha15333-0.2340.2299No
65ASGR1ASGR1
Entrez,  Source
asialoglycoprotein receptor 116387-0.3600.1898No
66SNHG8SNHG8
Entrez,  Source
small nucleolar RNA host gene (non-protein coding) 817221-0.5150.1645No
67ICAM5ICAM5
Entrez,  Source
intercellular adhesion molecule 5, telencephalin17395-0.5530.1719No
Table: GSEA details [plain text format]



Fig 2: WARTERS_RESPONSE_TO_IR_SKIN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: WARTERS_RESPONSE_TO_IR_SKIN: Random ES distribution   
Gene set null distribution of ES for WARTERS_RESPONSE_TO_IR_SKIN