Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50832_collapsed_to_symbols.NS50832.cls #558AP2_versus_S78.NS50832.cls #558AP2_versus_S78_repos |
| Phenotype | NS50832.cls#558AP2_versus_S78_repos |
| Upregulated in class | 0 |
| GeneSet | ZHAN_MULTIPLE_MYELOMA_CD1_UP |
| Enrichment Score (ES) | -0.6827041 |
| Normalized Enrichment Score (NES) | -1.6161497 |
| Nominal p-value | 0.0043668123 |
| FDR q-value | 0.8285475 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RBP1 | RBP1 Entrez, Source | retinol binding protein 1, cellular | 2549 | 0.500 | -0.1061 | No |
| 2 | MTG1 | MTG1 Entrez, Source | mitochondrial GTPase 1 homolog (S. cerevisiae) | 4221 | 0.227 | -0.1788 | No |
| 3 | SYTL1 | SYTL1 Entrez, Source | synaptotagmin-like 1 | 5862 | 0.128 | -0.2531 | No |
| 4 | GPR63 | GPR63 Entrez, Source | G protein-coupled receptor 63 | 6174 | 0.115 | -0.2643 | No |
| 5 | ADRB1 | ADRB1 Entrez, Source | adrenergic, beta-1-, receptor | 6269 | 0.111 | -0.2654 | No |
| 6 | TOX2 | 7314 | 0.078 | -0.3128 | No | ||
| 7 | TBC1D16 | TBC1D16 Entrez, Source | TBC1 domain family, member 16 | 8237 | 0.052 | -0.3551 | No |
| 8 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 11615 | -0.035 | -0.5152 | No |
| 9 | PPP2R5E | PPP2R5E Entrez, Source | protein phosphatase 2, regulatory subunit B (B56), epsilon isoform | 12093 | -0.050 | -0.5365 | No |
| 10 | PHGDH | PHGDH Entrez, Source | phosphoglycerate dehydrogenase | 12681 | -0.071 | -0.5623 | No |
| 11 | TMC6 | TMC6 Entrez, Source | transmembrane channel-like 6 | 12912 | -0.081 | -0.5707 | No |
| 12 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 12980 | -0.084 | -0.5713 | No |
| 13 | CSTA | CSTA Entrez, Source | cystatin A (stefin A) | 13526 | -0.107 | -0.5940 | No |
| 14 | VPS37A | VPS37A Entrez, Source | vacuolar protein sorting 37 homolog A (S. cerevisiae) | 13719 | -0.117 | -0.5995 | No |
| 15 | EIF4EBP1 | EIF4EBP1 Entrez, Source | eukaryotic translation initiation factor 4E binding protein 1 | 13962 | -0.131 | -0.6070 | No |
| 16 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 13991 | -0.132 | -0.6042 | No |
| 17 | BGLAP | BGLAP Entrez, Source | bone gamma-carboxyglutamate (gla) protein (osteocalcin) | 14117 | -0.139 | -0.6058 | No |
| 18 | NSUN7 | NSUN7 Entrez, Source | NOL1/NOP2/Sun domain family, member 7 | 14968 | -0.201 | -0.6401 | No |
| 19 | RAB33A | RAB33A Entrez, Source | RAB33A, member RAS oncogene family | 15164 | -0.218 | -0.6427 | No |
| 20 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 16004 | -0.306 | -0.6732 | Yes |
| 21 | MFAP4 | MFAP4 Entrez, Source | microfibrillar-associated protein 4 | 16108 | -0.320 | -0.6681 | Yes |
| 22 | STC2 | STC2 Entrez, Source | stanniocalcin 2 | 16239 | -0.339 | -0.6638 | Yes |
| 23 | GPT2 | GPT2 Entrez, Source | glutamic pyruvate transaminase (alanine aminotransferase) 2 | 16415 | -0.364 | -0.6608 | Yes |
| 24 | ZNF70 | ZNF70 Entrez, Source | zinc finger protein 70 | 16692 | -0.406 | -0.6613 | Yes |
| 25 | CTH | CTH Entrez, Source | cystathionase (cystathionine gamma-lyase) | 17055 | -0.474 | -0.6638 | Yes |
| 26 | SESN2 | SESN2 Entrez, Source | sestrin 2 | 17067 | -0.476 | -0.6495 | Yes |
| 27 | PCK2 | PCK2 Entrez, Source | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 17238 | -0.520 | -0.6415 | Yes |
| 28 | SLC7A11 | SLC7A11 Entrez, Source | solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 | 18086 | -0.753 | -0.6584 | Yes |
| 29 | CEBPB | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 18189 | -0.783 | -0.6389 | Yes |
| 30 | CLEC2D | CLEC2D Entrez, Source | C-type lectin domain family 2, member D | 18318 | -0.833 | -0.6191 | Yes |
| 31 | TMC8 | TMC8 Entrez, Source | transmembrane channel-like 8 | 18418 | -0.863 | -0.5969 | Yes |
| 32 | TRIB3 | TRIB3 Entrez, Source | tribbles homolog 3 (Drosophila) | 18863 | -1.057 | -0.5852 | Yes |
| 33 | KLHL4 | KLHL4 Entrez, Source | kelch-like 4 (Drosophila) | 19049 | -1.148 | -0.5582 | Yes |
| 34 | PTGER2 | PTGER2 Entrez, Source | prostaglandin E receptor 2 (subtype EP2), 53kDa | 19054 | -1.151 | -0.5226 | Yes |
| 35 | INHBE | INHBE Entrez, Source | inhibin, beta E | 19241 | -1.250 | -0.4925 | Yes |
| 36 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 19324 | -1.292 | -0.4562 | Yes |
| 37 | BATF3 | 19983 | -1.848 | -0.4300 | Yes | ||
| 38 | ALPK2 | ALPK2 Entrez, Source | alpha-kinase 2 | 20668 | -3.139 | -0.3648 | Yes |
| 39 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 20767 | -3.579 | -0.2580 | Yes |
| 40 | ASB2 | ASB2 Entrez, Source | ankyrin repeat and SOCS box-containing 2 | 20780 | -3.653 | -0.1447 | Yes |
| 41 | TM6SF1 | TM6SF1 Entrez, Source | transmembrane 6 superfamily member 1 | 20924 | -4.967 | 0.0032 | Yes |
