Details for gene set FORTSCHEGGER_PHF8_TARGETS_UP[GSEA]

Table: GSEA Results Summary

Dataset	NS50832_padj
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	FORTSCHEGGER_PHF8_TARGETS_UP
Enrichment Score (ES)	-0.71210164
Normalized Enrichment Score (NES)	-1.6932075
Nominal p-value	0.0
FDR q-value	0.17979105
FWER p-Value	0.984

Fig 1: Enrichment plot: FORTSCHEGGER_PHF8_TARGETS_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FZD5			38	109.643	0.0297	No
2	CITED2			143	54.021	0.0410	No
3	FZD7			200	40.889	0.0505	No
4	LRP8			208	39.535	0.0614	No
5	VTI1B			293	30.294	0.0668	No
6	CMTM7			365	25.490	0.0713	No
7	ARL6IP1			472	21.533	0.0733	No
8	C6orf62			723	15.826	0.0682	No
9	FUBP1			847	14.067	0.0675	No
10	ADAMTS1			922	13.023	0.0684	No
11	DHRS3			933	12.896	0.0717	No
12	NQO2			988	12.307	0.0731	No
13	KPNB1			995	12.236	0.0763	No
14	MGAT5			1043	11.670	0.0778	No
15	SCD			1102	11.098	0.0787	No
16	ZNF76			1176	10.523	0.0789	No
17	IQCG			1214	10.268	0.0804	No
18	KLHL7			1246	9.949	0.0821	No
19	IVNS1ABP			1265	9.846	0.0842	No
20	RAB8A			1273	9.818	0.0867	No
21	FKBP1A			1342	9.289	0.0867	No
22	BCL2L11			1528	8.185	0.0819	No
23	MOCS2			1563	7.960	0.0829	No
24	TFPI			1640	7.533	0.0821	No
25	TUSC2			1654	7.495	0.0837	No
26	VAMP1			1711	7.211	0.0836	No
27	NKAIN1			1725	7.159	0.0852	No
28	TGFBR2			1740	7.119	0.0867	No
29	PABPN1			1810	6.770	0.0859	No
30	GRAMD1B			2042	5.911	0.0788	No
31	CTSC			2055	5.878	0.0800	No
32	IGF1R			2148	5.588	0.0780	No
33	PTP4A1			2168	5.519	0.0789	No
34	CERK			2493	4.644	0.0678	No
35	RPIA			2593	4.443	0.0652	No
36	FAM171A1			2617	4.377	0.0656	No
37	FAM105A			2637	4.337	0.0661	No
38	CDH24			2648	4.308	0.0669	No
39	GCLC			2659	4.289	0.0678	No
40	INSR			2697	4.181	0.0675	No
41	STEAP3			2717	4.149	0.0680	No
42	SYNCRIP			2873	3.833	0.0631	No
43	CDC26			2882	3.820	0.0639	No
44	ITPR1			2995	3.635	0.0606	No
45	HMOX1			3141	3.368	0.0560	No
46	MIR17HG			3274	3.178	0.0519	No
47	ATF4			3319	3.105	0.0511	No
48	ACVR2B			3393	3.001	0.0491	No
49	FAM173B			3522	2.829	0.0450	No
50	GSK3B			3658	2.696	0.0406	No
51	C9orf116			3667	2.689	0.0410	No
52	ZP3			3845	2.475	0.0350	No
53	FZD10			4037	2.285	0.0283	No
54	CENPV			4128	2.195	0.0255	No
55	MCF2L			4257	2.058	0.0211	No
56	CALU			4369	1.958	0.0174	No
57	MAT2B			4462	1.872	0.0144	No
58	PABPC4			4481	1.862	0.0143	No
59	RCOR3			4723	1.675	0.0055	No
60	YKT6			4922	1.531	-0.0017	No
61	TSPAN13			4975	1.491	-0.0032	No
62	HLX			5146	1.381	-0.0094	No
63	IQCK			5285	1.307	-0.0143	No
64	ARHGAP28			5312	1.285	-0.0149	No
65	PDGFC			5424	1.228	-0.0188	No
66	FBXW7			5460	1.204	-0.0198	No
67	DPCD			5572	1.136	-0.0238	No
68	CHML			5695	1.069	-0.0281	No
69	ACPP			5847	0.991	-0.0336	No
70	SET			5935	0.954	-0.0367	No
71	RASD1			6115	0.890	-0.0433	No
72	XYLT2			6249	0.839	-0.0482	No
73	FAM120C			6268	0.834	-0.0486	No
74	CBX8			6304	0.823	-0.0497	No
75	RNLS			6427	0.786	-0.0542	No
76	JAG2			6456	0.776	-0.0551	No
77	TBC1D4			6526	0.754	-0.0575	No
78	PTPN2			6643	0.712	-0.0617	No
79	DCBLD1			6740	0.673	-0.0652	No
80	SLC19A2			6796	0.660	-0.0671	No
81	GPR180			7261	0.536	-0.0848	No
82	CNOT6			7450	0.498	-0.0919	No
83	NLN			7555	0.474	-0.0957	No
84	CLN3			7582	0.466	-0.0966	No
85	ID1			7629	0.457	-0.0982	No
86	TSPAN3			7636	0.456	-0.0983	No
87	DUSP2			7799	0.427	-0.1044	No
88	ATF4P3			7872	0.417	-0.1070	No
89	UCP3			8630	0.305	-0.1360	No
90	MND1			8687	0.299	-0.1381	No
91	KLHL15			8831	0.280	-0.1435	No
92	KCNK3			8877	0.274	-0.1451	No
93	CALML4			8889	0.273	-0.1454	No
94	C11orf57			8922	0.269	-0.1466	No
95	FNBP1L			9119	0.247	-0.1540	No
96	NEK10			9338	0.222	-0.1623	No
97	NQO1			9499	0.207	-0.1684	No
98	SLC16A1			9606	0.195	-0.1724	No
99	NEK4			9830	0.176	-0.1809	No
100	BMP6			9894	0.171	-0.1833	No
101	KLRG1			11244	0.080	-0.2350	No
102	PTGES2			11447	0.068	-0.2427	No
103	SERF1B			11505	0.065	-0.2449	No
104	CRB1			11609	0.060	-0.2488	No
105	RELL1			11680	0.056	-0.2515	No
106	DDX3X			11986	0.044	-0.2632	No
107	SPA17			12376	0.027	-0.2781	No
108	RASSF9			12435	0.025	-0.2803	No
109	SMC5			12541	0.021	-0.2843	No
110	FBXW10			12696	0.015	-0.2902	No
111	LYG1			12883	0.007	-0.2974	No
112	NFYB			12995	0.005	-0.3016	No
113	KRTDAP			13237	-0.004	-0.3109	No
114	TCP10L			13769	-0.023	-0.3312	No
115	HBP1			13784	-0.023	-0.3318	No
116	PDK4			13791	-0.024	-0.3320	No
117	XIAP			14046	-0.034	-0.3417	No
118	CCNYL1			14301	-0.044	-0.3514	No
119	CCNY			14406	-0.048	-0.3554	No
120	PDE1A			14543	-0.052	-0.3606	No
121	ZG16B			14580	-0.053	-0.3620	No
122	WWP1			15138	-0.081	-0.3833	No
123	HMGB2			15209	-0.085	-0.3860	No
124	LYRM7			15279	-0.088	-0.3886	No
125	CDC37L1			15503	-0.102	-0.3971	No
126	TNPO1			15597	-0.108	-0.4007	No
127	MRRF			16093	-0.140	-0.4196	No
128	OSCP1			16145	-0.144	-0.4215	No
129	MCM3AP-AS1			16270	-0.152	-0.4262	No
130	NR0B1			16431	-0.164	-0.4323	No
131	MOK			16452	-0.166	-0.4330	No
132	FAM60A			16563	-0.175	-0.4372	No
133	A2M			16583	-0.178	-0.4379	No
134	RNF141			16632	-0.183	-0.4397	No
135	BNIP2			16702	-0.189	-0.4423	No
136	LZTFL1			16900	-0.208	-0.4498	No
137	ENAH			16954	-0.213	-0.4517	No
138	RIMS4			17054	-0.223	-0.4555	No
139	CBX5			17102	-0.230	-0.4572	No
140	TCTEX1D2			17263	-0.245	-0.4633	No
141	TMTC4			17489	-0.274	-0.4718	No
142	YES1			17492	-0.274	-0.4718	No
143	LIN9			17505	-0.275	-0.4722	No
144	SLC2A3			18053	-0.342	-0.4931	No
145	SUZ12			18093	-0.347	-0.4945	No
146	DCAF17			18266	-0.375	-0.5010	No
147	HEY1			18340	-0.387	-0.5037	No
148	GABPB1			18483	-0.413	-0.5090	No
149	PTPRJ			18542	-0.424	-0.5111	No
150	PDHX			18835	-0.480	-0.5222	No
151	ECM2			18915	-0.498	-0.5251	No
152	AKR1C1			19331	-0.586	-0.5408	No
153	MAN1A1			19387	-0.603	-0.5427	No
154	CCDC6			19444	-0.616	-0.5447	No
155	TFPI2			19448	-0.618	-0.5447	No
156	MBTD1			19495	-0.629	-0.5462	No
157	SEC62			19620	-0.664	-0.5508	No
158	RASA4			19832	-0.731	-0.5587	No
159	RBM33			19846	-0.733	-0.5590	No
160	DNAJB4			19862	-0.738	-0.5593	No
161	ECE1			20039	-0.794	-0.5659	No
162	TMEM79			20100	-0.811	-0.5679	No
163	SLC16A6			20442	-0.938	-0.5808	No
164	TNFRSF11B			20444	-0.938	-0.5805	No
165	STX6			20551	-0.981	-0.5843	No
166	SORBS2			20831	-1.108	-0.5947	No
167	BET1			20912	-1.144	-0.5974	No
168	DPY19L4			21056	-1.226	-0.6026	No
169	FAM86C1			21238	-1.332	-0.6091	No
170	TPCN1			21306	-1.366	-0.6113	No
171	PIAS2			21474	-1.471	-0.6173	No
172	SYT15			21506	-1.488	-0.6181	No
173	ZNF721			21519	-1.494	-0.6181	No
174	RAB10			21628	-1.564	-0.6218	No
175	TOP2B			21868	-1.742	-0.6305	No
176	SSU72			21877	-1.748	-0.6303	No
177	BID			22004	-1.869	-0.6346	No
178	SERF1A			22007	-1.872	-0.6341	No
179	SETD4			22251	-2.078	-0.6429	No
180	LINC00116			22495	-2.324	-0.6515	No
181	MRPL42			22541	-2.367	-0.6526	No
182	MLXIPL			22964	-2.895	-0.6679	No
183	ANKRD46			23064	-3.030	-0.6709	No
184	JMY			23274	-3.370	-0.6779	No
185	SERP1			23293	-3.403	-0.6777	No
186	ZNF280C			23303	-3.423	-0.6770	No
187	PDE4D			23393	-3.607	-0.6794	No
188	VAV3			23486	-3.765	-0.6819	No
189	EIF2AK4			23487	-3.765	-0.6808	No
190	NMNAT1			23557	-3.917	-0.6824	No
191	TMEM116			23609	-4.020	-0.6832	No
192	GABPB2			23614	-4.040	-0.6822	No
193	RERG			23653	-4.122	-0.6825	No
194	CCDC77			23665	-4.142	-0.6817	No
195	FAM86B1			23843	-4.575	-0.6872	No
196	ZNF267			24029	-5.126	-0.6928	No
197	RBKS			24139	-5.407	-0.6955	No
198	EFNA1			24176	-5.516	-0.6953	No
199	PHGDH			24203	-5.598	-0.6947	No
200	PCSK1			24286	-5.940	-0.6962	No
201	KLF9			24326	-6.110	-0.6959	No
202	DCAF4			24371	-6.276	-0.6958	No
203	NSRP1			24581	-7.143	-0.7018	No
204	RIMKLB			24690	-7.610	-0.7038	No
205	EIF5			24866	-8.648	-0.7081	No
206	NUPR1			24923	-9.037	-0.7077	No
207	HTRA3			25040	-10.089	-0.7092	Yes
208	GKAP1			25111	-10.682	-0.7089	Yes
209	TIPIN			25187	-11.436	-0.7085	Yes
210	MAP2			25191	-11.477	-0.7054	Yes
211	HINT3			25192	-11.494	-0.7021	Yes
212	E2F5			25198	-11.551	-0.6990	Yes
213	BMP2			25202	-11.606	-0.6959	Yes
214	DDAH1			25308	-12.795	-0.6963	Yes
215	MAP7			25471	-14.937	-0.6982	Yes
216	NPTX1			25528	-15.889	-0.6959	Yes
217	STOX2			25537	-16.055	-0.6916	Yes
218	LMO4			25682	-19.607	-0.6916	Yes
219	LINC00467			25724	-20.696	-0.6873	Yes
220	CTGF			25736	-21.035	-0.6817	Yes
221	PYCR1			25769	-21.972	-0.6767	Yes
222	NCOA7			25853	-25.364	-0.6727	Yes
223	SGPL1			25871	-25.891	-0.6660	Yes
224	GRB10			25941	-30.158	-0.6601	Yes
225	NR4A1			25994	-33.453	-0.6526	Yes
226	IL20RB			26119	-46.747	-0.6441	Yes
227	SLC7A11			26126	-47.089	-0.6310	Yes
228	KRCC1			26142	-50.080	-0.6173	Yes
229	HERPUD1			26159	-53.015	-0.6029	Yes
230	VLDLR			26190	-59.843	-0.5871	Yes
231	DUSP16			26195	-61.523	-0.5697	Yes
232	ASNS			26241	-83.978	-0.5476	Yes
233	VEGFA			26251	-89.987	-0.5224	Yes
234	MTHFD2			26257	-95.222	-0.4956	Yes
235	STC2			26260	-97.527	-0.4680	Yes
236	SESN2			26273	-109.055	-0.4375	Yes
237	GPT2			26276	-117.291	-0.4043	Yes
238	ALDH1L2			26287	-152.864	-0.3613	Yes
239	TXNIP			26293	-180.286	-0.3104	Yes
240	PCK2			26298	-198.705	-0.2541	Yes
241	DDIT4			26311	-299.207	-0.1697	Yes
242	INHBE			26312	-299.207	-0.0848	Yes
243	CHAC1			26314	-299.207	0.0001	Yes

Fig 2: FORTSCHEGGER_PHF8_TARGETS_UP: Random ES distribution   
Gene set null distribution of ES for FORTSCHEGGER_PHF8_TARGETS_UP