Details for gene set GO_DNA_INTEGRITY_CHECKPOINT[GSEA]

Table: GSEA Results Summary

Dataset	NS50832_padj
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	GO_DNA_INTEGRITY_CHECKPOINT
Enrichment Score (ES)	0.7433703
Normalized Enrichment Score (NES)	1.7408638
Nominal p-value	0.0
FDR q-value	0.13890655
FWER p-Value	0.748

Fig 1: Enrichment plot: GO_DNA_INTEGRITY_CHECKPOINT   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CDKN1A			2	299.207	0.2341	Yes
2	RPS27L			40	106.999	0.3165	Yes
3	BAX			53	95.755	0.3910	Yes
4	BTG2			60	90.877	0.4619	Yes
5	MDM2			156	51.042	0.4982	Yes
6	XPC			204	40.284	0.5280	Yes
7	TRIAP1			239	35.685	0.5546	Yes
8	PCNA			255	34.423	0.5810	Yes
9	CCNB1			387	24.655	0.5953	Yes
10	GTSE1			394	24.176	0.6140	Yes
11	TAOK2			436	22.598	0.6301	Yes
12	PLK2			461	21.783	0.6462	Yes
13	SFN			603	18.262	0.6551	Yes
14	RBM38			652	17.278	0.6668	Yes
15	CDK1			676	16.831	0.6791	Yes
16	PLK3			703	16.241	0.6909	Yes
17	CASP2			802	14.851	0.6987	Yes
18	E2F7			830	14.296	0.7089	Yes
19	CLSPN			837	14.160	0.7198	Yes
20	CRADD			1008	11.968	0.7226	Yes
21	FOXO4			1024	11.812	0.7313	Yes
22	CCNA2			1369	9.062	0.7253	Yes
23	RFWD3			1438	8.664	0.7294	Yes
24	FBXO31			1619	7.654	0.7286	Yes
25	PRMT1			1642	7.527	0.7336	Yes
26	PLK5			1656	7.491	0.7390	Yes
27	SOX4			1692	7.315	0.7434	Yes
28	E2F4			2009	6.019	0.7360	No
29	FZR1			2134	5.623	0.7357	No
30	HMGA2			2268	5.208	0.7347	No
31	FOXN3			2329	5.023	0.7363	No
32	H2AFX			2342	5.007	0.7398	No
33	GIGYF2			2422	4.780	0.7405	No
34	TP73			2507	4.622	0.7409	No
35	DNA2			2588	4.453	0.7413	No
36	HUS1			2636	4.337	0.7429	No
37	CDK2			2749	4.087	0.7419	No
38	CENPJ			2831	3.907	0.7418	No
39	CDC5L			2965	3.669	0.7396	No
40	ZNF385A			3164	3.340	0.7347	No
41	UBB			3255	3.201	0.7337	No
42	CCND1			3538	2.814	0.7252	No
43	UBA52			3612	2.746	0.7245	No
44	CDT1			3730	2.593	0.7221	No
45	CNOT8			4010	2.306	0.7133	No
46	MDC1			4291	2.024	0.7041	No
47	BRIP1			4466	1.870	0.6990	No
48	PRPF19			4748	1.654	0.6895	No
49	ARID3A			4941	1.515	0.6834	No
50	E2F1			4963	1.500	0.6838	No
51	PML			5388	1.243	0.6685	No
52	ATRIP			5547	1.148	0.6634	No
53	CARM1			5636	1.100	0.6609	No
54	MAPK14			5854	0.987	0.6534	No
55	TOP2A			6015	0.925	0.6480	No
56	MAPKAPK2			6284	0.828	0.6384	No
57	USP28			6433	0.783	0.6334	No
58	AURKA			6451	0.778	0.6333	No
59	ATR			6563	0.740	0.6297	No
60	NAE1			6621	0.718	0.6281	No
61	TFDP2			6940	0.619	0.6164	No
62	SYF2			7031	0.593	0.6134	No
63	CDK5RAP3			7133	0.567	0.6100	No
64	CNOT6			7450	0.498	0.5983	No
65	EP300			7882	0.416	0.5822	No
66	CDC45			7930	0.407	0.5807	No
67	RPS27A			7967	0.401	0.5797	No
68	NPM1			8001	0.394	0.5787	No
69	ZNF830			8127	0.376	0.5742	No
70	HUS1B			8191	0.368	0.5721	No
71	CHEK2			8686	0.299	0.5535	No
72	UBC			8798	0.286	0.5495	No
73	PRKDC			8863	0.276	0.5472	No
74	BABAM1			9273	0.230	0.5318	No
75	HINFP			9985	0.164	0.5048	No
76	BLM			10670	0.112	0.4787	No
77	TP53BP1			10962	0.094	0.4677	No
78	TNKS1BP1			11231	0.081	0.4575	No
79	UIMC1			11507	0.064	0.4471	No
80	GADD45A			11891	0.047	0.4325	No
81	CNOT1			12196	0.035	0.4209	No
82	CNOT2			12436	0.025	0.4118	No
83	TAOK1			12447	0.025	0.4114	No
84	NEK11			12948	0.006	0.3923	No
85	MDM4			13001	0.005	0.3904	No
86	CDC6			14100	-0.035	0.3485	No
87	CHEK1			14125	-0.037	0.3476	No
88	PLAGL1			14158	-0.039	0.3464	No
89	PLK1			14929	-0.069	0.3170	No
90	PTPN11			15070	-0.077	0.3117	No
91	RPA4			15568	-0.106	0.2928	No
92	ATF2			15697	-0.113	0.2880	No
93	PPP2R5C			15792	-0.120	0.2845	No
94	CLOCK			15875	-0.124	0.2815	No
95	BRSK1			15884	-0.125	0.2813	No
96	TIPRL			16037	-0.137	0.2756	No
97	ATM			16808	-0.200	0.2464	No
98	CEP63			16849	-0.204	0.2450	No
99	SETMAR			17845	-0.316	0.2072	No
100	RAD9B			18061	-0.343	0.1993	No
101	CNOT3			18104	-0.349	0.1980	No
102	BRCC3			18355	-0.390	0.1887	No
103	CNOT4			18759	-0.466	0.1737	No
104	DGKZ			18924	-0.501	0.1678	No
105	DTL			19534	-0.643	0.1451	No
106	FBXO6			19992	-0.782	0.1282	No
107	INTS7			20316	-0.889	0.1166	No
108	CNOT10			20323	-0.892	0.1171	No
109	CNOT7			20626	-1.009	0.1063	No
110	FANCI			20836	-1.109	0.0992	No
111	CDC14B			21365	-1.401	0.0801	No
112	TOP2B			21868	-1.742	0.0623	No
113	CDC25C			22485	-2.318	0.0406	No
114	RPA2			22655	-2.518	0.0361	No
115	RAD1			22732	-2.597	0.0353	No
116	BRCA1			23247	-3.326	0.0182	No
117	CDKN1B			23273	-3.364	0.0199	No
118	TFDP1			23324	-3.462	0.0207	No
119	RBL2			23437	-3.679	0.0193	No
120	PEA15			23464	-3.719	0.0212	No
121	NEK6			23573	-3.949	0.0202	No
122	NBN			23844	-4.578	0.0135	No
123	MUC1			24081	-5.263	0.0086	No
124	RBBP8			24369	-6.275	0.0025	No
125	RAD17			24393	-6.352	0.0066	No
126	CNOT6L			24555	-7.042	0.0060	No
127	RAD9A			24579	-7.142	0.0107	No
128	MSH2			24778	-8.121	0.0095	No
129	TAOK3			24789	-8.188	0.0155	No
130	TIPIN			25187	-11.436	0.0093	No
131	TP53			25300	-12.686	0.0150	No
132	PCBP4			25454	-14.763	0.0207	No
133	WAC			25513	-15.622	0.0307	No

Fig 2: GO_DNA_INTEGRITY_CHECKPOINT: Random ES distribution   
Gene set null distribution of ES for GO_DNA_INTEGRITY_CHECKPOINT