Details for gene set GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS[GSEA]

Table: GSEA Results Summary

Dataset	NS50832_padj
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS
Enrichment Score (ES)	0.6906232
Normalized Enrichment Score (NES)	1.7274635
Nominal p-value	0.0
FDR q-value	0.13843632
FWER p-Value	0.873

Fig 1: Enrichment plot: GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	HSPA8			56	93.481	0.0651	Yes
2	HNRNPH2			181	43.748	0.0918	Yes
3	SRSF2			209	39.532	0.1192	Yes
4	SF3B3			241	35.554	0.1436	Yes
5	DDX23			251	34.799	0.1683	Yes
6	GEMIN4			272	32.385	0.1908	Yes
7	DHX9			284	31.114	0.2128	Yes
8	PPIL3			298	30.009	0.2338	Yes
9	PRMT7			303	29.142	0.2547	Yes
10	HNRNPA0			315	28.324	0.2746	Yes
11	LSM3			500	20.523	0.2823	Yes
12	WDR77			510	20.322	0.2966	Yes
13	SF3A3			531	19.740	0.3100	Yes
14	SRRT			567	18.978	0.3223	Yes
15	LSM7			578	18.704	0.3354	Yes
16	DDX39A			596	18.368	0.3480	Yes
17	METTL3			614	17.969	0.3602	Yes
18	PRPF4			674	16.853	0.3701	Yes
19	SF3A1			683	16.727	0.3818	Yes
20	CLP1			705	16.207	0.3927	Yes
21	SF3B5			713	16.039	0.4039	Yes
22	HNRNPF			741	15.597	0.4141	Yes
23	CELF3			742	15.583	0.4253	Yes
24	HNRNPR			762	15.243	0.4356	Yes
25	POLR2L			794	14.910	0.4451	Yes
26	SF3B4			806	14.791	0.4553	Yes
27	PRPF4B			815	14.621	0.4655	Yes
28	PRPF8			893	13.479	0.4723	Yes
29	DHX8			993	12.251	0.4773	Yes
30	SNRPG			1076	11.321	0.4823	Yes
31	PTBP2			1087	11.193	0.4899	Yes
32	SETX			1137	10.843	0.4959	Yes
33	RBM15			1160	10.669	0.5027	Yes
34	CD2BP2			1247	9.937	0.5065	Yes
35	TGS1			1254	9.898	0.5134	Yes
36	PCBP1			1275	9.813	0.5197	Yes
37	DHX15			1302	9.631	0.5256	Yes
38	SRRM1			1315	9.525	0.5320	Yes
39	PTBP1			1323	9.452	0.5386	Yes
40	SART3			1354	9.199	0.5440	Yes
41	SRRM2			1363	9.105	0.5503	Yes
42	FUS			1383	8.968	0.5560	Yes
43	CSTF3			1487	8.356	0.5581	Yes
44	HNRNPK			1495	8.323	0.5638	Yes
45	CPSF1			1497	8.302	0.5697	Yes
46	SNRPD3			1578	7.869	0.5723	Yes
47	U2AF2			1594	7.772	0.5773	Yes
48	SRSF5			1652	7.498	0.5805	Yes
49	PHF5A			1696	7.286	0.5841	Yes
50	SNRPD2			1742	7.092	0.5875	Yes
51	TFIP11			1743	7.091	0.5926	Yes
52	HNRNPA2B1			1777	6.941	0.5963	Yes
53	RAVER1			1781	6.916	0.6012	Yes
54	HNRNPA1			1787	6.889	0.6059	Yes
55	PABPN1			1810	6.770	0.6100	Yes
56	SNRNP25			1838	6.703	0.6137	Yes
57	SF1			1892	6.431	0.6163	Yes
58	SNRPE			1908	6.371	0.6203	Yes
59	DQX1			1936	6.251	0.6238	Yes
60	CCAR1			1945	6.231	0.6280	Yes
61	HNRNPD			1950	6.218	0.6323	Yes
62	WBP11			1968	6.167	0.6361	Yes
63	RBMX			2025	5.955	0.6382	Yes
64	SNRPF			2066	5.846	0.6409	Yes
65	POLR2H			2080	5.778	0.6446	Yes
66	NOVA2			2090	5.749	0.6483	Yes
67	HNRNPU			2093	5.744	0.6524	Yes
68	DDX46			2117	5.668	0.6556	Yes
69	HNRNPUL1			2169	5.509	0.6576	Yes
70	PRPF31			2187	5.438	0.6609	Yes
71	RBMXL1			2188	5.437	0.6648	Yes
72	GPATCH1			2239	5.284	0.6666	Yes
73	EFTUD2			2305	5.091	0.6678	Yes
74	HNRNPA3			2318	5.038	0.6710	Yes
75	DNAJC8			2433	4.759	0.6700	Yes
76	SNRPD1			2610	4.392	0.6664	Yes
77	EIF4A3			2614	4.386	0.6695	Yes
78	SNRNP200			2630	4.347	0.6720	Yes
79	NAA38			2723	4.142	0.6715	Yes
80	SNRNP40			2759	4.057	0.6731	Yes
81	GEMIN6			2760	4.053	0.6760	Yes
82	POLR2D			2792	3.992	0.6776	Yes
83	SF3A2			2795	3.979	0.6804	Yes
84	LUC7L3			2801	3.972	0.6831	Yes
85	SYNCRIP			2873	3.833	0.6831	Yes
86	DDX5			2900	3.787	0.6849	Yes
87	HNRNPM			2925	3.750	0.6866	Yes
88	CDC5L			2965	3.669	0.6878	Yes
89	NCBP2			3014	3.587	0.6885	Yes
90	SRSF1			3027	3.569	0.6906	Yes
91	CASC3			3132	3.375	0.6891	No
92	POLR2K			3226	3.236	0.6878	No
93	LSM6			3296	3.144	0.6874	No
94	HNRNPL			3634	2.724	0.6765	No
95	CSTF1			3735	2.588	0.6745	No
96	SNRNP70			3772	2.560	0.6749	No
97	USP49			3793	2.534	0.6760	No
98	SRSF6			3805	2.524	0.6774	No
99	ZMAT5			3818	2.512	0.6787	No
100	MPHOSPH10			3850	2.466	0.6793	No
101	CELF1			3869	2.448	0.6804	No
102	MAGOH			4005	2.314	0.6769	No
103	HNRNPH1			4053	2.260	0.6767	No
104	USP4			4144	2.171	0.6748	No
105	PRPF40A			4277	2.035	0.6712	No
106	SNRPB			4336	1.985	0.6704	No
107	ISY1			4403	1.927	0.6693	No
108	SRSF9			4444	1.892	0.6691	No
109	CRNKL1			4460	1.874	0.6699	No
110	LUC7L			4533	1.826	0.6684	No
111	ELAVL1			4649	1.739	0.6653	No
112	PRPF39			4687	1.702	0.6651	No
113	PRPF19			4748	1.654	0.6640	No
114	ZMAT2			4761	1.648	0.6647	No
115	AQR			4843	1.593	0.6627	No
116	GEMIN5			4873	1.567	0.6627	No
117	DBR1			4878	1.559	0.6637	No
118	PABPC1			4895	1.550	0.6642	No
119	SF3B1			4902	1.545	0.6651	No
120	ZCRB1			4918	1.535	0.6656	No
121	SNRPB2			4936	1.523	0.6661	No
122	LUC7L2			4965	1.498	0.6661	No
123	SF3B2			4967	1.495	0.6671	No
124	LSM1			4986	1.483	0.6675	No
125	POLR2B			5113	1.400	0.6636	No
126	PNN			5202	1.352	0.6612	No
127	CPSF7			5222	1.342	0.6615	No
128	PRMT5			5247	1.327	0.6615	No
129	CWC15			5299	1.295	0.6605	No
130	SRSF11			5315	1.283	0.6608	No
131	SRSF3			5380	1.246	0.6593	No
132	LSM2			5438	1.216	0.6580	No
133	SPEN			5498	1.178	0.6565	No
134	RALY			5504	1.175	0.6572	No
135	XAB2			5534	1.158	0.6569	No
136	GEMIN8			5538	1.154	0.6576	No
137	NONO			5669	1.083	0.6534	No
138	NCBP1			5753	1.042	0.6510	No
139	UBL5			5838	0.996	0.6485	No
140	SNRPC			5858	0.985	0.6485	No
141	LSM4			5982	0.937	0.6444	No
142	PAPOLA			6073	0.906	0.6416	No
143	PQBP1			6198	0.859	0.6375	No
144	PPIH			6301	0.824	0.6342	No
145	KHSRP			6364	0.803	0.6324	No
146	GPKOW			6408	0.790	0.6313	No
147	DHX35			6576	0.734	0.6254	No
148	SNRNP35			6715	0.680	0.6206	No
149	DDX20			6887	0.635	0.6145	No
150	FRG1			6976	0.611	0.6115	No
151	SYF2			7031	0.593	0.6099	No
152	CDK13			7033	0.593	0.6103	No
153	RNPC3			7132	0.567	0.6069	No
154	POLR2I			7137	0.567	0.6072	No
155	POLR2E			7163	0.559	0.6066	No
156	PRPF6			7470	0.492	0.5952	No
157	NUDT21			7664	0.453	0.5882	No
158	SCAF11			7917	0.410	0.5788	No
159	METTL14			8118	0.377	0.5714	No
160	SNUPN			8247	0.361	0.5667	No
161	PRPF3			8293	0.356	0.5653	No
162	BUD13			8672	0.302	0.5510	No
163	LSM5			8837	0.280	0.5449	No
164	USP39			9082	0.251	0.5357	No
165	TXNL4A			9200	0.240	0.5314	No
166	RBM22			9212	0.238	0.5311	No
167	HNRNPC			9576	0.199	0.5174	No
168	POLR2A			9610	0.195	0.5162	No
169	SRSF7			9632	0.194	0.5156	No
170	RNPS1			9851	0.174	0.5073	No
171	DDX41			9900	0.171	0.5056	No
172	DDX39B			10147	0.149	0.4963	No
173	SRSF10			10436	0.129	0.4853	No
174	PRPF18			10906	0.097	0.4674	No
175	DHX38			10937	0.096	0.4663	No
176	CSTF2			11238	0.080	0.4549	No
177	SNRPA1			11250	0.079	0.4545	No
178	DHX16			11296	0.076	0.4528	No
179	HELB			11333	0.075	0.4515	No
180	RSRC1			11687	0.056	0.4380	No
181	CPSF3			11693	0.056	0.4378	No
182	SLU7			11832	0.049	0.4326	No
183	SMNDC1			11943	0.046	0.4284	No
184	SRSF4			12189	0.035	0.4190	No
185	HNRNPH3			12257	0.033	0.4165	No
186	PCF11			12469	0.023	0.4084	No
187	YBX1			12479	0.023	0.4081	No
188	CWC22			12703	0.014	0.3995	No
189	SMN1			12775	0.011	0.3968	No
190	CTNNBL1			13487	-0.012	0.3695	No
191	RBMX2			13513	-0.013	0.3686	No
192	POLR2C			13625	-0.017	0.3643	No
193	U2AF1L4			14482	-0.051	0.3315	No
194	PPIL1			14730	-0.059	0.3221	No
195	RBM17			14845	-0.063	0.3178	No
196	HTATSF1			14988	-0.072	0.3124	No
197	PSIP1			16206	-0.148	0.2658	No
198	TRA2B			16371	-0.158	0.2596	No
199	PPIE			17126	-0.233	0.2309	No
200	GTF2F2			17349	-0.256	0.2225	No
201	RBM8A			17446	-0.269	0.2190	No
202	DCPS			17675	-0.295	0.2105	No
203	SFPQ			17819	-0.312	0.2052	No
204	RNF113A			17860	-0.318	0.2039	No
205	WBP4			18035	-0.340	0.1975	No
206	SART1			18238	-0.370	0.1900	No
207	STRAP			18888	-0.490	0.1655	No
208	WDR83			19043	-0.522	0.1599	No
209	SFSWAP			19057	-0.525	0.1598	No
210	POLR2J			19513	-0.634	0.1428	No
211	NOL3			19916	-0.755	0.1279	No
212	PDCD7			19955	-0.769	0.1270	No
213	SNRPN			20021	-0.789	0.1251	No
214	SNW1			20112	-0.815	0.1222	No
215	SRSF12			20296	-0.883	0.1158	No
216	UPF3B			20527	-0.972	0.1077	No
217	GTF2F1			20619	-1.008	0.1049	No
218	DDX1			20762	-1.072	0.1003	No
219	PRPF40B			20781	-1.081	0.1004	No
220	BCAS2			20933	-1.155	0.0954	No
221	NOVA1			20963	-1.170	0.0951	No
222	CDC40			21096	-1.247	0.0910	No
223	GEMIN2			21212	-1.316	0.0875	No
224	POLR2F			21362	-1.399	0.0828	No
225	SUGP1			21522	-1.496	0.0778	No
226	PCBP2			21541	-1.510	0.0782	No
227	PSPC1			21670	-1.593	0.0744	No
228	PPWD1			21671	-1.593	0.0755	No
229	TRA2A			21705	-1.622	0.0754	No
230	RBM41			22059	-1.911	0.0633	No
231	ZRSR2			22393	-2.211	0.0521	No
232	GEMIN7			22475	-2.310	0.0506	No
233	CELF4			22506	-2.337	0.0512	No
234	CLNS1A			22699	-2.568	0.0456	No
235	RBPMS			22810	-2.696	0.0434	No
236	SNRNP27			23028	-2.987	0.0372	No
237	ELAVL2			23107	-3.094	0.0364	No
238	BUD31			23285	-3.391	0.0321	No
239	SKIV2L2			23505	-3.784	0.0264	No
240	RAVER2			23519	-3.829	0.0286	No
241	YTHDC1			23583	-3.972	0.0291	No
242	SRPK2			23796	-4.457	0.0242	No
243	SNRNP48			23974	-4.943	0.0209	No
244	DHX32			24018	-5.093	0.0229	No
245	PLRG1			24186	-5.561	0.0205	No
246	CPSF2			24347	-6.181	0.0188	No
247	POLR2G			24446	-6.530	0.0198	No
248	TXNL4B			24501	-6.759	0.0226	No
249	CWC27			24503	-6.772	0.0274	No
250	RBM5			24534	-6.923	0.0312	No
251	FIP1L1			24561	-7.058	0.0353	No
252	SNRPA			24600	-7.237	0.0390	No
253	SMN2			24938	-9.174	0.0327	No
254	ZCCHC8			25908	-28.017	0.0157	No

Fig 2: GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS: Random ES distribution   
Gene set null distribution of ES for GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS