Details for gene set MACAEVA_PBMC_RESPONSE_TO_IR[GSEA]

Table: GSEA Results Summary

Dataset	NS50832_padj
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	MACAEVA_PBMC_RESPONSE_TO_IR
Enrichment Score (ES)	0.89796895
Normalized Enrichment Score (NES)	1.9856366
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: MACAEVA_PBMC_RESPONSE_TO_IR   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CDKN1A			2	299.207	0.1294	Yes
2	TRIM22			9	242.455	0.2341	Yes
3	EDA2R			25	129.226	0.2895	Yes
4	SESN1			29	121.516	0.3420	Yes
5	RPS27L			40	106.999	0.3879	Yes
6	BAX			53	95.755	0.4289	Yes
7	POLH			68	81.789	0.4638	Yes
8	DDB2			70	81.275	0.4989	Yes
9	ZMAT3			82	75.551	0.5312	Yes
10	TNFRSF10B			94	67.462	0.5600	Yes
11	AEN			98	66.791	0.5888	Yes
12	FDXR			106	65.175	0.6167	Yes
13	TP53INP1			107	64.094	0.6444	Yes
14	BBC3			149	52.488	0.6656	Yes
15	MDM2			156	51.042	0.6875	Yes
16	CD70			187	42.918	0.7049	Yes
17	XPC			204	40.284	0.7217	Yes
18	TRIAP1			239	35.685	0.7359	Yes
19	RAP2B			246	35.107	0.7508	Yes
20	PCNA			255	34.423	0.7654	Yes
21	EI24			260	34.262	0.7801	Yes
22	RRM2B			281	31.368	0.7929	Yes
23	TNFRSF10D			306	29.057	0.8046	Yes
24	SPATA18			325	27.585	0.8158	Yes
25	TM7SF3			354	26.007	0.8260	Yes
26	IKBIP			371	25.423	0.8364	Yes
27	PLK2			461	21.783	0.8425	Yes
28	PAPPA			533	19.686	0.8483	Yes
29	PHPT1			551	19.325	0.8560	Yes
30	DCP1B			659	17.150	0.8593	Yes
31	BRMS1L			673	16.884	0.8661	Yes
32	ASCC3			736	15.646	0.8705	Yes
33	E2F7			830	14.296	0.8732	Yes
34	LIG1			831	14.296	0.8794	Yes
35	CCNG1			836	14.184	0.8854	Yes
36	HECTD3			853	14.029	0.8908	Yes
37	PANK1			1161	10.649	0.8837	Yes
38	FBXO22			1174	10.526	0.8878	Yes
39	PPM1D			1329	9.415	0.8860	Yes
40	FAS			1372	9.028	0.8883	Yes
41	ACER2			1407	8.821	0.8909	Yes
42	SLC7A6			1489	8.350	0.8914	Yes
43	NSD1			1535	8.163	0.8932	Yes
44	CCDC90B			1548	8.076	0.8962	Yes
45	ISCU			1592	7.774	0.8980	Yes
46	TMEM30A			1783	6.901	0.8937	No
47	TMEM68			2014	5.998	0.8875	No
48	PTP4A1			2168	5.519	0.8841	No
49	ACTA2			2320	5.036	0.8805	No
50	MAP4K4			2482	4.661	0.8764	No
51	ARHGEF3			2484	4.654	0.8784	No
52	ASTN2			2496	4.643	0.8800	No
53	SOCS4			2790	3.997	0.8705	No
54	PCNP			2883	3.815	0.8687	No
55	F5			2917	3.765	0.8690	No
56	RETSAT			3069	3.503	0.8648	No
57	DNER			3305	3.131	0.8572	No
58	TRIM32			3358	3.048	0.8565	No
59	ITPR2			3436	2.943	0.8549	No
60	AMZ2			4169	2.132	0.8279	No
61	MAMDC4			4477	1.866	0.8170	No
62	FGD3			4598	1.776	0.8132	No
63	CMBL			5156	1.377	0.7925	No
64	RINL			5185	1.361	0.7921	No
65	TNFSF4			6066	0.909	0.7589	No
66	FGF10			7034	0.593	0.7223	No
67	METTL7A			9196	0.240	0.6400	No
68	ZNF79			9309	0.225	0.6359	No
69	POLR2A			9610	0.195	0.6245	No
70	GLS2			10819	0.102	0.5785	No
71	TMEM131			11691	0.056	0.5453	No
72	CPSF3			11693	0.056	0.5453	No
73	GADD45A			11891	0.047	0.5378	No
74	ZNF337			12497	0.022	0.5148	No
75	BLOC1S2			12926	0.006	0.4984	No
76	NSF			12963	0.006	0.4971	No
77	ANXA4			14971	-0.071	0.4206	No
78	ANKRA2			16458	-0.167	0.3640	No
79	LRMP			18011	-0.337	0.3050	No
80	APOBEC3H			19154	-0.546	0.2617	No
81	PTGER1			21518	-1.493	0.1723	No
82	APOBEC3C			21718	-1.633	0.1654	No
83	PRKAB1			21750	-1.651	0.1649	No
84	CDS2			21757	-1.656	0.1654	No
85	REV3L			21780	-1.669	0.1653	No
86	HIST1H3E			24353	-6.212	0.0699	No
87	DENND2D			25180	-11.367	0.0433	No

Fig 2: MACAEVA_PBMC_RESPONSE_TO_IR: Random ES distribution   
Gene set null distribution of ES for MACAEVA_PBMC_RESPONSE_TO_IR