Details for gene set TIEN_INTESTINE_PROBIOTICS_24HR_DN[GSEA]

Table: GSEA Results Summary

Dataset	NS50832_padj
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	TIEN_INTESTINE_PROBIOTICS_24HR_DN
Enrichment Score (ES)	-0.7640212
Normalized Enrichment Score (NES)	-1.7978002
Nominal p-value	0.0
FDR q-value	0.020581309
FWER p-Value	0.098

Fig 1: Enrichment plot: TIEN_INTESTINE_PROBIOTICS_24HR_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SLC6A8			55	94.569	0.0217	No
2	HSPA8			56	93.481	0.0453	No
3	HSPA5			151	52.337	0.0549	No
4	PDIA4			222	37.994	0.0618	No
5	CALR			266	32.957	0.0684	No
6	GDF15			292	30.340	0.0751	No
7	SDF2L1			350	26.338	0.0796	No
8	MANF			448	22.191	0.0814	No
9	MLPH			677	16.829	0.0769	No
10	RNF19B			823	14.447	0.0750	No
11	ACTG1			962	12.546	0.0729	No
12	PPIB			1084	11.233	0.0711	No
13	CDK2AP2			1268	9.840	0.0666	No
14	HSPH1			1350	9.216	0.0658	No
15	EIF4B			1567	7.940	0.0595	No
16	SLC35E1			1722	7.166	0.0554	No
17	UNC5B			1769	6.981	0.0554	No
18	RPL9			1788	6.888	0.0565	No
19	HYOU1			1806	6.782	0.0575	No
20	PDIA6			1980	6.116	0.0525	No
21	RPS14			2047	5.896	0.0514	No
22	NUCB2			2136	5.615	0.0495	No
23	RPS3			2200	5.404	0.0484	No
24	FAM120A			2445	4.736	0.0403	No
25	RPL23A			2661	4.286	0.0331	No
26	RPS24			2715	4.152	0.0321	No
27	DNAJB9			2733	4.122	0.0325	No
28	RPL23			2742	4.105	0.0332	No
29	EEF2			2774	4.032	0.0331	No
30	FTL			2919	3.762	0.0285	No
31	PDIA3			2945	3.710	0.0285	No
32	CDC5L			2965	3.669	0.0287	No
33	RPL34			2966	3.668	0.0296	No
34	TMED2			3029	3.568	0.0281	No
35	P4HB			3059	3.515	0.0279	No
36	AFTPH			3084	3.473	0.0278	No
37	HSP90B1			3151	3.351	0.0262	No
38	EPHB4			3507	2.853	0.0133	No
39	TRAM1			3681	2.671	0.0073	No
40	FICD			3705	2.632	0.0071	No
41	EIF5A			3712	2.624	0.0075	No
42	SGSM3			3719	2.613	0.0080	No
43	RPS27			3760	2.568	0.0071	No
44	PNRC1			3888	2.423	0.0028	No
45	RPS23			4068	2.247	-0.0035	No
46	RPL39			4087	2.231	-0.0036	No
47	RPL3			4096	2.226	-0.0033	No
48	EEF1A1			4648	1.739	-0.0240	No
49	RPS18			4759	1.649	-0.0278	No
50	PABPC1			4895	1.550	-0.0326	No
51	TMED7			4927	1.528	-0.0334	No
52	RPL5			4999	1.476	-0.0357	No
53	ST6GALNAC4			5203	1.352	-0.0432	No
54	RPL13A			5204	1.351	-0.0428	No
55	RPL37A			5298	1.297	-0.0460	No
56	RPS19			5342	1.269	-0.0474	No
57	RPS2			5348	1.266	-0.0472	No
58	RPS6			5456	1.206	-0.0510	No
59	RPL41			5567	1.139	-0.0550	No
60	HKDC1			5884	0.975	-0.0668	No
61	ARHGAP35			5969	0.942	-0.0698	No
62	SEL1L			6132	0.885	-0.0758	No
63	RPS7			6153	0.875	-0.0763	No
64	KLHL24			6453	0.777	-0.0876	No
65	RPL13			6459	0.775	-0.0876	No
66	MAN1A2			6485	0.767	-0.0883	No
67	RPS3A			6650	0.709	-0.0944	No
68	KLF5			6883	0.637	-0.1032	No
69	RPS11			7027	0.595	-0.1085	No
70	RARRES3			7145	0.565	-0.1128	No
71	ARIH1			7152	0.562	-0.1129	No
72	TXNRD1			7886	0.415	-0.1409	No
73	ARF4			8150	0.374	-0.1509	No
74	HUWE1			8212	0.366	-0.1531	No
75	NDRG1			8342	0.347	-0.1580	No
76	CANX			8348	0.345	-0.1581	No
77	LAMP3			8359	0.344	-0.1584	No
78	DNAJC10			8399	0.338	-0.1598	No
79	MTFR1			8479	0.324	-0.1627	No
80	SEL1L3			8595	0.310	-0.1671	No
81	MARCH5			8727	0.293	-0.1720	No
82	ACBD3			8774	0.287	-0.1737	No
83	UBC			8798	0.286	-0.1745	No
84	VASP			8943	0.267	-0.1799	No
85	RPLP0			9178	0.242	-0.1888	No
86	BTG1			9324	0.224	-0.1943	No
87	NQO1			9499	0.207	-0.2010	No
88	FAF2			9525	0.205	-0.2019	No
89	TPT1			9669	0.190	-0.2073	No
90	PRR15L			10040	0.159	-0.2214	No
91	UBXN4			10563	0.121	-0.2414	No
92	CREB1			10744	0.107	-0.2482	No
93	STX5			11016	0.091	-0.2586	No
94	RPL27A			11079	0.088	-0.2610	No
95	TBC1D15			11445	0.068	-0.2749	No
96	ELF3			11880	0.048	-0.2915	No
97	RAB2A			12297	0.031	-0.3075	No
98	GCNT3			12322	0.030	-0.3084	No
99	KAT6B			12427	0.025	-0.3123	No
100	SAT1			12782	0.011	-0.3259	No
101	MAP2K2			12922	0.007	-0.3312	No
102	DTX2P1-UPK3BP1-PMS2P11			12973	0.005	-0.3331	No
103	PJA2			12983	0.005	-0.3335	No
104	ARMCX3			13026	0.005	-0.3351	No
105	RPL12			13412	-0.009	-0.3498	No
106	S100P			13838	-0.025	-0.3661	No
107	CDC6			14100	-0.035	-0.3761	No
108	TMED5			14484	-0.051	-0.3907	No
109	PTPRF			14780	-0.061	-0.4020	No
110	NBR1			15081	-0.078	-0.4135	No
111	ZMYM4			15280	-0.089	-0.4211	No
112	LAMB3			15522	-0.104	-0.4303	No
113	ATF2			15697	-0.113	-0.4369	No
114	GLRX			15957	-0.131	-0.4468	No
115	AUH			16242	-0.151	-0.4576	No
116	RPL4			16586	-0.178	-0.4707	No
117	ESRP1			16926	-0.210	-0.4836	No
118	RPL10			17319	-0.251	-0.4986	No
119	SQSTM1			17662	-0.293	-0.5116	No
120	KDELR1			17905	-0.323	-0.5208	No
121	NUDT4			17928	-0.325	-0.5216	No
122	GFPT1			17970	-0.331	-0.5230	No
123	MCTP2			18206	-0.364	-0.5320	No
124	LRRFIP1			18317	-0.384	-0.5361	No
125	TMEM39A			18665	-0.448	-0.5493	No
126	MIA3			18750	-0.464	-0.5524	No
127	WDR45			18971	-0.509	-0.5606	No
128	ZNF236			19083	-0.530	-0.5648	No
129	AKR1C1			19331	-0.586	-0.5741	No
130	TANK			19607	-0.661	-0.5844	No
131	TSPAN31			20016	-0.787	-0.5999	No
132	ZNF282			20464	-0.947	-0.6168	No
133	FTH1			20690	-1.038	-0.6251	No
134	TMCO3			21044	-1.216	-0.6383	No
135	GCLM			21297	-1.363	-0.6476	No
136	HSPA13			21655	-1.583	-0.6609	No
137	NCOR1			21776	-1.668	-0.6651	No
138	TFG			21822	-1.705	-0.6664	No
139	THOC2			21860	-1.733	-0.6674	No
140	TCEA1			21870	-1.744	-0.6673	No
141	PDE8A			21931	-1.797	-0.6691	No
142	MTA1			22049	-1.903	-0.6731	No
143	PDCD4			22066	-1.916	-0.6732	No
144	BNIP3L			22352	-2.182	-0.6836	No
145	MBNL2			22372	-2.193	-0.6838	No
146	HOOK1			22715	-2.579	-0.6962	No
147	AKR1C2			22988	-2.925	-0.7059	No
148	FNDC3A			23128	-3.121	-0.7104	No
149	PRSS3			23213	-3.262	-0.7128	No
150	LPIN2			23237	-3.313	-0.7129	No
151	SERP1			23293	-3.403	-0.7141	No
152	GATAD1			23362	-3.537	-0.7158	No
153	ZNF277			23469	-3.733	-0.7190	No
154	HSPA9			23764	-4.390	-0.7291	No
155	CSNK1A1			23817	-4.510	-0.7300	No
156	NFIL3			24002	-5.017	-0.7358	No
157	GOT1			24030	-5.126	-0.7355	No
158	GOLGA5			24046	-5.172	-0.7348	No
159	ADNP2			24059	-5.207	-0.7339	No
160	SEC63			24263	-5.803	-0.7402	No
161	PPP1R15A			24307	-6.013	-0.7404	No
162	CLCN3			24325	-6.099	-0.7395	No
163	MTDH			24386	-6.334	-0.7402	No
164	ALDH3B1			24749	-7.958	-0.7520	No
165	RARA			24765	-8.044	-0.7506	No
166	COG5			24826	-8.358	-0.7508	No
167	SH3GLB1			24930	-9.123	-0.7524	No
168	CEP57			24978	-9.586	-0.7518	No
169	SLC3A2			25078	-10.370	-0.7530	No
170	RMND5B			25196	-11.549	-0.7546	No
171	RANBP9			25280	-12.443	-0.7546	No
172	PRNP			25527	-15.875	-0.7600	Yes
173	WIPI1			25583	-17.243	-0.7578	Yes
174	TTC3			25625	-18.237	-0.7548	Yes
175	LARP6			25627	-18.258	-0.7502	Yes
176	JAG1			25675	-19.325	-0.7471	Yes
177	EIF1			25731	-20.857	-0.7440	Yes
178	TFE3			25759	-21.664	-0.7395	Yes
179	UBE2H			25847	-25.130	-0.7365	Yes
180	CBX4			25927	-29.298	-0.7322	Yes
181	GRB10			25941	-30.158	-0.7251	Yes
182	TTC17			25965	-31.483	-0.7180	Yes
183	ARHGEF2			25969	-31.712	-0.7102	Yes
184	C6orf48			25975	-31.926	-0.7023	Yes
185	CD55			25987	-33.140	-0.6944	Yes
186	TES			26033	-37.078	-0.6868	Yes
187	SLC1A5			26086	-42.020	-0.6782	Yes
188	SLC7A1			26112	-45.465	-0.6677	Yes
189	WARS			26117	-46.483	-0.6561	Yes
190	AARS			26130	-48.060	-0.6444	Yes
191	SLC1A4			26133	-48.490	-0.6323	Yes
192	HERPUD1			26159	-53.015	-0.6199	Yes
193	PHLDA1			26170	-55.684	-0.6063	Yes
194	SARS			26192	-60.122	-0.5919	Yes
195	CEBPG			26210	-66.827	-0.5757	Yes
196	ASNS			26241	-83.978	-0.5557	Yes
197	CEBPB			26244	-86.643	-0.5340	Yes
198	GARS			26249	-89.806	-0.5115	Yes
199	VEGFA			26251	-89.987	-0.4888	Yes
200	MTHFD2			26257	-95.222	-0.4650	Yes
201	SLC43A1			26263	-98.209	-0.4405	Yes
202	ATF3			26295	-192.665	-0.3931	Yes
203	PCK2			26298	-198.705	-0.3431	Yes
204	IFRD1			26303	-230.785	-0.2851	Yes
205	TRIB3			26304	-235.323	-0.2258	Yes
206	DDIT4			26311	-299.207	-0.1506	Yes
207	INHBE			26312	-299.207	-0.0752	Yes
208	H1F0			26316	-299.207	0.0000	Yes

Fig 2: TIEN_INTESTINE_PROBIOTICS_24HR_DN: Random ES distribution   
Gene set null distribution of ES for TIEN_INTESTINE_PROBIOTICS_24HR_DN