Details for gene set FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS[GSEA]

Table: GSEA Results Summary

Dataset	NS50832_padj
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS
Enrichment Score (ES)	0.36791366
Normalized Enrichment Score (NES)	7.3137536
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CDKN1A			2	299.207	0.0034	Yes
2	TRIM22			9	242.455	0.0067	Yes
3	PHLDA3			12	209.243	0.0101	Yes
4	EDA2R			25	129.226	0.0131	Yes
5	SESN1			29	121.516	0.0165	Yes
6	RPS27L			40	106.999	0.0196	Yes
7	BAX			53	95.755	0.0226	Yes
8	BTG2			60	90.877	0.0258	Yes
9	POLH			68	81.789	0.0291	Yes
10	DDB2			70	81.275	0.0325	Yes
11	VWCE			71	80.787	0.0360	Yes
12	TUBB6			76	77.923	0.0393	Yes
13	SULF2			77	77.683	0.0428	Yes
14	ZMAT3			82	75.551	0.0461	Yes
15	TSPAN11			83	74.265	0.0496	Yes
16	TNFRSF10B			94	67.462	0.0527	Yes
17	AEN			98	66.791	0.0561	Yes
18	GRHL3			99	66.649	0.0596	Yes
19	FDXR			106	65.175	0.0628	Yes
20	TP53INP1			107	64.094	0.0663	Yes
21	BBC3			149	52.488	0.0682	Yes
22	MDM2			156	51.042	0.0715	Yes
23	TMEM64			185	43.060	0.0739	Yes
24	COBLL1			192	41.878	0.0771	Yes
25	XPC			204	40.284	0.0802	Yes
26	SLC12A4			218	38.278	0.0832	Yes
27	DRAM1			235	36.039	0.0860	Yes
28	TRIAP1			239	35.685	0.0894	Yes
29	RAP2B			246	35.107	0.0927	Yes
30	PCNA			255	34.423	0.0958	Yes
31	EI24			260	34.262	0.0992	Yes
32	RRM2B			281	31.368	0.1019	Yes
33	GDF15			292	30.340	0.1050	Yes
34	TNFRSF10D			306	29.057	0.1080	Yes
35	HEXIM1			324	27.700	0.1108	Yes
36	SPATA18			325	27.585	0.1143	Yes
37	TM7SF3			354	26.007	0.1167	Yes
38	IKBIP			371	25.423	0.1196	Yes
39	LMNA			381	24.893	0.1227	Yes
40	TNFRSF10C			390	24.454	0.1259	Yes
41	ZC3HAV1			393	24.314	0.1293	Yes
42	TNFRSF10A			412	23.568	0.1321	Yes
43	PLK2			461	21.783	0.1337	Yes
44	GPC1			503	20.492	0.1356	Yes
45	EPS8L2			524	19.973	0.1384	Yes
46	CDH8			537	19.545	0.1414	Yes
47	NTPCR			550	19.341	0.1444	Yes
48	PHPT1			551	19.325	0.1479	Yes
49	CYFIP2			556	19.234	0.1512	Yes
50	NYNRIN			598	18.362	0.1531	Yes
51	SFN			603	18.262	0.1565	Yes
52	RABGGTA			654	17.240	0.1580	Yes
53	DCP1B			659	17.150	0.1614	Yes
54	BRMS1L			673	16.884	0.1643	Yes
55	PLK3			703	16.241	0.1667	Yes
56	CLP1			705	16.207	0.1702	Yes
57	DDR1			711	16.106	0.1734	Yes
58	VCAN			712	16.078	0.1769	Yes
59	ASCC3			736	15.646	0.1795	Yes
60	RNF19B			823	14.447	0.1797	Yes
61	E2F7			830	14.296	0.1830	Yes
62	CCNG1			836	14.184	0.1863	Yes
63	RGMA			877	13.682	0.1882	Yes
64	CHST14			879	13.639	0.1916	Yes
65	SAC3D1			890	13.487	0.1947	Yes
66	DHRS3			933	12.896	0.1966	Yes
67	UTP3			959	12.561	0.1991	Yes
68	LIF			967	12.489	0.2024	Yes
69	ICOSLG			977	12.412	0.2055	Yes
70	DNAJB5			986	12.313	0.2087	Yes
71	MARCH8			996	12.210	0.2118	Yes
72	EPM2AIP1			1000	12.122	0.2152	Yes
73	RAD51C			1006	11.983	0.2185	Yes
74	EML2			1080	11.261	0.2192	Yes
75	RAB1A			1098	11.114	0.2220	Yes
76	GNAS			1126	10.933	0.2244	Yes
77	SLC4A11			1127	10.917	0.2279	Yes
78	NINJ1			1134	10.869	0.2312	Yes
79	TSKU			1145	10.780	0.2343	Yes
80	PANK1			1161	10.649	0.2372	Yes
81	FAM84B			1162	10.639	0.2407	Yes
82	FBXO22			1174	10.526	0.2437	Yes
83	MAP3K12			1175	10.523	0.2472	Yes
84	RGL1			1193	10.435	0.2500	Yes
85	ISYNA1			1242	9.978	0.2517	Yes
86	TGS1			1254	9.898	0.2547	Yes
87	PPM1D			1329	9.415	0.2554	Yes
88	FAS			1372	9.028	0.2573	Yes
89	ACER2			1407	8.821	0.2594	Yes
90	NHLH2			1473	8.436	0.2604	Yes
91	CCDC90B			1548	8.076	0.2611	Yes
92	PARD6G			1580	7.862	0.2634	Yes
93	ISCU			1592	7.774	0.2664	Yes
94	TRAF4			1685	7.356	0.2664	Yes
95	MGRN1			1739	7.123	0.2678	Yes
96	LRPAP1			1792	6.868	0.2693	Yes
97	DGKA			1870	6.514	0.2698	Yes
98	TMEM68			2014	5.998	0.2678	Yes
99	POLR2H			2080	5.778	0.2688	Yes
100	APAF1			2103	5.711	0.2714	Yes
101	HRAS			2126	5.642	0.2741	Yes
102	DYRK3			2142	5.596	0.2770	Yes
103	PTP4A1			2168	5.519	0.2795	Yes
104	SERPINB5			2201	5.403	0.2818	Yes
105	SCRIB			2207	5.381	0.2851	Yes
106	MICALL1			2215	5.357	0.2883	Yes
107	ETV7			2232	5.312	0.2912	Yes
108	FAM98C			2235	5.294	0.2946	Yes
109	ACTA2			2320	5.036	0.2948	Yes
110	PLXNB2			2377	4.904	0.2961	Yes
111	SERTAD1			2388	4.874	0.2992	Yes
112	PRKD2			2494	4.643	0.2987	Yes
113	ASTN2			2496	4.643	0.3021	Yes
114	FCHO2			2665	4.281	0.2992	Yes
115	TMEM63B			2753	4.074	0.2993	Yes
116	SOCS4			2790	3.997	0.3014	Yes
117	MLF2			2809	3.960	0.3042	Yes
118	TP53I3			2846	3.881	0.3063	Yes
119	F5			2917	3.765	0.3071	Yes
120	LNPEP			2986	3.643	0.3080	Yes
121	COL7A1			2997	3.632	0.3111	Yes
122	RETSAT			3069	3.503	0.3118	Yes
123	SRA1			3076	3.483	0.3151	Yes
124	ZNF385A			3164	3.340	0.3152	Yes
125	RRAD			3188	3.309	0.3178	Yes
126	IER5			3192	3.300	0.3212	Yes
127	SFXN5			3208	3.261	0.3241	Yes
128	TRIM35			3260	3.200	0.3256	Yes
129	TRIM32			3358	3.048	0.3254	Yes
130	TNFAIP8			3430	2.949	0.3262	Yes
131	NADSYN1			3448	2.934	0.3290	Yes
132	HSPA4L			3458	2.917	0.3321	Yes
133	EPHA2			3497	2.873	0.3341	Yes
134	WDR81			3562	2.787	0.3352	Yes
135	PRDM1			3563	2.787	0.3387	Yes
136	RCBTB1			3585	2.761	0.3413	Yes
137	WDR63			3590	2.757	0.3447	Yes
138	CROT			3637	2.718	0.3464	Yes
139	IGFBP7			3794	2.533	0.3439	Yes
140	ARFGEF2			3797	2.532	0.3473	Yes
141	GABARAPL2			3882	2.434	0.3475	Yes
142	ZNF219			4124	2.202	0.3418	Yes
143	AMZ2			4169	2.132	0.3436	Yes
144	MON2			4200	2.098	0.3459	Yes
145	POU3F1			4593	1.779	0.3343	Yes
146	EDN2			4622	1.762	0.3367	Yes
147	GSS			4711	1.683	0.3368	Yes
148	MRPL49			4721	1.676	0.3400	Yes
149	SYTL1			4760	1.649	0.3420	Yes
150	SMAD5			4783	1.633	0.3446	Yes
151	EFCAB10			4820	1.611	0.3467	Yes
152	SNX2			4899	1.546	0.3472	Yes
153	TANC1			4917	1.535	0.3501	Yes
154	USP15			5077	1.420	0.3474	Yes
155	POU2F2			5125	1.394	0.3491	Yes
156	CMBL			5156	1.377	0.3514	Yes
157	LCE1E			5194	1.357	0.3535	Yes
158	RPS19			5342	1.269	0.3513	Yes
159	NKAIN4			5370	1.250	0.3538	Yes
160	PML			5388	1.243	0.3566	Yes
161	GPX1			5395	1.241	0.3599	Yes
162	FBXW7			5460	1.204	0.3609	Yes
163	CD82			5515	1.169	0.3623	Yes
164	FLRT2			5580	1.131	0.3633	Yes
165	TLCD1			5767	1.036	0.3597	Yes
166	PARD6B			5812	1.009	0.3615	Yes
167	SMAD3			5839	0.995	0.3639	Yes
168	PRRG2			5984	0.937	0.3619	Yes
169	GBE1			6131	0.886	0.3598	Yes
170	AK3			6201	0.858	0.3606	Yes
171	SCN2A			6245	0.840	0.3624	Yes
172	TLR3			6260	0.836	0.3654	Yes
173	FAM198B			6286	0.827	0.3679	Yes
174	CEL			6587	0.731	0.3599	No
175	KRT15			6668	0.699	0.3603	No
176	RFK			6774	0.666	0.3597	No
177	EID2B			7082	0.580	0.3514	No
178	PBLD			7187	0.552	0.3509	No
179	CNOT6			7450	0.498	0.3443	No
180	FCHSD2			7457	0.496	0.3476	No
181	ZNF561			7650	0.454	0.3437	No
182	AKAP9			8470	0.326	0.3157	No
183	S100A2			8541	0.317	0.3165	No
184	NDUFV3			8750	0.292	0.3120	No
185	BLCAP			8902	0.270	0.3097	No
186	TRIP6			8988	0.263	0.3099	No
187	SLC25A45			9039	0.256	0.3115	No
188	ZNF79			9309	0.225	0.3046	No
189	SYNC			9314	0.225	0.3080	No
190	BTG1			9324	0.224	0.3111	No
191	AGBL5			9450	0.212	0.3098	No
192	PRKAB2			9465	0.210	0.3127	No
193	YAP1			9651	0.192	0.3091	No
194	C17orf82			10238	0.141	0.2901	No
195	CSNK1G1			10856	0.099	0.2699	No
196	SEMA3B			10871	0.099	0.2728	No
197	ITPKC			11305	0.076	0.2597	No
198	ABCA12			11410	0.069	0.2591	No
199	TMEM131			11691	0.056	0.2519	No
200	GADD45A			11891	0.047	0.2477	No
201	ALDH1A3			12164	0.036	0.2407	No
202	TRIB1			12362	0.028	0.2367	No
203	BCL9L			12424	0.026	0.2378	No
204	PADI4			12429	0.025	0.2411	No
205	ZNF337			12497	0.022	0.2420	No
206	BLOC1S2			12926	0.006	0.2291	No
207	C12orf45			13793	-0.024	0.1993	No
208	DUSP14			14069	-0.035	0.1922	No
209	RALGAPB			14259	-0.043	0.1884	No
210	HHAT			14320	-0.045	0.1896	No
211	ANXA4			14971	-0.071	0.1681	No
212	EFNB1			15532	-0.104	0.1501	No
213	KCTD1			15800	-0.120	0.1433	No
214	PDE4C			16362	-0.158	0.1253	No
215	ZNF564			16449	-0.166	0.1254	No
216	ANKRA2			16458	-0.167	0.1286	No
217	MBD5			16562	-0.175	0.1282	No
218	ARAP1			16612	-0.181	0.1298	No
219	KLHL12			18419	-0.403	0.0639	No
220	ZNF37A			18561	-0.426	0.0619	No
221	KIAA1217			18638	-0.441	0.0625	No
222	BCL10			18811	-0.474	0.0594	No
223	LRP1			18940	-0.503	0.0579	No
224	ZNF423			19207	-0.557	0.0512	No
225	ABCB6			19428	-0.613	0.0462	No
226	PSTPIP2			19645	-0.674	0.0414	No
227	OBSL1			19670	-0.680	0.0440	No
228	MCC			19736	-0.694	0.0450	No
229	STAT3			20290	-0.880	0.0272	No
230	TEAD3			20321	-0.891	0.0295	No
231	CSF1			20430	-0.932	0.0289	No
232	STX6			20551	-0.981	0.0278	No
233	MFAP3L			20566	-0.987	0.0307	No
234	ARHGAP42			20840	-1.114	0.0237	No
235	PPP1R3C			20907	-1.143	0.0246	No
236	NCEH1			21123	-1.260	0.0199	No
237	HIST2H2BE			21206	-1.312	0.0202	No
238	PTEN			21288	-1.359	0.0206	No
239	PPFIBP1			21445	-1.449	0.0181	No
240	ORAI3			21635	-1.567	0.0143	No
241	APOBEC3C			21718	-1.633	0.0146	No
242	PRKAB1			21750	-1.651	0.0169	No
243	REV3L			21780	-1.669	0.0193	No
244	BCL2L1			21802	-1.687	0.0220	No
245	ITGA3			22089	-1.937	0.0145	No
246	TET2			22334	-2.161	0.0086	No
247	SUPT7L			22342	-2.171	0.0118	No
248	LPXN			22548	-2.375	0.0074	No
249	KCNN4			22561	-2.396	0.0104	No
250	GNAI1			23408	-3.628	-0.0186	No
251	BTBD10			23438	-3.679	-0.0162	No
252	HES1			23488	-3.766	-0.0146	No
253	MAST4			23769	-4.402	-0.0219	No
254	TRUB1			23889	-4.708	-0.0230	No
255	GREB1			23915	-4.774	-0.0205	No
256	BHLHE40			24138	-5.407	-0.0255	No
257	CFLAR			24227	-5.676	-0.0254	No
258	CDC42SE1			24321	-6.075	-0.0255	No
259	SERPINE1			24389	-6.348	-0.0246	No
260	CPEB2			24429	-6.500	-0.0226	No
261	SLC46A1			24482	-6.662	-0.0211	No
262	BBS2			24529	-6.878	-0.0194	No
263	CPSF4			24665	-7.513	-0.0211	No
264	SLC9A1			24734	-7.850	-0.0202	No
265	GCH1			24774	-8.103	-0.0182	No
266	MFGE8			24873	-8.686	-0.0185	No
267	IER3			24909	-8.968	-0.0164	No
268	NUPR1			24923	-9.037	-0.0134	No
269	RNF144B			24962	-9.378	-0.0114	No
270	KRT8			25119	-10.758	-0.0139	No
271	KLHDC7A			25193	-11.514	-0.0132	No
272	MRPL39			25226	-11.847	-0.0109	No
273	TP53			25300	-12.686	-0.0102	No
274	BCL6			25317	-12.864	-0.0074	No
275	RIN1			25419	-14.202	-0.0078	No
276	IRF2BPL			25985	-33.000	-0.0260	No
277	FBN2			26004	-34.322	-0.0232	No
278	IGDCC4			26042	-38.110	-0.0211	No
279	PMAIP1			26053	-38.997	-0.0180	No
280	LIMA1			26094	-42.892	-0.0161	No
281	NEFL			26149	-51.235	-0.0147	No
282	SARS			26192	-60.122	-0.0128	No
283	SLC30A1			26223	-73.941	-0.0105	No
284	RGS16			26231	-76.235	-0.0073	No
285	SESN2			26273	-109.055	-0.0054	No
286	TXNIP			26293	-180.286	-0.0026	No
287	ATF3			26295	-192.665	0.0008	No

Fig 2: FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS: Random ES distribution   
Gene set null distribution of ES for FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS