Details for gene set REACTOME_METABOLISM_OF_RNA[GSEA]

Table: GSEA Results Summary

Dataset	NS50832_padj
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	REACTOME_METABOLISM_OF_RNA
Enrichment Score (ES)	0.36872008
Normalized Enrichment Score (NES)	7.1114483
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: REACTOME_METABOLISM_OF_RNA   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	HSPA8			56	93.481	0.0015	Yes
2	HSPA1B			67	84.429	0.0048	Yes
3	RPS4Y1			96	67.281	0.0074	Yes
4	EIF4A2			197	41.168	0.0073	Yes
5	PRKCA			252	34.592	0.0089	Yes
6	GEMIN4			272	32.385	0.0118	Yes
7	MAPK11			404	23.800	0.0105	Yes
8	LSM3			500	20.523	0.0105	Yes
9	WDR77			510	20.322	0.0138	Yes
10	RPS26			579	18.677	0.0149	Yes
11	EIF4G1			621	17.869	0.0170	Yes
12	PSME4			628	17.753	0.0204	Yes
13	DCP1B			659	17.150	0.0230	Yes
14	NUP62			793	14.911	0.0215	Yes
15	NUP37			795	14.910	0.0252	Yes
16	SEH1L			800	14.882	0.0287	Yes
17	RPS15			965	12.532	0.0261	Yes
18	PSMD1			1070	11.432	0.0257	Yes
19	SNRPG			1076	11.321	0.0292	Yes
20	PPP2R1A			1078	11.290	0.0329	Yes
21	EXOSC9			1136	10.848	0.0344	Yes
22	TGS1			1254	9.898	0.0335	Yes
23	POM121			1387	8.936	0.0322	Yes
24	PSMD12			1439	8.659	0.0339	Yes
25	RPL7A			1466	8.492	0.0365	Yes
26	EIF4B			1567	7.940	0.0364	Yes
27	SNRPD3			1578	7.869	0.0397	Yes
28	AAAS			1707	7.222	0.0384	Yes
29	PSMD11			1710	7.211	0.0420	Yes
30	SNRPD2			1742	7.092	0.0445	Yes
31	PSMF1			1785	6.897	0.0466	Yes
32	RPL9			1788	6.888	0.0502	Yes
33	PSMA4			1791	6.873	0.0538	Yes
34	PRKCD			1834	6.713	0.0559	Yes
35	SNRPE			1908	6.371	0.0567	Yes
36	HNRNPD			1950	6.218	0.0588	Yes
37	PATL1			1952	6.209	0.0625	Yes
38	SMG8			1964	6.176	0.0657	Yes
39	RPS14			2047	5.896	0.0662	Yes
40	RPL35A			2053	5.885	0.0697	Yes
41	SNRPF			2066	5.846	0.0729	Yes
42	PSME1			2182	5.448	0.0722	Yes
43	RPL24			2192	5.431	0.0755	Yes
44	RPS3			2200	5.404	0.0789	Yes
45	RPL11			2344	5.001	0.0771	Yes
46	RPL38			2472	4.679	0.0759	Yes
47	PSMD6			2506	4.625	0.0783	Yes
48	NUP153			2581	4.462	0.0792	Yes
49	SNRPD1			2610	4.392	0.0818	Yes
50	EIF4A3			2614	4.386	0.0853	Yes
51	PSMA2			2640	4.325	0.0881	Yes
52	RPL23A			2661	4.286	0.0910	Yes
53	PSMB2			2666	4.280	0.0945	Yes
54	EIF4E			2687	4.223	0.0974	Yes
55	RPS24			2715	4.152	0.1000	Yes
56	RPL23			2742	4.105	0.1027	Yes
57	GEMIN6			2760	4.053	0.1057	Yes
58	RPL28			2804	3.969	0.1078	Yes
59	PPP2R2A			2811	3.948	0.1112	Yes
60	PSMD10			2889	3.802	0.1119	Yes
61	RPL29			2937	3.726	0.1138	Yes
62	RPL6			2962	3.681	0.1166	Yes
63	RPL34			2966	3.668	0.1201	Yes
64	NCBP2			3014	3.587	0.1220	Yes
65	NUP35			3082	3.476	0.1231	Yes
66	NUP188			3106	3.445	0.1259	Yes
67	EXOSC2			3127	3.389	0.1288	Yes
68	CASC3			3132	3.375	0.1323	Yes
69	PSMA3			3248	3.209	0.1316	Yes
70	LSM6			3296	3.144	0.1335	Yes
71	RPL27			3363	3.039	0.1346	Yes
72	RPL7			3370	3.031	0.1380	Yes
73	PSMD14			3434	2.947	0.1393	Yes
74	XPO1			3456	2.917	0.1422	Yes
75	EXOSC6			3457	2.917	0.1458	Yes
76	PSMB3			3510	2.848	0.1475	Yes
77	PSMD13			3598	2.753	0.1479	Yes
78	UBA52			3612	2.746	0.1510	Yes
79	PSMD9			3627	2.733	0.1542	Yes
80	RPL26			3628	2.732	0.1579	Yes
81	PSMA5			3694	2.650	0.1590	Yes
82	PSMB4			3707	2.631	0.1623	Yes
83	RPL35			3726	2.603	0.1652	Yes
84	RPS27			3760	2.568	0.1677	Yes
85	DDX6			3934	2.383	0.1647	Yes
86	PSMB7			3958	2.358	0.1675	Yes
87	MAGOH			4005	2.314	0.1694	Yes
88	CNOT8			4010	2.306	0.1729	Yes
89	RPS23			4068	2.247	0.1744	Yes
90	RPL39			4087	2.231	0.1774	Yes
91	RPL31			4095	2.227	0.1808	Yes
92	RPL3			4096	2.226	0.1845	Yes
93	NUP85			4114	2.210	0.1875	Yes
94	PSMD2			4164	2.139	0.1893	Yes
95	PSMD5			4165	2.139	0.1930	Yes
96	RPS16			4171	2.131	0.1964	Yes
97	PSME2			4323	1.995	0.1943	Yes
98	SNRPB			4336	1.985	0.1975	Yes
99	EXOSC3			4340	1.983	0.2011	Yes
100	PSMD3			4351	1.970	0.2044	Yes
101	PSMC4			4425	1.910	0.2053	Yes
102	SMG5			4501	1.848	0.2061	Yes
103	YWHAB			4514	1.842	0.2093	Yes
104	RPLP1			4555	1.806	0.2114	Yes
105	PSMA6			4609	1.769	0.2131	Yes
106	ELAVL1			4649	1.739	0.2152	Yes
107	RPL36			4672	1.720	0.2181	Yes
108	RPS17			4718	1.678	0.2200	Yes
109	RPS18			4759	1.649	0.2222	Yes
110	GEMIN5			4873	1.567	0.2215	Yes
111	SMG6			4889	1.554	0.2246	Yes
112	PABPC1			4895	1.550	0.2281	Yes
113	NUP214			4939	1.518	0.2301	Yes
114	PSMB5			4944	1.512	0.2336	Yes
115	LSM1			4986	1.483	0.2357	Yes
116	RPL5			4999	1.476	0.2390	Yes
117	RPL26L1			5047	1.441	0.2408	Yes
118	RANBP2			5091	1.412	0.2429	Yes
119	RPL13A			5204	1.351	0.2422	Yes
120	PRMT5			5247	1.327	0.2443	Yes
121	PSMC5			5249	1.327	0.2479	Yes
122	PSMB6			5289	1.303	0.2501	Yes
123	RPL18			5293	1.299	0.2537	Yes
124	RPL37A			5298	1.297	0.2572	Yes
125	RPL37			5305	1.290	0.2606	Yes
126	RPS19			5342	1.269	0.2629	Yes
127	RPS2			5348	1.266	0.2664	Yes
128	NUP50			5435	1.218	0.2668	Yes
129	LSM2			5438	1.216	0.2704	Yes
130	RPS6			5456	1.206	0.2734	Yes
131	RPS29			5477	1.189	0.2763	Yes
132	SMG7			5479	1.189	0.2800	Yes
133	PSMD8			5541	1.152	0.2813	Yes
134	PSMC1			5559	1.143	0.2843	Yes
135	RPL41			5567	1.139	0.2877	Yes
136	FAU			5616	1.115	0.2896	Yes
137	RPL10A			5633	1.101	0.2926	Yes
138	PSMB1			5677	1.079	0.2947	Yes
139	EXOSC7			5726	1.053	0.2965	Yes
140	NCBP1			5753	1.042	0.2992	Yes
141	MAPK14			5854	0.987	0.2990	Yes
142	PHAX			5931	0.958	0.2998	Yes
143	LSM4			5982	0.937	0.3015	Yes
144	PSMD4			6022	0.922	0.3037	Yes
145	RPL32			6148	0.878	0.3026	Yes
146	RPS7			6153	0.875	0.3061	Yes
147	RPS15A			6219	0.850	0.3073	Yes
148	MAPKAPK2			6284	0.828	0.3085	Yes
149	YWHAZ			6285	0.828	0.3122	Yes
150	RPL5P1			6300	0.824	0.3153	Yes
151	KHSRP			6364	0.803	0.3166	Yes
152	RPL15			6409	0.790	0.3186	Yes
153	DIS3			6454	0.777	0.3205	Yes
154	RPL13			6459	0.775	0.3241	Yes
155	PSMC3			6511	0.758	0.3258	Yes
156	RPS3A			6650	0.709	0.3242	Yes
157	RPL36A			6658	0.705	0.3276	Yes
158	RPL17			6659	0.705	0.3312	Yes
159	RPS10			6702	0.688	0.3333	Yes
160	RPS25			6731	0.675	0.3359	Yes
161	RPL23AP2			6738	0.673	0.3394	Yes
162	RPS5			6771	0.666	0.3418	Yes
163	RPL21			6814	0.654	0.3439	Yes
164	DDX20			6887	0.635	0.3448	Yes
165	RPS11			7027	0.595	0.3431	Yes
166	PSMD7			7143	0.565	0.3424	Yes
167	RPL19			7199	0.549	0.3439	Yes
168	RPL18A			7272	0.534	0.3449	Yes
169	CNOT6			7450	0.498	0.3417	Yes
170	UPF3A			7468	0.492	0.3448	Yes
171	RPS29P3			7508	0.484	0.3469	Yes
172	TPR			7525	0.481	0.3500	Yes
173	RPS13			7632	0.457	0.3496	Yes
174	PSMC2			7670	0.452	0.3519	Yes
175	RPS28P7			7787	0.429	0.3511	Yes
176	RPS9			7944	0.405	0.3488	Yes
177	RPS27A			7967	0.401	0.3516	Yes
178	EDC3			8029	0.392	0.3529	Yes
179	RPS28			8172	0.371	0.3512	Yes
180	SNUPN			8247	0.361	0.3520	Yes
181	RPL8			8309	0.354	0.3533	Yes
182	RPL34P27			8379	0.341	0.3544	Yes
183	EIF4A1			8417	0.335	0.3566	Yes
184	RPL22			8565	0.314	0.3547	Yes
185	RPS20			8582	0.312	0.3577	Yes
186	NUP93			8606	0.308	0.3605	Yes
187	GSPT2			8627	0.306	0.3634	Yes
188	RAE1			8729	0.293	0.3632	Yes
189	RPS15P5			8820	0.282	0.3634	Yes
190	LSM5			8837	0.280	0.3665	Yes
191	RPL7AP66			8928	0.269	0.3667	Yes
192	RPSA			9117	0.248	0.3632	Yes
193	PSMB10			9152	0.244	0.3656	Yes
194	RPLP0			9178	0.242	0.3683	Yes
195	NUP133			9263	0.231	0.3687	Yes
196	HSPB1			9513	0.206	0.3628	No
197	RPS4X			9559	0.203	0.3648	No
198	PSMC6			9732	0.184	0.3619	No
199	RNPS1			9851	0.174	0.3610	No
200	RPL21P75			9914	0.169	0.3623	No
201	RPS27AP11			10159	0.148	0.3566	No
202	PSMA7			10198	0.144	0.3588	No
203	EXOSC4			10233	0.142	0.3612	No
204	RPL17P36			10740	0.107	0.3454	No
205	RPSAP12			10985	0.093	0.3398	No
206	RPL27A			11079	0.088	0.3399	No
207	ZFP36L1			11150	0.084	0.3408	No
208	RPSAP9			11187	0.083	0.3431	No
209	TNKS1BP1			11231	0.081	0.3452	No
210	RPS8			11532	0.063	0.3373	No
211	RPL26P30			11586	0.061	0.3390	No
212	RPL23AP18			11744	0.053	0.3366	No
213	RPS21			12030	0.043	0.3294	No
214	RPLP2			12073	0.041	0.3314	No
215	RPL10P9			12259	0.033	0.3280	No
216	CNOT2			12436	0.025	0.3249	No
217	SMN1			12775	0.011	0.3156	No
218	UPF2			13127	-0.000	0.3058	No
219	RPL12			13412	-0.009	0.2986	No
220	RPS12			13422	-0.009	0.3019	No
221	NUP88			13520	-0.013	0.3019	No
222	RPL30			13761	-0.023	0.2963	No
223	RPL21P16			14031	-0.033	0.2897	No
224	RPS19P3			14316	-0.045	0.2824	No
225	SMG1			14630	-0.055	0.2741	No
226	NUP107			14717	-0.058	0.2745	No
227	RPL3L			14818	-0.062	0.2743	No
228	PPP2CA			15069	-0.077	0.2684	No
229	RPS15AP11			15181	-0.083	0.2678	No
230	NUP155			15252	-0.087	0.2688	No
231	PSMB9			15381	-0.096	0.2676	No
232	PSMA1			15404	-0.097	0.2704	No
233	TNPO1			15597	-0.108	0.2667	No
234	ZFP36			16071	-0.139	0.2522	No
235	RPL14			16208	-0.148	0.2507	No
236	RPL10P16			16241	-0.150	0.2531	No
237	RPL23AP42			16447	-0.166	0.2489	No
238	RPL4			16586	-0.178	0.2473	No
239	EDC4			16873	-0.205	0.2400	No
240	RPL10			17319	-0.251	0.2266	No
241	SNRPD2P1			17403	-0.264	0.2271	No
242	RBM8A			17446	-0.269	0.2291	No
243	DCP2			17469	-0.271	0.2320	No
244	DCPS			17675	-0.295	0.2278	No
245	CNOT3			18104	-0.349	0.2150	No
246	NUP43			18394	-0.397	0.2076	No
247	CNOT4			18759	-0.466	0.1973	No
248	AKT1			19355	-0.593	0.1781	No
249	PSMB8			19804	-0.717	0.1646	No
250	NUP54			19910	-0.754	0.1643	No
251	TNFSF13			20266	-0.874	0.1543	No
252	NUPL2			20284	-0.879	0.1573	No
253	CNOT10			20323	-0.892	0.1595	No
254	UPF3B			20527	-0.972	0.1554	No
255	FAM153A			20542	-0.977	0.1586	No
256	CNOT7			20626	-1.009	0.1591	No
257	GEMIN2			21212	-1.316	0.1403	No
258	ANP32A			21219	-1.318	0.1437	No
259	NUP205			22101	-1.943	0.1136	No
260	ETF1			22379	-2.197	0.1066	No
261	GEMIN7			22475	-2.310	0.1066	No
262	EXOSC1			22525	-2.354	0.1084	No
263	CLNS1A			22699	-2.568	0.1055	No
264	EXOSC5			23388	-3.601	0.0827	No
265	SMG9			23473	-3.740	0.0832	No
266	XRN1			23652	-4.122	0.0800	No
267	PAIP1			24320	-6.073	0.0581	No
268	EXOSC8			24629	-7.353	0.0499	No
269	DCP1A			24790	-8.188	0.0475	No
270	SMN2			24938	-9.174	0.0455	No
271	PARN			25082	-10.411	0.0437	No
272	NUP210			25609	-17.999	0.0272	No

Fig 2: REACTOME_METABOLISM_OF_RNA: Random ES distribution   
Gene set null distribution of ES for REACTOME_METABOLISM_OF_RNA