Details for gene set VECCHI_GASTRIC_CANCER_EARLY_DN[GSEA]

Table: GSEA Results Summary

Dataset	NS50832_padj
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	VECCHI_GASTRIC_CANCER_EARLY_DN
Enrichment Score (ES)	-0.2122346
Normalized Enrichment Score (NES)	-4.108077
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: VECCHI_GASTRIC_CANCER_EARLY_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PLP1			31	117.747	0.0025	No
2	GLUL			84	72.529	0.0041	No
3	CITED2			143	54.021	0.0055	No
4	PCDH7			146	52.996	0.0091	No
5	IRX2			176	44.698	0.0116	No
6	C14orf132			195	41.676	0.0146	No
7	FHL1			544	19.472	0.0049	No
8	WIF1			644	17.424	0.0047	No
9	INA			875	13.684	-0.0004	No
10	HHIP			1129	10.894	-0.0065	No
11	UNC5D			1318	9.490	-0.0101	No
12	PRIMA1			1362	9.132	-0.0081	No
13	SOX2			1391	8.931	-0.0055	No
14	SYNM			1396	8.885	-0.0020	No
15	TTLL7			1401	8.863	0.0015	No
16	BEX2			1464	8.495	0.0028	No
17	CHGB			1472	8.437	0.0061	No
18	TMEM47			1564	7.957	0.0063	No
19	MAGEH1			1585	7.816	0.0092	No
20	YIF1B			1622	7.635	0.0114	No
21	SEMA4A			1641	7.532	0.0144	No
22	ARMCX2			1849	6.638	0.0101	No
23	IRX3			1911	6.352	0.0114	No
24	EFEMP1			1926	6.296	0.0145	No
25	FAM46C			2099	5.720	0.0116	No
26	VEPH1			2143	5.596	0.0136	No
27	LRRC17			2205	5.393	0.0149	No
28	ENPP2			2284	5.147	0.0155	No
29	CNN1			2347	4.991	0.0168	No
30	MAF			2406	4.831	0.0182	No
31	CLDND1			2469	4.682	0.0195	No
32	SRPX			2743	4.103	0.0127	No
33	SSTR1			2810	3.957	0.0138	No
34	AQP4			3001	3.616	0.0101	No
35	GPX3			3011	3.596	0.0134	No
36	SLC2A12			3012	3.591	0.0171	No
37	CLU			3249	3.207	0.0117	No
38	DTNA			3295	3.148	0.0136	No
39	NTN4			3301	3.137	0.0170	No
40	SVEP1			3302	3.134	0.0207	No
41	DNER			3305	3.131	0.0243	No
42	NR3C2			3899	2.409	0.0052	No
43	PCDH9			3903	2.405	0.0087	No
44	RGS4			4025	2.299	0.0077	No
45	SST			4210	2.093	0.0043	No
46	BEX5			4226	2.079	0.0073	No
47	RAI2			4306	2.011	0.0080	No
48	MANEA			4370	1.958	0.0092	No
49	LDHB			4389	1.937	0.0122	No
50	SIDT2			4896	1.549	-0.0036	No
51	SLC36A4			4909	1.539	-0.0004	No
52	PPP2R3A			5017	1.464	-0.0009	No
53	LIFR			5046	1.441	0.0017	No
54	KIAA1324			5368	1.250	-0.0070	No
55	PDGFC			5424	1.228	-0.0055	No
56	GRIP2			5543	1.151	-0.0063	No
57	VSTM2A			5566	1.140	-0.0035	No
58	TMEFF2			5631	1.104	-0.0023	No
59	ST8SIA4			5769	1.034	-0.0040	No
60	FCRL5			5974	0.940	-0.0081	No
61	ENTPD3			6150	0.877	-0.0112	No
62	TMPRSS6			6348	0.807	-0.0151	No
63	RNLS			6427	0.786	-0.0145	No
64	ACOX2			6529	0.753	-0.0147	No
65	PLIN1			6544	0.750	-0.0116	No
66	PGC			6615	0.720	-0.0106	No
67	SFRP1			6633	0.715	-0.0076	No
68	TCEAL2			6687	0.691	-0.0060	No
69	ID4			6813	0.655	-0.0072	No
70	USP51			6818	0.653	-0.0037	No
71	GADD45B			7123	0.569	-0.0117	No
72	PBLD			7187	0.552	-0.0105	No
73	ATP4A			7308	0.528	-0.0114	No
74	BEND5			7341	0.519	-0.0090	No
75	GNG7			7356	0.517	-0.0059	No
76	TMED6			7438	0.500	-0.0053	No
77	SOBP			7549	0.475	-0.0059	No
78	CYBRD1			7823	0.424	-0.0127	No
79	MCTP1			7915	0.410	-0.0126	No
80	UBL3			8185	0.369	-0.0193	No
81	SCARA5			8199	0.368	-0.0161	No
82	NLRP7			8243	0.362	-0.0141	No
83	APOA1			8324	0.352	-0.0135	No
84	KIF5C			8327	0.351	-0.0100	No
85	BNIP3			8337	0.349	-0.0067	No
86	GMPR			8477	0.324	-0.0084	No
87	GATA5			8526	0.318	-0.0065	No
88	GSPT2			8627	0.306	-0.0067	No
89	ACE2			8733	0.293	-0.0071	No
90	SLC16A7			8846	0.279	-0.0078	No
91	MTTP			8870	0.275	-0.0050	No
92	SLC28A2			8951	0.266	-0.0044	No
93	ADRB2			9079	0.251	-0.0057	No
94	METTL7A			9196	0.240	-0.0065	No
95	ABAT			9210	0.238	-0.0033	No
96	NME5			9428	0.214	-0.0080	No
97	HLA-DOB			9701	0.186	-0.0148	No
98	PRKACB			9831	0.176	-0.0161	No
99	SMARCA1			9993	0.163	-0.0186	No
100	TPCN2			10142	0.149	-0.0207	No
101	DNAJC6			10177	0.146	-0.0183	No
102	CYP2C18			10892	0.098	-0.0421	No
103	CYP3A4			10973	0.094	-0.0415	No
104	LYVE1			11148	0.084	-0.0445	No
105	LONRF2			11804	0.051	-0.0660	No
106	KCNJ15			11867	0.048	-0.0648	No
107	BEX1			12077	0.041	-0.0691	No
108	MAMDC2			12250	0.033	-0.0721	No
109	RBPMS2			12285	0.032	-0.0697	No
110	MYRIP			12562	0.020	-0.0767	No
111	MFAP5			12936	0.006	-0.0874	No
112	ARHGAP24			13093	0.001	-0.0897	No
113	ENTPD5			13316	-0.006	-0.0946	No
114	IDUA			13424	-0.009	-0.0950	No
115	FKBP5			13452	-0.010	-0.0924	No
116	CKMT2			13563	-0.015	-0.0930	No
117	RNF180			13660	-0.018	-0.0930	No
118	PDK4			13791	-0.024	-0.0944	No
119	MAP9			14381	-0.047	-0.1133	No
120	SLC26A7			14536	-0.052	-0.1156	No
121	AFF3			14572	-0.053	-0.1133	No
122	CD302			14800	-0.062	-0.1184	No
123	CD79A			14923	-0.068	-0.1194	No
124	CKAP2			14956	-0.070	-0.1170	No
125	TMEM100			15021	-0.074	-0.1158	No
126	KCNE2			15054	-0.076	-0.1134	No
127	MT1M			15243	-0.087	-0.1169	No
128	NAP1L2			15347	-0.094	-0.1172	No
129	ADAM28			15574	-0.107	-0.1223	No
130	ST3GAL6			15813	-0.121	-0.1278	No
131	MAL			16028	-0.136	-0.1323	No
132	ALDH1A2			16212	-0.148	-0.1357	No
133	HPGD			16300	-0.154	-0.1354	No
134	PLLP			16518	-0.172	-0.1401	No
135	CPA2			16742	-0.193	-0.1450	No
136	ARMCX1			16771	-0.196	-0.1424	No
137	SPINK2			17353	-0.257	-0.1611	No
138	RBP2			17512	-0.276	-0.1635	No
139	GPR155			17536	-0.279	-0.1607	No
140	SOSTDC1			17672	-0.294	-0.1623	No
141	LEPR			17902	-0.323	-0.1674	No
142	MYOT			18137	-0.353	-0.1727	No
143	SOX6			18167	-0.358	-0.1702	No
144	AGTR1			18281	-0.377	-0.1709	No
145	FUT9			18366	-0.393	-0.1705	No
146	GC			18676	-0.449	-0.1787	No
147	BMPR1B			18895	-0.493	-0.1834	No
148	HLF			19420	-0.612	-0.1999	No
149	PPOX			19743	-0.697	-0.2086	Yes
150	REG1A			19744	-0.698	-0.2049	Yes
151	GABRB3			19774	-0.707	-0.2024	Yes
152	ANGPTL1			19818	-0.725	-0.2004	Yes
153	GCNT2			19933	-0.760	-0.2011	Yes
154	EBF1			19965	-0.771	-0.1987	Yes
155	DAB1			19977	-0.775	-0.1954	Yes
156	CCPG1			19990	-0.782	-0.1923	Yes
157	SNRPN			20021	-0.789	-0.1898	Yes
158	SCUBE2			20091	-0.806	-0.1888	Yes
159	CFL2			20208	-0.852	-0.1896	Yes
160	ASPA			20250	-0.866	-0.1875	Yes
161	GIP			20279	-0.878	-0.1849	Yes
162	PLCXD3			20413	-0.928	-0.1864	Yes
163	GREM2			20479	-0.953	-0.1852	Yes
164	KCNMB2			20530	-0.973	-0.1835	Yes
165	PTGER3			20721	-1.056	-0.1871	Yes
166	SORBS2			20831	-1.108	-0.1877	Yes
167	SYNPO2			20858	-1.121	-0.1850	Yes
168	MAGI2			20938	-1.159	-0.1844	Yes
169	FIGN			21064	-1.230	-0.1855	Yes
170	LAMA2			21082	-1.242	-0.1825	Yes
171	PELI2			21101	-1.249	-0.1796	Yes
172	RAB27A			21149	-1.274	-0.1777	Yes
173	KIT			21165	-1.287	-0.1747	Yes
174	GNAO1			21169	-1.289	-0.1711	Yes
175	WIPF3			21305	-1.365	-0.1727	Yes
176	ANGPT1			21314	-1.369	-0.1693	Yes
177	KANK4			21320	-1.372	-0.1659	Yes
178	ZNF385B			21363	-1.400	-0.1638	Yes
179	JAM2			21427	-1.439	-0.1626	Yes
180	TMEM27			21440	-1.446	-0.1594	Yes
181	C2orf40			21533	-1.505	-0.1593	Yes
182	ALDH6A1			21603	-1.547	-0.1583	Yes
183	THSD4			21616	-1.554	-0.1551	Yes
184	SLC18A2			21624	-1.560	-0.1517	Yes
185	SNX24			21648	-1.576	-0.1490	Yes
186	CYTIP			21723	-1.636	-0.1482	Yes
187	PTPRZ1			21730	-1.642	-0.1447	Yes
188	GAS1			21755	-1.655	-0.1420	Yes
189	ASAH2B			21766	-1.659	-0.1387	Yes
190	PRKD3			21969	-1.838	-0.1428	Yes
191	ESRRG			22069	-1.918	-0.1430	Yes
192	RBMS3			22109	-1.951	-0.1408	Yes
193	CGNL1			22208	-2.038	-0.1410	Yes
194	PRDM16			22321	-2.152	-0.1416	Yes
195	UBE2J1			22476	-2.310	-0.1439	Yes
196	GHR			22496	-2.324	-0.1410	Yes
197	RAB9B			22500	-2.328	-0.1374	Yes
198	FAM3B			22579	-2.419	-0.1368	Yes
199	GPR27			22740	-2.608	-0.1393	Yes
200	RCAN2			22804	-2.692	-0.1380	Yes
201	SCN7A			22862	-2.788	-0.1366	Yes
202	KLF15			22876	-2.802	-0.1334	Yes
203	C7			22906	-2.827	-0.1309	Yes
204	AKR1C2			22988	-2.925	-0.1303	Yes
205	MZB1			23000	-2.943	-0.1271	Yes
206	ADA			23091	-3.070	-0.1269	Yes
207	RASSF10			23144	-3.145	-0.1253	Yes
208	RGMB			23260	-3.343	-0.1260	Yes
209	MT1H			23299	-3.419	-0.1238	Yes
210	NLRX1			23326	-3.465	-0.1212	Yes
211	SLC15A1			23389	-3.602	-0.1199	Yes
212	SETBP1			23585	-3.977	-0.1238	Yes
213	SLC1A2			23754	-4.357	-0.1266	Yes
214	SH3GL2			23763	-4.389	-0.1232	Yes
215	PDGFD			23772	-4.405	-0.1199	Yes
216	ALDH1A1			23818	-4.510	-0.1180	Yes
217	RPS6KA6			23855	-4.592	-0.1157	Yes
218	CHRDL1			23901	-4.737	-0.1138	Yes
219	SYT4			24069	-5.238	-0.1165	Yes
220	IL6R			24075	-5.248	-0.1131	Yes
221	ITIH5			24085	-5.267	-0.1098	Yes
222	DTNB			24149	-5.434	-0.1085	Yes
223	PKIB			24187	-5.562	-0.1063	Yes
224	CPE			24236	-5.705	-0.1045	Yes
225	KLF9			24326	-6.110	-0.1043	Yes
226	CYP1B1			24480	-6.654	-0.1065	Yes
227	RORA			24535	-6.926	-0.1049	Yes
228	ECHDC3			24539	-6.952	-0.1014	Yes
229	LDB3			24563	-7.067	-0.0986	Yes
230	FAM20A			24577	-7.134	-0.0955	Yes
231	C16orf89			24712	-7.718	-0.0970	Yes
232	CLDN10			24736	-7.854	-0.0942	Yes
233	ITM2A			24748	-7.957	-0.0910	Yes
234	HMGN5			24926	-9.077	-0.0941	Yes
235	CHRM3			25024	-9.924	-0.0942	Yes
236	FAM107A			25030	-10.032	-0.0907	Yes
237	CD36			25052	-10.178	-0.0879	Yes
238	DMD			25205	-11.618	-0.0901	Yes
239	DUSP5			25225	-11.830	-0.0872	Yes
240	NDNF			25228	-11.869	-0.0836	Yes
241	GPM6B			25244	-11.974	-0.0805	Yes
242	MUM1L1			25261	-12.127	-0.0775	Yes
243	CNTN1			25362	-13.471	-0.0777	Yes
244	UBE2QL1			25363	-13.491	-0.0740	Yes
245	CXCL12			25372	-13.621	-0.0707	Yes
246	SUSD4			25416	-14.162	-0.0687	Yes
247	COL4A6			25422	-14.248	-0.0652	Yes
248	SERPINI1			25428	-14.339	-0.0618	Yes
249	PID1			25462	-14.835	-0.0594	Yes
250	STOX2			25537	-16.055	-0.0586	Yes
251	ZNF844			25616	-18.049	-0.0579	Yes
252	LARP6			25627	-18.258	-0.0546	Yes
253	MAP7D2			25707	-20.168	-0.0540	Yes
254	MT1E			25733	-20.906	-0.0513	Yes
255	F13A1			25739	-21.210	-0.0479	Yes
256	MAOA			25755	-21.638	-0.0448	Yes
257	ELL2			25886	-26.509	-0.0461	Yes
258	NTRK3			25906	-27.988	-0.0432	Yes
259	SHISA3			25921	-28.773	-0.0401	Yes
260	NR3C1			25926	-29.242	-0.0366	Yes
261	NCAM1			25964	-31.402	-0.0344	Yes
262	SLIT2			25966	-31.492	-0.0308	Yes
263	BCHE			26012	-34.895	-0.0289	Yes
264	HSPB8			26026	-36.409	-0.0257	Yes
265	ATP1A2			26137	-49.083	-0.0263	Yes
266	RIMS3			26155	-52.334	-0.0233	Yes
267	VLDLR			26190	-59.843	-0.0209	Yes
268	ARRDC4			26217	-70.088	-0.0183	Yes
269	MDFIC			26218	-70.415	-0.0146	Yes
270	MT1F			26271	-107.226	-0.0130	Yes
271	ALDH1L2			26287	-152.864	-0.0099	Yes
272	CHGA			26292	-180.006	-0.0064	Yes
273	MT1X			26307	-290.514	-0.0033	Yes
274	TSC22D3			26317	-299.207	-0.0000	Yes

Fig 2: VECCHI_GASTRIC_CANCER_EARLY_DN: Random ES distribution   
Gene set null distribution of ES for VECCHI_GASTRIC_CANCER_EARLY_DN