Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | SMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls #del_versus_fl.SMCHD1_KO.cls #del_versus_fl_repos |
| Phenotype | SMCHD1_KO.cls#del_versus_fl_repos |
| Upregulated in class | 1 |
| GeneSet | DAUER_STAT3_TARGETS_DN |
| Enrichment Score (ES) | -0.81749946 |
| Normalized Enrichment Score (NES) | -1.8505177 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.0952652E-4 |
| FWER p-Value | 0.007 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IFITM1 | IFITM1 Entrez, Source | interferon induced transmembrane protein 1 (9-27) | 995 | 0.299 | -0.0283 | No |
| 2 | LAMP3 | LAMP3 Entrez, Source | lysosomal-associated membrane protein 3 | 1475 | 0.233 | -0.0389 | No |
| 3 | GRB14 | GRB14 Entrez, Source | growth factor receptor-bound protein 14 | 2611 | 0.148 | -0.0777 | No |
| 4 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 4303 | 0.075 | -0.1405 | No |
| 5 | TMEM97 | TMEM97 Entrez, Source | transmembrane protein 97 | 8517 | 0.064 | -0.3013 | No |
| 6 | PGRMC2 | PGRMC2 Entrez, Source | progesterone receptor membrane component 2 | 8625 | 0.061 | -0.3033 | No |
| 7 | SP110 | SP110 Entrez, Source | SP110 nuclear body protein | 9080 | 0.057 | -0.3190 | No |
| 8 | OAS3 | OAS3 Entrez, Source | 2'-5'-oligoadenylate synthetase 3, 100kDa | 9242 | 0.055 | -0.3233 | No |
| 9 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 9593 | 0.049 | -0.3352 | No |
| 10 | TDRD7 | TDRD7 Entrez, Source | tudor domain containing 7 | 10188 | 0.041 | -0.3568 | No |
| 11 | TNFSF10 | TNFSF10 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 10 | 10244 | 0.040 | -0.3575 | No |
| 12 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 11434 | 0.025 | -0.4026 | No |
| 13 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 11493 | 0.025 | -0.4040 | No |
| 14 | BCL2L13 | BCL2L13 Entrez, Source | BCL2-like 13 (apoptosis facilitator) | 12500 | 0.012 | -0.4425 | No |
| 15 | ST8SIA4 | ST8SIA4 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 12951 | 0.007 | -0.4597 | No |
| 16 | TRIM14 | TRIM14 Entrez, Source | tripartite motif-containing 14 | 14280 | -0.009 | -0.5107 | No |
| 17 | HEXIM1 | HEXIM1 Entrez, Source | hexamethylene bis-acetamide inducible 1 | 14594 | -0.013 | -0.5224 | No |
| 18 | DNAJB4 | DNAJB4 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 4 | 19768 | -0.131 | -0.7180 | No |
| 19 | HSPA1A | HSPA1A Entrez, Source | heat shock 70kDa protein 1A | 21552 | -0.228 | -0.7792 | No |
| 20 | HSPA1B | HSPA1B Entrez, Source | heat shock 70kDa protein 1B | 21737 | -0.242 | -0.7780 | No |
| 21 | HERC6 | HERC6 Entrez, Source | hect domain and RLD 6 | 21820 | -0.248 | -0.7727 | No |
| 22 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 21911 | -0.256 | -0.7675 | No |
| 23 | AQP3 | AQP3 Entrez, Source | aquaporin 3 (Gill blood group) | 22134 | -0.272 | -0.7668 | No |
| 24 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 23259 | -0.399 | -0.7966 | Yes |
| 25 | TRIM5 | TRIM5 Entrez, Source | tripartite motif-containing 5 | 23487 | -0.433 | -0.7907 | Yes |
| 26 | PARP12 | PARP12 Entrez, Source | poly (ADP-ribose) polymerase family, member 12 | 23548 | -0.441 | -0.7780 | Yes |
| 27 | DDX58 | DDX58 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 24122 | -0.545 | -0.7815 | Yes |
| 28 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 25053 | -0.849 | -0.7886 | Yes |
| 29 | TRANK1 | 25274 | -0.982 | -0.7636 | Yes | ||
| 30 | TLR3 | TLR3 Entrez, Source | toll-like receptor 3 | 25298 | -1.003 | -0.7303 | Yes |
| 31 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 25437 | -1.129 | -0.6971 | Yes |
| 32 | OAS2 | OAS2 Entrez, Source | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 25558 | -1.284 | -0.6580 | Yes |
| 33 | IFI35 | IFI35 Entrez, Source | interferon-induced protein 35 | 25621 | -1.385 | -0.6132 | Yes |
| 34 | ISG15 | ISG15 Entrez, Source | ISG15 ubiquitin-like modifier | 25699 | -1.594 | -0.5619 | Yes |
| 35 | DDX60 | 25710 | -1.643 | -0.5062 | Yes | ||
| 36 | IRF7 | IRF7 Entrez, Source | interferon regulatory factor 7 | 25794 | -2.009 | -0.4410 | Yes |
| 37 | IFIH1 | IFIH1 Entrez, Source | interferon induced with helicase C domain 1 | 25804 | -2.052 | -0.3714 | Yes |
| 38 | USP18 | USP18 Entrez, Source | ubiquitin specific peptidase 18 | 25830 | -2.231 | -0.2963 | Yes |
| 39 | IFI44 | IFI44 Entrez, Source | interferon-induced protein 44 | 25831 | -2.278 | -0.2186 | Yes |
| 40 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 25844 | -2.414 | -0.1368 | Yes |
| 41 | IFIT1 | IFIT1 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 1 | 25894 | -4.073 | 0.0002 | Yes |
