Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | SMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls #del_versus_fl.SMCHD1_KO.cls #del_versus_fl_repos |
| Phenotype | SMCHD1_KO.cls#del_versus_fl_repos |
| Upregulated in class | 0 |
| GeneSet | GCM_RAP2A |
| Enrichment Score (ES) | 0.5650776 |
| Normalized Enrichment Score (NES) | 1.8188852 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.24840192 |
| FWER p-Value | 0.97 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GABBR2 | GABBR2 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 2 | 130 | 0.714 | 0.2839 | Yes |
| 2 | ZFP14 | ZFP14 Entrez, Source | zinc finger protein 14 homolog (mouse) | 138 | 0.695 | 0.5651 | Yes |
| 3 | NGRN | NGRN Entrez, Source | neugrin, neurite outgrowth associated | 2838 | 0.132 | 0.5143 | No |
| 4 | ABI2 | ABI2 Entrez, Source | abl interactor 2 | 8904 | 0.060 | 0.3041 | No |
| 5 | ADO | 9582 | 0.049 | 0.2979 | No | ||
| 6 | PHF2 | PHF2 Entrez, Source | PHD finger protein 2 | 9626 | 0.049 | 0.3159 | No |
| 7 | RAN | RAN Entrez, Source | RAN, member RAS oncogene family | 10062 | 0.043 | 0.3164 | No |
| 8 | IPO7 | IPO7 Entrez, Source | importin 7 | 10227 | 0.040 | 0.3263 | No |
| 9 | SPIRE1 | SPIRE1 Entrez, Source | spire homolog 1 (Drosophila) | 10396 | 0.038 | 0.3352 | No |
| 10 | TUBGCP3 | TUBGCP3 Entrez, Source | tubulin, gamma complex associated protein 3 | 10532 | 0.036 | 0.3446 | No |
| 11 | SMAP1 | SMAP1 Entrez, Source | stromal membrane-associated protein 1 | 10707 | 0.034 | 0.3516 | No |
| 12 | NAB1 | NAB1 Entrez, Source | NGFI-A binding protein 1 (EGR1 binding protein 1) | 10754 | 0.033 | 0.3634 | No |
| 13 | RAB10 | RAB10 Entrez, Source | RAB10, member RAS oncogene family | 10771 | 0.033 | 0.3762 | No |
| 14 | CAND1 | CAND1 Entrez, Source | cullin-associated and neddylation-dissociated 1 | 10893 | 0.032 | 0.3843 | No |
| 15 | UBQLN1 | UBQLN1 Entrez, Source | ubiquilin 1 | 10902 | 0.031 | 0.3967 | No |
| 16 | FBXW11 | FBXW11 Entrez, Source | F-box and WD-40 domain protein 11 | 11688 | 0.023 | 0.3755 | No |
| 17 | CCDC88A | 11745 | 0.022 | 0.3822 | No | ||
| 18 | ENAH | ENAH Entrez, Source | enabled homolog (Drosophila) | 11776 | 0.022 | 0.3898 | No |
| 19 | TMEM30A | TMEM30A Entrez, Source | transmembrane protein 30A | 12098 | 0.018 | 0.3845 | No |
| 20 | SOX5 | SOX5 Entrez, Source | SRY (sex determining region Y)-box 5 | 12572 | 0.012 | 0.3710 | No |
| 21 | HMBOX1 | HMBOX1 Entrez, Source | homeobox containing 1 | 12631 | 0.011 | 0.3732 | No |
| 22 | ZFAND3 | ZFAND3 Entrez, Source | zinc finger, AN1-type domain 3 | 12644 | 0.011 | 0.3771 | No |
| 23 | PHYHIPL | PHYHIPL Entrez, Source | phytanoyl-CoA 2-hydroxylase interacting protein-like | 13051 | 0.006 | 0.3638 | No |
| 24 | SNX27 | SNX27 Entrez, Source | sorting nexin family member 27 | 13313 | 0.003 | 0.3549 | No |
| 25 | RALGAPA1 | 13349 | 0.002 | 0.3545 | No | ||
| 26 | SPAG9 | SPAG9 Entrez, Source | sperm associated antigen 9 | 13586 | -0.001 | 0.3456 | No |
| 27 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 14107 | -0.006 | 0.3281 | No |
| 28 | CEP350 | CEP350 Entrez, Source | centrosomal protein 350kDa | 14178 | -0.007 | 0.3284 | No |
| 29 | RAP2A | RAP2A Entrez, Source | RAP2A, member of RAS oncogene family | 14471 | -0.012 | 0.3219 | No |
| 30 | TEAD1 | TEAD1 Entrez, Source | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 14840 | -0.017 | 0.3146 | No |
| 31 | KIDINS220 | KIDINS220 Entrez, Source | - | 16419 | -0.038 | 0.2689 | No |
| 32 | MTMR1 | MTMR1 Entrez, Source | myotubularin related protein 1 | 17444 | -0.058 | 0.2526 | No |
| 33 | LRRC8A | LRRC8A Entrez, Source | leucine rich repeat containing 8 family, member A | 18332 | -0.080 | 0.2506 | No |
| 34 | CLEC16A | 19088 | -0.103 | 0.2633 | No |
