DatasetSMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls
#del_versus_fl.SMCHD1_KO.cls
#del_versus_fl_repos
PhenotypeSMCHD1_KO.cls#del_versus_fl_repos
Upregulated in class0
GeneSetGNF2_BUB1B
Enrichment Score (ES)0.54122794
Normalized Enrichment Score (NES)1.8582426
Nominal p-value0.0
FDR q-value0.212942
FWER p-Value0.883
Table: GSEA Results Summary



Fig 1: Enrichment plot: GNF2_BUB1B   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ASF1BASF1B
Entrez,  Source
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)14590.2340.0202Yes
2GINS1GINS1
Entrez,  Source
GINS complex subunit 1 (Psf1 homolog)18000.1950.0709Yes
3TYMSTYMS
Entrez,  Source
thymidylate synthetase25050.1500.0930Yes
4NDC8030310.1200.1120Yes
5TTKTTK
Entrez,  Source
TTK protein kinase30420.1190.1506Yes
6BUB1BUB1
Entrez,  Source
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast)32610.1070.1774Yes
7GMNNGMNN
Entrez,  Source
geminin, DNA replication inhibitor33700.1020.2067Yes
8CEP55CEP55
Entrez,  Source
centrosomal protein 55kDa35140.0970.2328Yes
9HELLSHELLS
Entrez,  Source
helicase, lymphoid-specific35420.0950.2629Yes
10SMC4SMC4
Entrez,  Source
structural maintenance of chromosomes 437170.0880.2852Yes
11AURKAAURKA
Entrez,  Source
aurora kinase A37500.0870.3125Yes
12CCNA2CCNA2
Entrez,  Source
cyclin A279990.0730.1722Yes
13UBE2CUBE2C
Entrez,  Source
ubiquitin-conjugating enzyme E2C80180.0720.1953Yes
14MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase82360.0690.2096Yes
15CDCA8CDCA8
Entrez,  Source
cell division cycle associated 885110.0640.2200Yes
16MCM4MCM4
Entrez,  Source
MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)85820.0620.2377Yes
17PLK1PLK1
Entrez,  Source
polo-like kinase 1 (Drosophila)86880.0600.2534Yes
18KIF14KIF14
Entrez,  Source
kinesin family member 1486950.0600.2729Yes
19CSE1LCSE1L
Entrez,  Source
CSE1 chromosome segregation 1-like (yeast)89480.0590.2825Yes
20LMNB1LMNB1
Entrez,  Source
lamin B189510.0590.3017Yes
21RRM1RRM1
Entrez,  Source
ribonucleotide reductase M1 polypeptide91370.0560.3128Yes
22HMMRHMMR
Entrez,  Source
hyaluronan-mediated motility receptor (RHAMM)91730.0550.3295Yes
23RACGAP1RACGAP1
Entrez,  Source
Rac GTPase activating protein 192530.0550.3443Yes
24TOP2ATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa92700.0540.3615Yes
25PAICSPAICS
Entrez,  Source
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase93430.0530.3760Yes
26CCNB2CCNB2
Entrez,  Source
cyclin B294530.0510.3886Yes
27MCM3MCM3
Entrez,  Source
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)96110.0490.3986Yes
28KIF11KIF11
Entrez,  Source
kinesin family member 1196520.0480.4128Yes
29ASPMASPM
Entrez,  Source
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)97110.0470.4261Yes
30AURKBAURKB
Entrez,  Source
aurora kinase B97470.0470.4402Yes
31NASPNASP
Entrez,  Source
nuclear autoantigenic sperm protein (histone-binding)97570.0470.4552Yes
32FANCIFANCI
Entrez,  Source
Fanconi anemia, complementation group I99240.0450.4634Yes
33POLD1POLD1
Entrez,  Source
polymerase (DNA directed), delta 1, catalytic subunit 125kDa100860.0420.4711Yes
34TCP1TCP1
Entrez,  Source
t-complex 1101560.0410.4820Yes
35BUB1BBUB1B
Entrez,  Source
BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)104370.0370.4834Yes
36KIF20AKIF20A
Entrez,  Source
kinesin family member 20A106040.0350.4885Yes
37MCM2MCM2
Entrez,  Source
MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)106800.0340.4969Yes
38NCAPD2NCAPD2
Entrez,  Source
non-SMC condensin I complex, subunit D2108920.0320.4991Yes
39PCNAPCNA
Entrez,  Source
proliferating cell nuclear antigen109390.0310.5075Yes
40CDC20CDC20
Entrez,  Source
CDC20 cell division cycle 20 homolog (S. cerevisiae)109500.0310.5172Yes
41PA2G4PA2G4
Entrez,  Source
proliferation-associated 2G4, 38kDa111000.0290.5211Yes
42RRM2RRM2
Entrez,  Source
ribonucleotide reductase M2 polypeptide111960.0280.5266Yes
43HJURP112620.0270.5331Yes
44MRPL39MRPL39
Entrez,  Source
mitochondrial ribosomal protein L39113620.0260.5379Yes
45NUP205NUP205
Entrez,  Source
nucleoporin 205kDa115830.0240.5372Yes
46ESPL1ESPL1
Entrez,  Source
extra spindle poles like 1 (S. cerevisiae)116720.0230.5412Yes
47CENPMCENPM
Entrez,  Source
centromere protein M122200.0160.5253No
48SPAG5SPAG5
Entrez,  Source
sperm associated antigen 513814-0.0030.4647No
49ZWINTZWINT
Entrez,  Source
ZW10 interactor14235-0.0080.4512No
Table: GSEA details [plain text format]



Fig 2: GNF2_BUB1B   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GNF2_BUB1B: Random ES distribution   
Gene set null distribution of ES for GNF2_BUB1B