DatasetSMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls
#del_versus_fl.SMCHD1_KO.cls
#del_versus_fl_repos
PhenotypeSMCHD1_KO.cls#del_versus_fl_repos
Upregulated in class0
GeneSetGNF2_CCNA2
Enrichment Score (ES)0.5309702
Normalized Enrichment Score (NES)1.9159663
Nominal p-value0.0
FDR q-value0.19251941
FWER p-Value0.707
Table: GSEA Results Summary



Fig 1: Enrichment plot: GNF2_CCNA2   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ASF1BASF1B
Entrez,  Source
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)14590.2340.0020Yes
2TYMSTYMS
Entrez,  Source
thymidylate synthetase25050.150-0.0009Yes
3RAD51AP1RAD51AP1
Entrez,  Source
RAD51 associated protein 126260.1460.0310Yes
4CKS1BCKS1B
Entrez,  Source
CDC28 protein kinase regulatory subunit 1B29420.1250.0502Yes
5NDC8030310.1200.0767Yes
6TTKTTK
Entrez,  Source
TTK protein kinase30420.1190.1061Yes
7SHCBP1SHCBP1
Entrez,  Source
SHC SH2-domain binding protein 132020.1100.1275Yes
8PRIM1PRIM1
Entrez,  Source
primase, polypeptide 1, 49kDa32680.1070.1517Yes
9RFC4RFC4
Entrez,  Source
replication factor C (activator 1) 4, 37kDa32990.1050.1768Yes
10GMNNGMNN
Entrez,  Source
geminin, DNA replication inhibitor33700.1020.1996Yes
11NCAPGNCAPG
Entrez,  Source
non-SMC condensin I complex, subunit G36630.0900.2109Yes
12BIRC5BIRC5
Entrez,  Source
baculoviral IAP repeat-containing 5 (survivin)36910.0900.2322Yes
13SMC4SMC4
Entrez,  Source
structural maintenance of chromosomes 437170.0880.2533Yes
14AURKAAURKA
Entrez,  Source
aurora kinase A37500.0870.2739Yes
15CENPACENPA
Entrez,  Source
centromere protein A40320.0840.2840Yes
16MCM6MCM6
Entrez,  Source
MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)42760.0760.2936Yes
17CCNA2CCNA2
Entrez,  Source
cyclin A279990.0730.1678Yes
18E2F8E2F8
Entrez,  Source
E2F transcription factor 880040.0730.1859Yes
19UBE2CUBE2C
Entrez,  Source
ubiquitin-conjugating enzyme E2C80180.0720.2036Yes
20NUSAP1NUSAP1
Entrez,  Source
nucleolar and spindle associated protein 181790.0710.2150Yes
21TMPOTMPO
Entrez,  Source
thymopoietin82070.0700.2314Yes
22MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase82360.0690.2476Yes
23DLGAP583190.0680.2615Yes
24SMC2SMC2
Entrez,  Source
structural maintenance of chromosomes 283520.0670.2770Yes
25CDCA8CDCA8
Entrez,  Source
cell division cycle associated 885110.0640.2869Yes
26CDK185480.0630.3012Yes
27TPX2TPX2
Entrez,  Source
TPX2, microtubule-associated, homolog (Xenopus laevis)85810.0620.3155Yes
28MCM4MCM4
Entrez,  Source
MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)85820.0620.3311Yes
29EZH2EZH2
Entrez,  Source
enhancer of zeste homolog 2 (Drosophila)86260.0610.3447Yes
30PLK1PLK1
Entrez,  Source
polo-like kinase 1 (Drosophila)86880.0600.3575Yes
31KIF14KIF14
Entrez,  Source
kinesin family member 1486950.0600.3723Yes
32KIF18B89190.0600.3785Yes
33RRM1RRM1
Entrez,  Source
ribonucleotide reductase M1 polypeptide91370.0560.3841Yes
34HMMRHMMR
Entrez,  Source
hyaluronan-mediated motility receptor (RHAMM)91730.0550.3965Yes
35RACGAP1RACGAP1
Entrez,  Source
Rac GTPase activating protein 192530.0550.4071Yes
36TOP2ATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa92700.0540.4200Yes
37CCNB2CCNB2
Entrez,  Source
cyclin B294530.0510.4257Yes
38CENPECENPE
Entrez,  Source
centromere protein E, 312kDa95480.0500.4345Yes
39MCM3MCM3
Entrez,  Source
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)96110.0490.4443Yes
40KIF11KIF11
Entrez,  Source
kinesin family member 1196520.0480.4549Yes
41ASPMASPM
Entrez,  Source
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)97110.0470.4645Yes
42AURKBAURKB
Entrez,  Source
aurora kinase B97470.0470.4748Yes
43FANCIFANCI
Entrez,  Source
Fanconi anemia, complementation group I99240.0450.4792Yes
44MCM7MCM7
Entrez,  Source
MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)99930.0440.4875Yes
45HMGB2HMGB2
Entrez,  Source
high-mobility group box 2101070.0420.4936Yes
46CDCA3CDCA3
Entrez,  Source
cell division cycle associated 3102120.0410.4997Yes
47BUB1BBUB1B
Entrez,  Source
BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)104370.0370.5004Yes
48KIF20AKIF20A
Entrez,  Source
kinesin family member 20A106040.0350.5028Yes
49MCM2MCM2
Entrez,  Source
MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)106800.0340.5085Yes
50NCAPD2NCAPD2
Entrez,  Source
non-SMC condensin I complex, subunit D2108920.0320.5082Yes
51PCNAPCNA
Entrez,  Source
proliferating cell nuclear antigen109390.0310.5142Yes
52CDC20CDC20
Entrez,  Source
CDC20 cell division cycle 20 homolog (S. cerevisiae)109500.0310.5215Yes
53RFC3RFC3
Entrez,  Source
replication factor C (activator 1) 3, 38kDa110330.0300.5258Yes
54RRM2RRM2
Entrez,  Source
ribonucleotide reductase M2 polypeptide111960.0280.5266Yes
55HJURP112620.0270.5310Yes
56PRC1PRC1
Entrez,  Source
protein regulator of cytokinesis 1116660.0230.5211No
57ESPL1ESPL1
Entrez,  Source
extra spindle poles like 1 (S. cerevisiae)116720.0230.5265No
58FOXM1FOXM1
Entrez,  Source
forkhead box M1118220.0210.5260No
59CKS2CKS2
Entrez,  Source
CDC28 protein kinase regulatory subunit 2122170.0160.5148No
60FEN1FEN1
Entrez,  Source
flap structure-specific endonuclease 1126460.0110.5009No
61CENPFCENPF
Entrez,  Source
centromere protein F, 350/400ka (mitosin)134660.0010.4694No
62H2AFXH2AFX
Entrez,  Source
H2A histone family, member X14049-0.0060.4484No
63ZWINTZWINT
Entrez,  Source
ZW10 interactor14235-0.0080.4433No
64GINS2GINS2
Entrez,  Source
GINS complex subunit 2 (Psf2 homolog)14397-0.0110.4397No
65MKI67MKI67
Entrez,  Source
antigen identified by monoclonal antibody Ki-6715149-0.0220.4161No
Table: GSEA details [plain text format]



Fig 2: GNF2_CCNA2   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GNF2_CCNA2: Random ES distribution   
Gene set null distribution of ES for GNF2_CCNA2