| Dataset | SMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls #del_versus_fl.SMCHD1_KO.cls #del_versus_fl_repos |
| Phenotype | SMCHD1_KO.cls#del_versus_fl_repos |
| Upregulated in class | 0 |
| GeneSet | GNF2_CKS1B |
| Enrichment Score (ES) | 0.5524962 |
| Normalized Enrichment Score (NES) | 1.8316392 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.23435396 |
| FWER p-Value | 0.945 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ASF1B | ASF1B Entrez,  Source | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 1459 | 0.234 | 0.0361 | Yes |
| 2 | RPA3 | RPA3 Entrez,  Source | replication protein A3, 14kDa | 1886 | 0.184 | 0.0925 | Yes |
| 3 | TRIP13 | TRIP13 Entrez,  Source | thyroid hormone receptor interactor 13 | 2702 | 0.141 | 0.1170 | Yes |
| 4 | CKS1B | CKS1B Entrez,  Source | CDC28 protein kinase regulatory subunit 1B | 2942 | 0.125 | 0.1574 | Yes |
| 5 | NDC80 | 3031 | 0.120 | 0.2014 | Yes | ||
| 6 | BUB1 | BUB1 Entrez,  Source | BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) | 3261 | 0.107 | 0.2351 | Yes |
| 7 | RFC4 | RFC4 Entrez,  Source | replication factor C (activator 1) 4, 37kDa | 3299 | 0.105 | 0.2753 | Yes |
| 8 | BIRC5 | BIRC5 Entrez,  Source | baculoviral IAP repeat-containing 5 (survivin) | 3691 | 0.090 | 0.2956 | Yes |
| 9 | KIF2C | KIF2C Entrez,  Source | kinesin family member 2C | 4267 | 0.076 | 0.3036 | Yes |
| 10 | MCM6 | MCM6 Entrez,  Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 4276 | 0.076 | 0.3334 | Yes |
| 11 | CCNA2 | CCNA2 Entrez,  Source | cyclin A2 | 7999 | 0.073 | 0.2184 | Yes |
| 12 | UBE2C | UBE2C Entrez,  Source | ubiquitin-conjugating enzyme E2C | 8018 | 0.072 | 0.2464 | Yes |
| 13 | MELK | MELK Entrez,  Source | maternal embryonic leucine zipper kinase | 8236 | 0.069 | 0.2655 | Yes |
| 14 | SMC2 | SMC2 Entrez,  Source | structural maintenance of chromosomes 2 | 8352 | 0.067 | 0.2876 | Yes |
| 15 | CDCA8 | CDCA8 Entrez,  Source | cell division cycle associated 8 | 8511 | 0.064 | 0.3068 | Yes |
| 16 | GMPS | GMPS Entrez,  Source | guanine monphosphate synthetase | 8550 | 0.063 | 0.3302 | Yes |
| 17 | TPX2 | TPX2 Entrez,  Source | TPX2, microtubule-associated, homolog (Xenopus laevis) | 8581 | 0.062 | 0.3537 | Yes |
| 18 | RNASEH2A | RNASEH2A Entrez,  Source | ribonuclease H2, subunit A | 8648 | 0.061 | 0.3753 | Yes |
| 19 | RANBP1 | RANBP1 Entrez,  Source | RAN binding protein 1 | 9100 | 0.057 | 0.3802 | Yes |
| 20 | PAICS | PAICS Entrez,  Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 9343 | 0.053 | 0.3918 | Yes |
| 21 | CENPE | CENPE Entrez,  Source | centromere protein E, 312kDa | 9548 | 0.050 | 0.4036 | Yes |
| 22 | MCM3 | MCM3 Entrez,  Source | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) | 9611 | 0.049 | 0.4205 | Yes |
| 23 | KIF11 | KIF11 Entrez,  Source | kinesin family member 11 | 9652 | 0.048 | 0.4381 | Yes |
| 24 | ASPM | ASPM Entrez,  Source | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 9711 | 0.047 | 0.4546 | Yes |
| 25 | AURKB | AURKB Entrez,  Source | aurora kinase B | 9747 | 0.047 | 0.4718 | Yes |
| 26 | MRPL35 | MRPL35 Entrez,  Source | mitochondrial ribosomal protein L35 | 9864 | 0.046 | 0.4853 | Yes |
| 27 | RAN | RAN Entrez,  Source | RAN, member RAS oncogene family | 10062 | 0.043 | 0.4946 | Yes |
| 28 | TCP1 | TCP1 Entrez,  Source | t-complex 1 | 10156 | 0.041 | 0.5074 | Yes |
| 29 | KIF20A | KIF20A Entrez,  Source | kinesin family member 20A | 10604 | 0.035 | 0.5041 | Yes |
| 30 | NCAPD2 | NCAPD2 Entrez,  Source | non-SMC condensin I complex, subunit D2 | 10892 | 0.032 | 0.5055 | Yes |
| 31 | CDC20 | CDC20 Entrez,  Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 10950 | 0.031 | 0.5155 | Yes |
| 32 | RFC3 | RFC3 Entrez,  Source | replication factor C (activator 1) 3, 38kDa | 11033 | 0.030 | 0.5242 | Yes |
| 33 | PA2G4 | PA2G4 Entrez,  Source | proliferation-associated 2G4, 38kDa | 11100 | 0.029 | 0.5333 | Yes |
| 34 | IARS | IARS Entrez,  Source | isoleucine-tRNA synthetase | 11126 | 0.029 | 0.5438 | Yes |
| 35 | ATIC | ATIC Entrez,  Source | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | 11191 | 0.028 | 0.5525 | Yes |
| 36 | ESPL1 | ESPL1 Entrez,  Source | extra spindle poles like 1 (S. cerevisiae) | 11672 | 0.023 | 0.5429 | No |
| 37 | CCT4 | CCT4 Entrez,  Source | chaperonin containing TCP1, subunit 4 (delta) | 12054 | 0.018 | 0.5353 | No |

