DatasetSMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls
#del_versus_fl.SMCHD1_KO.cls
#del_versus_fl_repos
PhenotypeSMCHD1_KO.cls#del_versus_fl_repos
Upregulated in class0
GeneSetGNF2_CKS1B
Enrichment Score (ES)0.5524962
Normalized Enrichment Score (NES)1.8316392
Nominal p-value0.0
FDR q-value0.23435396
FWER p-Value0.945
Table: GSEA Results Summary



Fig 1: Enrichment plot: GNF2_CKS1B   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ASF1BASF1B
Entrez,  Source
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)14590.2340.0361Yes
2RPA3RPA3
Entrez,  Source
replication protein A3, 14kDa18860.1840.0925Yes
3TRIP13TRIP13
Entrez,  Source
thyroid hormone receptor interactor 1327020.1410.1170Yes
4CKS1BCKS1B
Entrez,  Source
CDC28 protein kinase regulatory subunit 1B29420.1250.1574Yes
5NDC8030310.1200.2014Yes
6BUB1BUB1
Entrez,  Source
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast)32610.1070.2351Yes
7RFC4RFC4
Entrez,  Source
replication factor C (activator 1) 4, 37kDa32990.1050.2753Yes
8BIRC5BIRC5
Entrez,  Source
baculoviral IAP repeat-containing 5 (survivin)36910.0900.2956Yes
9KIF2CKIF2C
Entrez,  Source
kinesin family member 2C42670.0760.3036Yes
10MCM6MCM6
Entrez,  Source
MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)42760.0760.3334Yes
11CCNA2CCNA2
Entrez,  Source
cyclin A279990.0730.2184Yes
12UBE2CUBE2C
Entrez,  Source
ubiquitin-conjugating enzyme E2C80180.0720.2464Yes
13MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase82360.0690.2655Yes
14SMC2SMC2
Entrez,  Source
structural maintenance of chromosomes 283520.0670.2876Yes
15CDCA8CDCA8
Entrez,  Source
cell division cycle associated 885110.0640.3068Yes
16GMPSGMPS
Entrez,  Source
guanine monphosphate synthetase85500.0630.3302Yes
17TPX2TPX2
Entrez,  Source
TPX2, microtubule-associated, homolog (Xenopus laevis)85810.0620.3537Yes
18RNASEH2ARNASEH2A
Entrez,  Source
ribonuclease H2, subunit A86480.0610.3753Yes
19RANBP1RANBP1
Entrez,  Source
RAN binding protein 191000.0570.3802Yes
20PAICSPAICS
Entrez,  Source
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase93430.0530.3918Yes
21CENPECENPE
Entrez,  Source
centromere protein E, 312kDa95480.0500.4036Yes
22MCM3MCM3
Entrez,  Source
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)96110.0490.4205Yes
23KIF11KIF11
Entrez,  Source
kinesin family member 1196520.0480.4381Yes
24ASPMASPM
Entrez,  Source
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)97110.0470.4546Yes
25AURKBAURKB
Entrez,  Source
aurora kinase B97470.0470.4718Yes
26MRPL35MRPL35
Entrez,  Source
mitochondrial ribosomal protein L3598640.0460.4853Yes
27RANRAN
Entrez,  Source
RAN, member RAS oncogene family100620.0430.4946Yes
28TCP1TCP1
Entrez,  Source
t-complex 1101560.0410.5074Yes
29KIF20AKIF20A
Entrez,  Source
kinesin family member 20A106040.0350.5041Yes
30NCAPD2NCAPD2
Entrez,  Source
non-SMC condensin I complex, subunit D2108920.0320.5055Yes
31CDC20CDC20
Entrez,  Source
CDC20 cell division cycle 20 homolog (S. cerevisiae)109500.0310.5155Yes
32RFC3RFC3
Entrez,  Source
replication factor C (activator 1) 3, 38kDa110330.0300.5242Yes
33PA2G4PA2G4
Entrez,  Source
proliferation-associated 2G4, 38kDa111000.0290.5333Yes
34IARSIARS
Entrez,  Source
isoleucine-tRNA synthetase111260.0290.5438Yes
35ATICATIC
Entrez,  Source
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase111910.0280.5525Yes
36ESPL1ESPL1
Entrez,  Source
extra spindle poles like 1 (S. cerevisiae)116720.0230.5429No
37CCT4CCT4
Entrez,  Source
chaperonin containing TCP1, subunit 4 (delta)120540.0180.5353No
Table: GSEA details [plain text format]



Fig 2: GNF2_CKS1B   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GNF2_CKS1B: Random ES distribution   
Gene set null distribution of ES for GNF2_CKS1B