Details for gene set GNF2_PCNA[GSEA]

Table: GSEA Results Summary

Dataset	SMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls #del_versus_fl.SMCHD1_KO.cls #del_versus_fl_repos
Phenotype	SMCHD1_KO.cls#del_versus_fl_repos
Upregulated in class	0
GeneSet	GNF2_PCNA
Enrichment Score (ES)	0.52445
Normalized Enrichment Score (NES)	1.8589573
Nominal p-value	0.0
FDR q-value	0.2283703
FWER p-Value	0.881

Fig 1: Enrichment plot: GNF2_PCNA   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GINS1	GINS1 Entrez,  Source	GINS complex subunit 1 (Psf1 homolog)	1800	0.195	-0.0226	Yes
2	TYMS	TYMS Entrez,  Source	thymidylate synthetase	2505	0.150	-0.0135	Yes
3	RAD51AP1	RAD51AP1 Entrez,  Source	RAD51 associated protein 1	2626	0.146	0.0172	Yes
4	POLE2	POLE2 Entrez,  Source	polymerase (DNA directed), epsilon 2 (p59 subunit)	2630	0.146	0.0524	Yes
5	NDC80			3031	0.120	0.0659	Yes
6	TTK	TTK Entrez,  Source	TTK protein kinase	3042	0.119	0.0943	Yes
7	SHCBP1	SHCBP1 Entrez,  Source	SHC SH2-domain binding protein 1	3202	0.110	0.1148	Yes
8	PLK4	PLK4 Entrez,  Source	polo-like kinase 4 (Drosophila)	3251	0.108	0.1390	Yes
9	PRIM1	PRIM1 Entrez,  Source	primase, polypeptide 1, 49kDa	3268	0.107	0.1642	Yes
10	RFC4	RFC4 Entrez,  Source	replication factor C (activator 1) 4, 37kDa	3299	0.105	0.1884	Yes
11	KIF15	KIF15 Entrez,  Source	kinesin family member 15	3309	0.105	0.2134	Yes
12	GMNN	GMNN Entrez,  Source	geminin, DNA replication inhibitor	3370	0.102	0.2357	Yes
13	VRK1	VRK1 Entrez,  Source	vaccinia related kinase 1	3639	0.091	0.2474	Yes
14	BIRC5	BIRC5 Entrez,  Source	baculoviral IAP repeat-containing 5 (survivin)	3691	0.090	0.2671	Yes
15	DTL	DTL Entrez,  Source	denticleless homolog (Drosophila)	3696	0.089	0.2885	Yes
16	SMC4	SMC4 Entrez,  Source	structural maintenance of chromosomes 4	3717	0.088	0.3091	Yes
17	AURKA	AURKA Entrez,  Source	aurora kinase A	3750	0.087	0.3290	Yes
18	MCM6	MCM6 Entrez,  Source	MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)	4276	0.076	0.3270	Yes
19	SLBP	SLBP Entrez,  Source	stem-loop (histone) binding protein	7995	0.073	0.2008	Yes
20	CCNA2	CCNA2 Entrez,  Source	cyclin A2	7999	0.073	0.2184	Yes
21	NUSAP1	NUSAP1 Entrez,  Source	nucleolar and spindle associated protein 1	8179	0.071	0.2285	Yes
22	TMPO	TMPO Entrez,  Source	thymopoietin	8207	0.070	0.2443	Yes
23	MELK	MELK Entrez,  Source	maternal embryonic leucine zipper kinase	8236	0.069	0.2600	Yes
24	DLGAP5			8319	0.068	0.2733	Yes
25	SMC2	SMC2 Entrez,  Source	structural maintenance of chromosomes 2	8352	0.067	0.2883	Yes
26	PAXIP1	PAXIP1 Entrez,  Source	PAX interacting (with transcription-activation domain) protein 1	8356	0.067	0.3043	Yes
27	CDCA8	CDCA8 Entrez,  Source	cell division cycle associated 8	8511	0.064	0.3138	Yes
28	CDK1			8548	0.063	0.3277	Yes
29	TPX2	TPX2 Entrez,  Source	TPX2, microtubule-associated, homolog (Xenopus laevis)	8581	0.062	0.3415	Yes
30	MCM4	MCM4 Entrez,  Source	MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)	8582	0.062	0.3565	Yes
31	DNAJC9	DNAJC9 Entrez,  Source	DnaJ (Hsp40) homolog, subfamily C, member 9	8623	0.061	0.3698	Yes
32	KIF18B			8919	0.060	0.3728	Yes
33	MCM5	MCM5 Entrez,  Source	MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	9075	0.057	0.3806	Yes
34	HNRNPAB			9112	0.056	0.3927	Yes
35	RRM1	RRM1 Entrez,  Source	ribonucleotide reductase M1 polypeptide	9137	0.056	0.4053	Yes
36	HMMR	HMMR Entrez,  Source	hyaluronan-mediated motility receptor (RHAMM)	9173	0.055	0.4173	Yes
37	RACGAP1	RACGAP1 Entrez,  Source	Rac GTPase activating protein 1	9253	0.055	0.4274	Yes
38	TOP2A	TOP2A Entrez,  Source	topoisomerase (DNA) II alpha 170kDa	9270	0.054	0.4399	Yes
39	CCNB2	CCNB2 Entrez,  Source	cyclin B2	9453	0.051	0.4452	Yes
40	MSH2	MSH2 Entrez,  Source	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)	9516	0.050	0.4549	Yes
41	CENPE	CENPE Entrez,  Source	centromere protein E, 312kDa	9548	0.050	0.4658	Yes
42	MCM3	MCM3 Entrez,  Source	MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)	9611	0.049	0.4752	Yes
43	KIF11	KIF11 Entrez,  Source	kinesin family member 11	9652	0.048	0.4853	Yes
44	ASPM	ASPM Entrez,  Source	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	9711	0.047	0.4945	Yes
45	FANCI	FANCI Entrez,  Source	Fanconi anemia, complementation group I	9924	0.045	0.4971	Yes
46	MCM7	MCM7 Entrez,  Source	MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)	9993	0.044	0.5050	Yes
47	HMGB2	HMGB2 Entrez,  Source	high-mobility group box 2	10107	0.042	0.5108	Yes
48	MYBL2	MYBL2 Entrez,  Source	v-myb myeloblastosis viral oncogene homolog (avian)-like 2	10368	0.039	0.5101	Yes
49	BUB1B	BUB1B Entrez,  Source	BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)	10437	0.037	0.5165	Yes
50	MCM2	MCM2 Entrez,  Source	MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)	10680	0.034	0.5154	Yes
51	PCNA	PCNA Entrez,  Source	proliferating cell nuclear antigen	10939	0.031	0.5129	Yes
52	CDC20	CDC20 Entrez,  Source	CDC20 cell division cycle 20 homolog (S. cerevisiae)	10950	0.031	0.5200	Yes
53	PA2G4	PA2G4 Entrez,  Source	proliferation-associated 2G4, 38kDa	11100	0.029	0.5213	Yes
54	RRM2	RRM2 Entrez,  Source	ribonucleotide reductase M2 polypeptide	11196	0.028	0.5245	Yes
55	WHSC1	WHSC1 Entrez,  Source	Wolf-Hirschhorn syndrome candidate 1	11405	0.026	0.5226	No
56	PRC1	PRC1 Entrez,  Source	protein regulator of cytokinesis 1	11666	0.023	0.5181	No
57	ESPL1	ESPL1 Entrez,  Source	extra spindle poles like 1 (S. cerevisiae)	11672	0.023	0.5234	No
58	FOXM1	FOXM1 Entrez,  Source	forkhead box M1	11822	0.021	0.5227	No
59	CKS2	CKS2 Entrez,  Source	CDC28 protein kinase regulatory subunit 2	12217	0.016	0.5113	No
60	FEN1	FEN1 Entrez,  Source	flap structure-specific endonuclease 1	12646	0.011	0.4973	No
61	CENPF	CENPF Entrez,  Source	centromere protein F, 350/400ka (mitosin)	13466	0.001	0.4659	No
62	H2AFX	H2AFX Entrez,  Source	H2A histone family, member X	14049	-0.006	0.4447	No
63	ZWINT	ZWINT Entrez,  Source	ZW10 interactor	14235	-0.008	0.4396	No
64	GINS2	GINS2 Entrez,  Source	GINS complex subunit 2 (Psf2 homolog)	14397	-0.011	0.4359	No
65	RAD54L	RAD54L Entrez,  Source	RAD54-like (S. cerevisiae)	14784	-0.016	0.4249	No
66	MKI67	MKI67 Entrez,  Source	antigen identified by monoclonal antibody Ki-67	15149	-0.022	0.4161	No

Fig 2: GNF2_PCNA   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: GNF2_PCNA: Random ES distribution   
Gene set null distribution of ES for GNF2_PCNA