Details for gene set GNF2

Table: GSEA Results Summary

Dataset	SMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls #del_versus_fl.SMCHD1_KO.cls #del_versus_fl_repos
Phenotype	SMCHD1_KO.cls#del_versus_fl_repos
Upregulated in class	0
GeneSet	GNF2_RFC4
Enrichment Score (ES)	0.5527417
Normalized Enrichment Score (NES)	1.8600888
Nominal p-value	0.0
FDR q-value	0.2461892
FWER p-Value	0.88

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GINS1	GINS1 Entrez, Source	GINS complex subunit 1 (Psf1 homolog)	1800	0.195	-0.0201	Yes
2	RPA3	RPA3 Entrez, Source	replication protein A3, 14kDa	1886	0.184	0.0236	Yes
3	TYMS	TYMS Entrez, Source	thymidylate synthetase	2505	0.150	0.0380	Yes
4	RAD51AP1	RAD51AP1 Entrez, Source	RAD51 associated protein 1	2626	0.146	0.0706	Yes
5	SNRPE	SNRPE Entrez, Source	small nuclear ribonucleoprotein polypeptide E	2669	0.144	0.1056	Yes
6	CKS1B	CKS1B Entrez, Source	CDC28 protein kinase regulatory subunit 1B	2942	0.125	0.1271	Yes
7	NDC80			3031	0.120	0.1542	Yes
8	TTK	TTK Entrez, Source	TTK protein kinase	3042	0.119	0.1841	Yes
9	PLK4	PLK4 Entrez, Source	polo-like kinase 4 (Drosophila)	3251	0.108	0.2035	Yes
10	PRIM1	PRIM1 Entrez, Source	primase, polypeptide 1, 49kDa	3268	0.107	0.2301	Yes
11	RFC4	RFC4 Entrez, Source	replication factor C (activator 1) 4, 37kDa	3299	0.105	0.2557	Yes
12	TIMELESS	TIMELESS Entrez, Source	timeless homolog (Drosophila)	3361	0.102	0.2794	Yes
13	GMNN	GMNN Entrez, Source	geminin, DNA replication inhibitor	3370	0.102	0.3051	Yes
14	DKC1	DKC1 Entrez, Source	dyskeratosis congenita 1, dyskerin	3456	0.098	0.3269	Yes
15	MCM10	MCM10 Entrez, Source	MCM10 minichromosome maintenance deficient 10 (S. cerevisiae)	3508	0.097	0.3496	Yes
16	BIRC5	BIRC5 Entrez, Source	baculoviral IAP repeat-containing 5 (survivin)	3691	0.090	0.3654	Yes
17	SMC4	SMC4 Entrez, Source	structural maintenance of chromosomes 4	3717	0.088	0.3869	Yes
18	MCM6	MCM6 Entrez, Source	MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)	4276	0.076	0.3847	Yes
19	SLBP	SLBP Entrez, Source	stem-loop (histone) binding protein	7995	0.073	0.2595	Yes
20	CCNA2	CCNA2 Entrez, Source	cyclin A2	7999	0.073	0.2780	Yes
21	UBE2C	UBE2C Entrez, Source	ubiquitin-conjugating enzyme E2C	8018	0.072	0.2958	Yes
22	SMC2	SMC2 Entrez, Source	structural maintenance of chromosomes 2	8352	0.067	0.3000	Yes
23	KNTC1	KNTC1 Entrez, Source	kinetochore associated 1	8354	0.067	0.3171	Yes
24	CDK1			8548	0.063	0.3256	Yes
25	MCM4	MCM4 Entrez, Source	MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)	8582	0.062	0.3402	Yes
26	LIG1	LIG1 Entrez, Source	ligase I, DNA, ATP-dependent	8928	0.059	0.3420	Yes
27	RANBP1	RANBP1 Entrez, Source	RAN binding protein 1	9100	0.057	0.3498	Yes
28	SNRPD1	SNRPD1 Entrez, Source	small nuclear ribonucleoprotein D1 polypeptide 16kDa	9105	0.056	0.3640	Yes
29	RRM1	RRM1 Entrez, Source	ribonucleotide reductase M1 polypeptide	9137	0.056	0.3770	Yes
30	CCT2	CCT2 Entrez, Source	chaperonin containing TCP1, subunit 2 (beta)	9162	0.055	0.3901	Yes
31	TOP2A	TOP2A Entrez, Source	topoisomerase (DNA) II alpha 170kDa	9270	0.054	0.3998	Yes
32	PAICS	PAICS Entrez, Source	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	9343	0.053	0.4105	Yes
33	MLH1	MLH1 Entrez, Source	mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)	9347	0.053	0.4238	Yes
34	SSRP1	SSRP1 Entrez, Source	structure specific recognition protein 1	9429	0.052	0.4338	Yes
35	CCNB2	CCNB2 Entrez, Source	cyclin B2	9453	0.051	0.4459	Yes
36	SUPT16H	SUPT16H Entrez, Source	suppressor of Ty 16 homolog (S. cerevisiae)	9506	0.050	0.4568	Yes
37	MSH2	MSH2 Entrez, Source	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)	9516	0.050	0.4692	Yes
38	MCM3	MCM3 Entrez, Source	MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)	9611	0.049	0.4780	Yes
39	KIF11	KIF11 Entrez, Source	kinesin family member 11	9652	0.048	0.4888	Yes
40	ASPM	ASPM Entrez, Source	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	9711	0.047	0.4986	Yes
41	H2AFZ	H2AFZ Entrez, Source	H2A histone family, member Z	9766	0.047	0.5084	Yes
42	FANCI	FANCI Entrez, Source	Fanconi anemia, complementation group I	9924	0.045	0.5137	Yes
43	MCM7	MCM7 Entrez, Source	MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)	9993	0.044	0.5222	Yes
44	RAN	RAN Entrez, Source	RAN, member RAS oncogene family	10062	0.043	0.5304	Yes
45	MSH6	MSH6 Entrez, Source	mutS homolog 6 (E. coli)	10395	0.038	0.5272	Yes
46	RFC5	RFC5 Entrez, Source	replication factor C (activator 1) 5, 36.5kDa	10501	0.037	0.5325	Yes
47	MCM2	MCM2 Entrez, Source	MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)	10680	0.034	0.5344	Yes
48	ITGB3BP	ITGB3BP Entrez, Source	integrin beta 3 binding protein (beta3-endonexin)	10829	0.032	0.5369	Yes
49	NCAPD2	NCAPD2 Entrez, Source	non-SMC condensin I complex, subunit D2	10892	0.032	0.5425	Yes
50	PCNA	PCNA Entrez, Source	proliferating cell nuclear antigen	10939	0.031	0.5487	Yes
51	RFC3	RFC3 Entrez, Source	replication factor C (activator 1) 3, 38kDa	11033	0.030	0.5527	Yes
52	FOXM1	FOXM1 Entrez, Source	forkhead box M1	11822	0.021	0.5276	No
53	CKS2	CKS2 Entrez, Source	CDC28 protein kinase regulatory subunit 2	12217	0.016	0.5164	No
54	FEN1	FEN1 Entrez, Source	flap structure-specific endonuclease 1	12646	0.011	0.5026	No
55	CTPS	CTPS Entrez, Source	CTP synthase	13296	0.003	0.4783	No
56	CENPF	CENPF Entrez, Source	centromere protein F, 350/400ka (mitosin)	13466	0.001	0.4720	No
57	ZWINT	ZWINT Entrez, Source	ZW10 interactor	14235	-0.008	0.4444	No
58	GINS2	GINS2 Entrez, Source	GINS complex subunit 2 (Psf2 homolog)	14397	-0.011	0.4409	No
59	RAD54L	RAD54L Entrez, Source	RAD54-like (S. cerevisiae)	14784	-0.016	0.4301	No