Details for gene set GNF2

Table: GSEA Results Summary

Dataset	SMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls #del_versus_fl.SMCHD1_KO.cls #del_versus_fl_repos
Phenotype	SMCHD1_KO.cls#del_versus_fl_repos
Upregulated in class	0
GeneSet	GNF2_RRM1
Enrichment Score (ES)	0.51715535
Normalized Enrichment Score (NES)	2.0112667
Nominal p-value	0.0
FDR q-value	0.17180802
FWER p-Value	0.338

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NUP37	NUP37 Entrez, Source	nucleoporin 37kDa	1689	0.206	-0.0254	Yes
2	GINS1	GINS1 Entrez, Source	GINS complex subunit 1 (Psf1 homolog)	1800	0.195	0.0081	Yes
3	TYMS	TYMS Entrez, Source	thymidylate synthetase	2505	0.150	0.0101	Yes
4	RAD51AP1	RAD51AP1 Entrez, Source	RAD51 associated protein 1	2626	0.146	0.0339	Yes
5	SNRPG	SNRPG Entrez, Source	small nuclear ribonucleoprotein polypeptide G	2980	0.123	0.0441	Yes
6	NDC80			3031	0.120	0.0655	Yes
7	TTK	TTK Entrez, Source	TTK protein kinase	3042	0.119	0.0882	Yes
8	DHFR	DHFR Entrez, Source	dihydrofolate reductase	3124	0.114	0.1073	Yes
9	SHCBP1	SHCBP1 Entrez, Source	SHC SH2-domain binding protein 1	3202	0.110	0.1257	Yes
10	PLK4	PLK4 Entrez, Source	polo-like kinase 4 (Drosophila)	3251	0.108	0.1448	Yes
11	PRIM1	PRIM1 Entrez, Source	primase, polypeptide 1, 49kDa	3268	0.107	0.1649	Yes
12	RFC4	RFC4 Entrez, Source	replication factor C (activator 1) 4, 37kDa	3299	0.105	0.1842	Yes
13	GMNN	GMNN Entrez, Source	geminin, DNA replication inhibitor	3370	0.102	0.2013	Yes
14	VRK1	VRK1 Entrez, Source	vaccinia related kinase 1	3639	0.091	0.2086	Yes
15	BIRC5	BIRC5 Entrez, Source	baculoviral IAP repeat-containing 5 (survivin)	3691	0.090	0.2241	Yes
16	DTL	DTL Entrez, Source	denticleless homolog (Drosophila)	3696	0.089	0.2412	Yes
17	SMC4	SMC4 Entrez, Source	structural maintenance of chromosomes 4	3717	0.088	0.2576	Yes
18	AURKA	AURKA Entrez, Source	aurora kinase A	3750	0.087	0.2733	Yes
19	MCM6	MCM6 Entrez, Source	MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)	4276	0.076	0.2677	Yes
20	HAT1	HAT1 Entrez, Source	histone acetyltransferase 1	4293	0.075	0.2818	Yes
21	DTYMK	DTYMK Entrez, Source	deoxythymidylate kinase (thymidylate kinase)	4302	0.075	0.2961	Yes
22	SLBP	SLBP Entrez, Source	stem-loop (histone) binding protein	7995	0.073	0.1673	Yes
23	CCNA2	CCNA2 Entrez, Source	cyclin A2	7999	0.073	0.1814	Yes
24	E2F8	E2F8 Entrez, Source	E2F transcription factor 8	8004	0.073	0.1955	Yes
25	UBE2C	UBE2C Entrez, Source	ubiquitin-conjugating enzyme E2C	8018	0.072	0.2091	Yes
26	NUSAP1	NUSAP1 Entrez, Source	nucleolar and spindle associated protein 1	8179	0.071	0.2166	Yes
27	TMPO	TMPO Entrez, Source	thymopoietin	8207	0.070	0.2291	Yes
28	MELK	MELK Entrez, Source	maternal embryonic leucine zipper kinase	8236	0.069	0.2415	Yes
29	DLGAP5			8319	0.068	0.2515	Yes
30	CCT6A	CCT6A Entrez, Source	chaperonin containing TCP1, subunit 6A (zeta 1)	8349	0.067	0.2634	Yes
31	SMC2	SMC2 Entrez, Source	structural maintenance of chromosomes 2	8352	0.067	0.2764	Yes
32	CDCA8	CDCA8 Entrez, Source	cell division cycle associated 8	8511	0.064	0.2827	Yes
33	CDK1			8548	0.063	0.2935	Yes
34	MCM4	MCM4 Entrez, Source	MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)	8582	0.062	0.3043	Yes
35	ANP32E	ANP32E Entrez, Source	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	8593	0.062	0.3160	Yes
36	KIF14	KIF14 Entrez, Source	kinesin family member 14	8695	0.060	0.3237	Yes
37	KIF18B			8919	0.060	0.3267	Yes
38	MCM5	MCM5 Entrez, Source	MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	9075	0.057	0.3317	Yes
39	SNRPD1	SNRPD1 Entrez, Source	small nuclear ribonucleoprotein D1 polypeptide 16kDa	9105	0.056	0.3416	Yes
40	HNRNPAB			9112	0.056	0.3522	Yes
41	RRM1	RRM1 Entrez, Source	ribonucleotide reductase M1 polypeptide	9137	0.056	0.3621	Yes
42	HMMR	HMMR Entrez, Source	hyaluronan-mediated motility receptor (RHAMM)	9173	0.055	0.3715	Yes
43	RACGAP1	RACGAP1 Entrez, Source	Rac GTPase activating protein 1	9253	0.055	0.3790	Yes
44	TOP2A	TOP2A Entrez, Source	topoisomerase (DNA) II alpha 170kDa	9270	0.054	0.3889	Yes
45	PAICS	PAICS Entrez, Source	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	9343	0.053	0.3964	Yes
46	SSRP1	SSRP1 Entrez, Source	structure specific recognition protein 1	9429	0.052	0.4031	Yes
47	CCNB2	CCNB2 Entrez, Source	cyclin B2	9453	0.051	0.4122	Yes
48	MSH2	MSH2 Entrez, Source	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)	9516	0.050	0.4195	Yes
49	CENPE	CENPE Entrez, Source	centromere protein E, 312kDa	9548	0.050	0.4280	Yes
50	MCM3	MCM3 Entrez, Source	MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)	9611	0.049	0.4351	Yes
51	KIF11	KIF11 Entrez, Source	kinesin family member 11	9652	0.048	0.4429	Yes
52	ASPM	ASPM Entrez, Source	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	9711	0.047	0.4499	Yes
53	AURKB	AURKB Entrez, Source	aurora kinase B	9747	0.047	0.4576	Yes
54	NASP	NASP Entrez, Source	nuclear autoantigenic sperm protein (histone-binding)	9757	0.047	0.4664	Yes
55	MRPL35	MRPL35 Entrez, Source	mitochondrial ribosomal protein L35	9864	0.046	0.4711	Yes
56	FANCI	FANCI Entrez, Source	Fanconi anemia, complementation group I	9924	0.045	0.4775	Yes
57	MCM7	MCM7 Entrez, Source	MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)	9993	0.044	0.4833	Yes
58	RAN	RAN Entrez, Source	RAN, member RAS oncogene family	10062	0.043	0.4890	Yes
59	HMGB2	HMGB2 Entrez, Source	high-mobility group box 2	10107	0.042	0.4955	Yes
60	TCP1	TCP1 Entrez, Source	t-complex 1	10156	0.041	0.5016	Yes
61	BUB1B	BUB1B Entrez, Source	BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)	10437	0.037	0.4981	Yes
62	MCM2	MCM2 Entrez, Source	MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)	10680	0.034	0.4954	Yes
63	SERBP1	SERBP1 Entrez, Source	SERPINE1 mRNA binding protein 1	10765	0.033	0.4986	Yes
64	PCNA	PCNA Entrez, Source	proliferating cell nuclear antigen	10939	0.031	0.4979	Yes
65	USP14	USP14 Entrez, Source	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	10945	0.031	0.5037	Yes
66	CDC20	CDC20 Entrez, Source	CDC20 cell division cycle 20 homolog (S. cerevisiae)	10950	0.031	0.5095	Yes
67	RFC3	RFC3 Entrez, Source	replication factor C (activator 1) 3, 38kDa	11033	0.030	0.5122	Yes
68	PA2G4	PA2G4 Entrez, Source	proliferation-associated 2G4, 38kDa	11100	0.029	0.5153	Yes
69	RRM2	RRM2 Entrez, Source	ribonucleotide reductase M2 polypeptide	11196	0.028	0.5172	Yes
70	EIF2S1	EIF2S1 Entrez, Source	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	11375	0.026	0.5153	No
71	PRC1	PRC1 Entrez, Source	protein regulator of cytokinesis 1	11666	0.023	0.5085	No
72	FOXM1	FOXM1 Entrez, Source	forkhead box M1	11822	0.021	0.5066	No
73	METAP2	METAP2 Entrez, Source	methionyl aminopeptidase 2	11990	0.019	0.5038	No
74	PTGES3	PTGES3 Entrez, Source	prostaglandin E synthase 3 (cytosolic)	12195	0.016	0.4991	No
75	CKS2	CKS2 Entrez, Source	CDC28 protein kinase regulatory subunit 2	12217	0.016	0.5014	No
76	CENPM	CENPM Entrez, Source	centromere protein M	12220	0.016	0.5044	No
77	PSMD14	PSMD14 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	12396	0.014	0.5003	No
78	FEN1	FEN1 Entrez, Source	flap structure-specific endonuclease 1	12646	0.011	0.4928	No
79	CENPF	CENPF Entrez, Source	centromere protein F, 350/400ka (mitosin)	13466	0.001	0.4612	No
80	CHCHD3	CHCHD3 Entrez, Source	coiled-coil-helix-coiled-coil-helix domain containing 3	13714	-0.002	0.4520	No
81	H2AFX	H2AFX Entrez, Source	H2A histone family, member X	14049	-0.006	0.4402	No
82	ZWINT	ZWINT Entrez, Source	ZW10 interactor	14235	-0.008	0.4347	No
83	GINS2	GINS2 Entrez, Source	GINS complex subunit 2 (Psf2 homolog)	14397	-0.011	0.4305	No
84	MKI67	MKI67 Entrez, Source	antigen identified by monoclonal antibody Ki-67	15149	-0.022	0.4057	No
85	PCCB	PCCB Entrez, Source	propionyl Coenzyme A carboxylase, beta polypeptide	17337	-0.055	0.3316	No