Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | SMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls #del_versus_fl.SMCHD1_KO.cls #del_versus_fl_repos |
| Phenotype | SMCHD1_KO.cls#del_versus_fl_repos |
| Upregulated in class | 0 |
| GeneSet | GO_DNA_DEPENDENT_DNA_REPLICATION_MAINTENANCE_OF_FIDELITY |
| Enrichment Score (ES) | 0.6268301 |
| Normalized Enrichment Score (NES) | 1.8337617 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.24561277 |
| FWER p-Value | 0.939 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SETMAR | SETMAR Entrez, Source | SET domain and mariner transposase fusion gene | 28 | 1.113 | 0.4966 | Yes |
| 2 | MMS22L | 3118 | 0.115 | 0.4285 | Yes | ||
| 3 | TIPIN | TIPIN Entrez, Source | TIMELESS interacting protein | 3139 | 0.114 | 0.4786 | Yes |
| 4 | APITD1 | APITD1 Entrez, Source | apoptosis-inducing, TAF9-like domain 1 | 3280 | 0.106 | 0.5206 | Yes |
| 5 | BLM | BLM Entrez, Source | Bloom syndrome | 3626 | 0.092 | 0.5484 | Yes |
| 6 | CCDC111 | CCDC111 Entrez, Source | coiled-coil domain containing 111 | 4041 | 0.084 | 0.5699 | Yes |
| 7 | THOC1 | THOC1 Entrez, Source | THO complex 1 | 4222 | 0.078 | 0.5977 | Yes |
| 8 | RAD51 | RAD51 Entrez, Source | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 4332 | 0.074 | 0.6268 | Yes |
| 9 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 9097 | 0.057 | 0.4680 | No |
| 10 | WRN | WRN Entrez, Source | Werner syndrome | 9325 | 0.053 | 0.4830 | No |
| 11 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10086 | 0.042 | 0.4726 | No |
| 12 | ZRANB3 | ZRANB3 Entrez, Source | zinc finger, RAN-binding domain containing 3 | 10264 | 0.040 | 0.4836 | No |
| 13 | RTEL1 | RTEL1 Entrez, Source | regulator of telomere elongation helicase 1 | 10873 | 0.032 | 0.4743 | No |
| 14 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10939 | 0.031 | 0.4857 | No |
| 15 | FANCM | FANCM Entrez, Source | Fanconi anemia, complementation group M | 11189 | 0.028 | 0.4887 | No |
| 16 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 12535 | 0.012 | 0.4422 | No |
| 17 | CDK9 | CDK9 Entrez, Source | cyclin-dependent kinase 9 (CDC2-related kinase) | 14946 | -0.019 | 0.3574 | No |
| 18 | BOD1L | 15249 | -0.023 | 0.3561 | No | ||
| 19 | TONSL | 15528 | -0.026 | 0.3572 | No | ||
| 20 | STRA13 | STRA13 Entrez, Source | stimulated by retinoic acid 13 homolog (mouse) | 15538 | -0.027 | 0.3689 | No |
| 21 | SMARCAL1 | SMARCAL1 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 | 15906 | -0.032 | 0.3692 | No |
| 22 | FBXO18 | FBXO18 Entrez, Source | F-box protein, helicase, 18 | 16415 | -0.038 | 0.3665 | No |
