DatasetSMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls
#del_versus_fl.SMCHD1_KO.cls
#del_versus_fl_repos
PhenotypeSMCHD1_KO.cls#del_versus_fl_repos
Upregulated in class0
GeneSetGO_DNA_DOUBLE_STRAND_BREAK_PROCESSING
Enrichment Score (ES)0.6479427
Normalized Enrichment Score (NES)1.8115509
Nominal p-value0.0053475937
FDR q-value0.2359882
FWER p-Value0.978
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO_DNA_DOUBLE_STRAND_BREAK_PROCESSING   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SETMARSETMAR
Entrez,  Source
SET domain and mariner transposase fusion gene281.1130.5266Yes
2RAD50RAD50
Entrez,  Source
RAD50 homolog (S. cerevisiae)28330.1330.4812Yes
3BARD1BARD1
Entrez,  Source
BRCA1 associated RING domain 131460.1130.5229Yes
4RAD52RAD52
Entrez,  Source
RAD52 homolog (S. cerevisiae)33240.1040.5654Yes
5BLMBLM
Entrez,  Source
Bloom syndrome36260.0920.5973Yes
6SMARCAD1SMARCAD1
Entrez,  Source
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 140830.0830.6189Yes
7NBNNBN
Entrez,  Source
nibrin42680.0760.6479Yes
8RBBP8RBBP8
Entrez,  Source
retinoblastoma binding protein 881780.0710.5304No
9BRCA1BRCA1
Entrez,  Source
breast cancer 1, early onset85410.0630.5463No
10RNF138RNF138
Entrez,  Source
ring finger protein 13895090.0500.5328No
11DNA2107470.0330.5009No
12UBE2V2UBE2V2
Entrez,  Source
ubiquitin-conjugating enzyme E2 variant 2108710.0320.5112No
13MRE11AMRE11A
Entrez,  Source
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)112140.0280.5113No
14KAT5118170.0210.4980No
15UBE2NUBE2N
Entrez,  Source
ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)121870.0160.4916No
16EXD2126160.0110.4804No
17SLX1B13841-0.0030.4347No
18SLX413997-0.0050.4312No
19ATMATM
Entrez,  Source
ataxia telangiectasia mutated (includes complementation groups A, C and D)17577-0.0600.3215No
Table: GSEA details [plain text format]



Fig 2: GO_DNA_DOUBLE_STRAND_BREAK_PROCESSING   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO_DNA_DOUBLE_STRAND_BREAK_PROCESSING: Random ES distribution   
Gene set null distribution of ES for GO_DNA_DOUBLE_STRAND_BREAK_PROCESSING