Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | SMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls #del_versus_fl.SMCHD1_KO.cls #del_versus_fl_repos |
| Phenotype | SMCHD1_KO.cls#del_versus_fl_repos |
| Upregulated in class | 1 |
| GeneSet | MOSERLE_IFNA_RESPONSE |
| Enrichment Score (ES) | -0.8847192 |
| Normalized Enrichment Score (NES) | -1.8746923 |
| Nominal p-value | 0.0 |
| FDR q-value | 7.0577E-5 |
| FWER p-Value | 0.002 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IFITM1 | IFITM1 Entrez, Source | interferon induced transmembrane protein 1 (9-27) | 995 | 0.299 | -0.0281 | No |
| 2 | TNFSF10 | TNFSF10 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 10 | 10244 | 0.040 | -0.3841 | No |
| 3 | GBP1 | GBP1 Entrez, Source | guanylate binding protein 1, interferon-inducible, 67kDa | 10631 | 0.035 | -0.3979 | No |
| 4 | ZC3HAV1 | ZC3HAV1 Entrez, Source | zinc finger CCCH-type, antiviral 1 | 15792 | -0.031 | -0.5962 | No |
| 5 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 23259 | -0.399 | -0.8710 | Yes |
| 6 | CMPK2 | 23278 | -0.403 | -0.8578 | Yes | ||
| 7 | EPSTI1 | EPSTI1 Entrez, Source | epithelial stromal interaction 1 (breast) | 23538 | -0.439 | -0.8527 | Yes |
| 8 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 23939 | -0.510 | -0.8506 | Yes |
| 9 | DDX58 | DDX58 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 24122 | -0.545 | -0.8388 | Yes |
| 10 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 24672 | -0.695 | -0.8361 | Yes |
| 11 | CD274 | CD274 Entrez, Source | CD274 molecule | 25335 | -1.036 | -0.8259 | Yes |
| 12 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 25437 | -1.129 | -0.7909 | Yes |
| 13 | OAS2 | OAS2 Entrez, Source | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 25558 | -1.284 | -0.7514 | Yes |
| 14 | DDX60 | 25710 | -1.643 | -0.7006 | Yes | ||
| 15 | RSAD2 | RSAD2 Entrez, Source | radical S-adenosyl methionine domain containing 2 | 25795 | -2.013 | -0.6345 | Yes |
| 16 | IFIH1 | IFIH1 Entrez, Source | interferon induced with helicase C domain 1 | 25804 | -2.052 | -0.5641 | Yes |
| 17 | USP18 | USP18 Entrez, Source | ubiquitin specific peptidase 18 | 25830 | -2.231 | -0.4882 | Yes |
| 18 | IFI44 | IFI44 Entrez, Source | interferon-induced protein 44 | 25831 | -2.278 | -0.4097 | Yes |
| 19 | RTP4 | RTP4 Entrez, Source | receptor transporter protein 4 | 25833 | -2.300 | -0.3305 | Yes |
| 20 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 25844 | -2.414 | -0.2478 | Yes |
| 21 | SAMD9L | SAMD9L Entrez, Source | sterile alpha motif domain containing 9-like | 25888 | -3.178 | -0.1399 | Yes |
| 22 | IFIT1 | IFIT1 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 1 | 25894 | -4.073 | 0.0002 | Yes |
