Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | SMCHD1_KO_collapsed_to_symbols.SMCHD1_KO.cls #del_versus_fl.SMCHD1_KO.cls #del_versus_fl_repos |
| Phenotype | SMCHD1_KO.cls#del_versus_fl_repos |
| Upregulated in class | 1 |
| GeneSet | XU_AKT1_TARGETS_6HR |
| Enrichment Score (ES) | -0.88921374 |
| Normalized Enrichment Score (NES) | -1.8958249 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.6594196E-5 |
| FWER p-Value | 0.001 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | INHBC | INHBC Entrez, Source | inhibin, beta C | 448 | 0.446 | 0.0131 | No |
| 2 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 8541 | 0.063 | -0.2953 | No |
| 3 | CDC5L | CDC5L Entrez, Source | CDC5 cell division cycle 5-like (S. pombe) | 8587 | 0.062 | -0.2928 | No |
| 4 | OAS3 | OAS3 Entrez, Source | 2'-5'-oligoadenylate synthetase 3, 100kDa | 9242 | 0.055 | -0.3143 | No |
| 5 | ERF | ERF Entrez, Source | Ets2 repressor factor | 9345 | 0.053 | -0.3147 | No |
| 6 | UBB | UBB Entrez, Source | ubiquitin B | 10499 | 0.037 | -0.3567 | No |
| 7 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 10638 | 0.035 | -0.3597 | No |
| 8 | HNRNPH1 | 11919 | 0.020 | -0.4078 | No | ||
| 9 | MAP2K5 | MAP2K5 Entrez, Source | mitogen-activated protein kinase kinase 5 | 12239 | 0.016 | -0.4191 | No |
| 10 | TAT | TAT Entrez, Source | tyrosine aminotransferase | 14376 | -0.010 | -0.5009 | No |
| 11 | ABI1 | ABI1 Entrez, Source | abl-interactor 1 | 14469 | -0.012 | -0.5037 | No |
| 12 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 14659 | -0.014 | -0.5100 | No |
| 13 | ERBB2IP | ERBB2IP Entrez, Source | erbb2 interacting protein | 15823 | -0.031 | -0.5528 | No |
| 14 | TCTN2 | 16949 | -0.048 | -0.5930 | No | ||
| 15 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 17645 | -0.062 | -0.6157 | No |
| 16 | L3MBTL1 | 18059 | -0.072 | -0.6267 | No | ||
| 17 | IFITM2 | IFITM2 Entrez, Source | interferon induced transmembrane protein 2 (1-8D) | 18119 | -0.074 | -0.6239 | No |
| 18 | PLSCR1 | PLSCR1 Entrez, Source | phospholipid scramblase 1 | 19108 | -0.104 | -0.6550 | No |
| 19 | LYST | LYST Entrez, Source | lysosomal trafficking regulator | 20268 | -0.151 | -0.6895 | No |
| 20 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 25437 | -1.129 | -0.8120 | Yes |
| 21 | ISG15 | ISG15 Entrez, Source | ISG15 ubiquitin-like modifier | 25699 | -1.594 | -0.7132 | Yes |
| 22 | IRF7 | IRF7 Entrez, Source | interferon regulatory factor 7 | 25794 | -2.009 | -0.5796 | Yes |
| 23 | IFIH1 | IFIH1 Entrez, Source | interferon induced with helicase C domain 1 | 25804 | -2.052 | -0.4397 | Yes |
| 24 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 25844 | -2.414 | -0.2763 | Yes |
| 25 | IFIT1 | IFIT1 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 1 | 25894 | -4.073 | 0.0002 | Yes |
