Details for gene set BIOCARTA_EIF4_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	WT
GeneSet	BIOCARTA_EIF4_PATHWAY
Enrichment Score (ES)	-0.3297583
Normalized Enrichment Score (NES)	-1.0437782
Nominal p-value	0.43460765
FDR q-value	0.9860368
FWER p-Value	0.976

Fig 1: Enrichment plot: BIOCARTA_EIF4_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Eif4ebp1	Eif4ebp1	3062	0.512	-0.0459	No
2	Mknk1	Mknk1	4930	0.362	-0.0664	No
3	Eif4a1	Eif4a1	4968	0.359	-0.0145	No
4	Prkcb	Prkcb	4979	0.359	0.0385	No
5	Pten	Pten	5905	0.304	0.0468	No
6	Pdpk1	Pdpk1	5983	0.299	0.0882	No
7	Pik3ca	Pik3ca	7134	0.238	0.0777	No
8	Pabpc1	Pabpc1	7942	0.201	0.0755	No
9	Rps6kb1	Rps6kb1	11027	0.078	-0.0358	No
10	Eif4a2	Eif4a2	13500	-0.009	-0.1330	No
11	Mapk1	Mapk1	18437	-0.197	-0.3005	Yes
12	Mtor	Mtor	18894	-0.217	-0.2864	Yes
13	Mapk3	Mapk3	19068	-0.224	-0.2600	Yes
14	Prkca	Prkca	19435	-0.241	-0.2388	Yes
15	Irs1	Irs1	19600	-0.250	-0.2081	Yes
16	Akt1	Akt1	19946	-0.268	-0.1820	Yes
17	Pik3r1	Pik3r1	20403	-0.293	-0.1567	Yes
18	Eif4e	Eif4e	21820	-0.384	-0.1560	Yes
19	Pdk2	Pdk2	23455	-0.557	-0.1383	Yes
20	Ghr	Ghr	23781	-0.615	-0.0598	Yes
21	Mapk14	Mapk14	24295	-0.757	0.0324	Yes

Fig 2: BIOCARTA_EIF4_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_EIF4_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_EIF4_PATHWAY