Details for gene set BIOCARTA_ERK_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	KO
GeneSet	BIOCARTA_ERK_PATHWAY
Enrichment Score (ES)	0.35787657
Normalized Enrichment Score (NES)	1.2609468
Nominal p-value	0.19421488
FDR q-value	0.670244
FWER p-Value	0.897

Fig 1: Enrichment plot: BIOCARTA_ERK_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Myc	Myc	211	1.433	0.1743	Yes
2	Ngfr	Ngfr	289	1.314	0.3388	Yes
3	Pdgfra	Pdgfra	3001	0.518	0.2968	Yes
4	Rps6ka1	Rps6ka1	4565	0.387	0.2838	Yes
5	Mknk1	Mknk1	4930	0.362	0.3155	Yes
6	Mknk2	Mknk2	5007	0.356	0.3579	Yes
7	Egfr	Egfr	8592	0.174	0.2372	No
8	Sos1	Sos1	9483	0.139	0.2194	No
9	Igf1r	Igf1r	10752	0.089	0.1802	No
10	Shc1	Shc1	11228	0.071	0.1703	No
11	Gnas	Gnas	11478	0.062	0.1683	No
12	Ngf	Ngf	11996	0.044	0.1533	No
13	Itgb1	Itgb1	13671	-0.015	0.0885	No
14	Elk1	Elk1	14138	-0.032	0.0740	No
15	Map2k1	Map2k1	14564	-0.047	0.0631	No
16	Hras	Hras	15263	-0.073	0.0446	No
17	Ppp2ca	Ppp2ca	15419	-0.078	0.0483	No
18	Grb2	Grb2	17172	-0.143	-0.0033	No
19	Mapk1	Mapk1	18437	-0.197	-0.0286	No
20	Ptprr	Ptprr	18472	-0.199	-0.0046	No
21	Mapk3	Mapk3	19068	-0.224	0.0003	No
22	Map2k2	Map2k2	19750	-0.258	0.0060	No
23	Stat3	Stat3	21544	-0.364	-0.0191	No
24	Raf1	Raf1	22482	-0.440	-0.0004	No
25	Rps6ka5	Rps6ka5	24479	-0.824	0.0250	No

Fig 2: BIOCARTA_ERK_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_ERK_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_ERK_PATHWAY