Details for gene set BIOCARTA_IL2_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	WT
GeneSet	BIOCARTA_IL2_PATHWAY
Enrichment Score (ES)	-0.26160735
Normalized Enrichment Score (NES)	-1.0077468
Nominal p-value	0.45614034
FDR q-value	0.9848752
FWER p-Value	0.981

Fig 1: Enrichment plot: BIOCARTA_IL2_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Syk	Syk	1062	0.847	0.0853	No
2	Jun	Jun	2818	0.539	0.0966	No
3	Lck	Lck	2978	0.520	0.1686	No
4	Il2rb	Il2rb	4269	0.408	0.1787	No
5	Fos	Fos	8808	0.166	0.0228	No
6	Sos1	Sos1	9483	0.139	0.0168	No
7	Shc1	Shc1	11228	0.071	-0.0420	No
8	Jak3	Jak3	11311	0.068	-0.0351	No
9	Elk1	Elk1	14138	-0.032	-0.1429	No
10	Map2k1	Map2k1	14564	-0.047	-0.1527	No
11	Hras	Hras	15263	-0.073	-0.1696	No
12	Csnk2a2	Csnk2a2	16082	-0.102	-0.1868	No
13	Grb2	Grb2	17172	-0.143	-0.2086	No
14	Il2rg	Il2rg	17328	-0.149	-0.1923	No
15	Mapk3	Mapk3	19068	-0.224	-0.2278	Yes
16	Mapk8	Mapk8	19234	-0.232	-0.1995	Yes
17	Csnk2a1	Csnk2a1	20343	-0.289	-0.2001	Yes
18	Stat5a	Stat5a	20939	-0.322	-0.1753	Yes
19	Raf1	Raf1	22482	-0.440	-0.1705	Yes
20	Stat5b	Stat5b	23534	-0.567	-0.1269	Yes
21	Jak1	Jak1	23798	-0.618	-0.0443	Yes
22	Il2ra	Il2ra	23906	-0.640	0.0479	Yes

Fig 2: BIOCARTA_IL2_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_IL2_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_IL2_PATHWAY