Details for gene set BIOCARTA_INSULIN_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	WT
GeneSet	BIOCARTA_INSULIN_PATHWAY
Enrichment Score (ES)	-0.3436456
Normalized Enrichment Score (NES)	-1.0705253
Nominal p-value	0.4055666
FDR q-value	1.0
FWER p-Value	0.974

Fig 1: Enrichment plot: BIOCARTA_INSULIN_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Jun	Jun	2818	0.539	0.0006	No
2	Pik3ca	Pik3ca	7134	0.238	-0.1215	No
3	Pik3cg	Pik3cg	7381	0.227	-0.0837	No
4	Fos	Fos	8808	0.166	-0.1058	No
5	Sos1	Sos1	9483	0.139	-0.1036	No
6	Insr	Insr	10570	0.096	-0.1268	No
7	Shc1	Shc1	11228	0.071	-0.1381	No
8	Srf	Srf	11345	0.067	-0.1287	No
9	Ptpn11	Ptpn11	12607	0.023	-0.1740	No
10	Elk1	Elk1	14138	-0.032	-0.2283	No
11	Map2k1	Map2k1	14564	-0.047	-0.2354	No
12	Hras	Hras	15263	-0.073	-0.2479	No
13	Csnk2a2	Csnk2a2	16082	-0.102	-0.2591	No
14	Grb2	Grb2	17172	-0.143	-0.2725	No
15	Rasa1	Rasa1	18958	-0.219	-0.2977	Yes
16	Mapk3	Mapk3	19068	-0.224	-0.2550	Yes
17	Mapk8	Mapk8	19234	-0.232	-0.2131	Yes
18	Irs1	Irs1	19600	-0.250	-0.1752	Yes
19	Csnk2a1	Csnk2a1	20343	-0.289	-0.1442	Yes
20	Pik3r1	Pik3r1	20403	-0.293	-0.0852	Yes
21	Raf1	Raf1	22482	-0.440	-0.0758	Yes
22	Slc2a4	Slc2a4	24557	-0.860	0.0219	Yes

Fig 2: BIOCARTA_INSULIN_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_INSULIN_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_INSULIN_PATHWAY