Details for gene set BIOCARTA_P53_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	KO
GeneSet	BIOCARTA_P53_PATHWAY
Enrichment Score (ES)	0.4954259
Normalized Enrichment Score (NES)	1.4941471
Nominal p-value	0.024489796
FDR q-value	0.6967153
FWER p-Value	0.626

Fig 1: Enrichment plot: BIOCARTA_P53_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Bcl2	Bcl2	307	1.295	0.2716	Yes
2	Cdkn1a	Cdkn1a	2946	0.523	0.2812	Yes
3	E2f1	E2f1	3364	0.483	0.3704	Yes
4	Apaf1	Apaf1	4244	0.410	0.4252	Yes
5	Mdm2	Mdm2	6351	0.278	0.4023	Yes
6	Ccne1	Ccne1	6414	0.275	0.4600	Yes
7	Bax	Bax	6900	0.250	0.4954	Yes
8	Timp3	Timp3	11355	0.066	0.3325	No
9	Cdk4	Cdk4	11576	0.059	0.3366	No
10	Trp53	Trp53	11872	0.048	0.3354	No
11	Rb1	Rb1	14025	-0.028	0.2557	No
12	Ccnd1	Ccnd1	15281	-0.073	0.2218	No
13	Gadd45a	Gadd45a	16008	-0.099	0.2147	No
14	Pcna	Pcna	17654	-0.162	0.1847	No
15	Cdk2	Cdk2	23131	-0.512	0.0787	No

Fig 2: BIOCARTA_P53_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_P53_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_P53_PATHWAY