Details for gene set REACTOME_HDACS_DEACETYLATE_HISTONES[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	KO
GeneSet	REACTOME_HDACS_DEACETYLATE_HISTONES
Enrichment Score (ES)	0.5081664
Normalized Enrichment Score (NES)	1.7398435
Nominal p-value	0.0
FDR q-value	0.7454094
FWER p-Value	0.73

Fig 1: Enrichment plot: REACTOME_HDACS_DEACETYLATE_HISTONES   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	H3c7	H3c7	587	1.051	0.0211	Yes
2	H2bc8	H2bc8	636	1.025	0.0626	Yes
3	H2bc6	H2bc6	652	1.014	0.1050	Yes
4	H2ac10	H2ac10	724	0.979	0.1437	Yes
5	H2ac6	H2ac6	726	0.979	0.1851	Yes
6	H3c6	H3c6	862	0.927	0.2190	Yes
7	H4c8	H4c8	1258	0.795	0.2370	Yes
8	H4c3	H4c3	1304	0.783	0.2683	Yes
9	H2aj	H2aj	1305	0.782	0.3015	Yes
10	H2bc13	H2bc13	1582	0.716	0.3208	Yes
11	H2ac7	H2ac7	1993	0.649	0.3320	Yes
12	H3c15	H3c15	1998	0.647	0.3593	Yes
13	H3c11	H3c11	2275	0.607	0.3740	Yes
14	H2bc15	H2bc15	2459	0.582	0.3913	Yes
15	H2bc4	H2bc4	2570	0.570	0.4111	Yes
16	H4c4	H4c4	2809	0.540	0.4245	Yes
17	H3c4	H3c4	3131	0.505	0.4331	Yes
18	H4c14	H4c14	3193	0.498	0.4517	Yes
19	H4c1	H4c1	3255	0.492	0.4702	Yes
20	H2bc3	H2bc3	3330	0.486	0.4878	Yes
21	H4c11	H4c11	3463	0.475	0.5027	Yes
22	H4c9	H4c9	3797	0.444	0.5082	Yes
23	H3c8	H3c8	4530	0.389	0.4954	No
24	H2ac25	H2ac25	6168	0.289	0.4423	No
25	H2bc18	H2bc18	6316	0.280	0.4483	No
26	Arid4b	Arid4b	6665	0.261	0.4455	No
27	H2ac8	H2ac8	7131	0.238	0.4370	No
28	H4c6	H4c6	7806	0.208	0.4189	No
29	H2bc26	H2bc26	8106	0.194	0.4152	No
30	H2bc11	H2bc11	8374	0.184	0.4123	No
31	Hdac10	Hdac10	8830	0.165	0.4011	No
32	Mbd3	Mbd3	9313	0.147	0.3881	No
33	H2ac19	H2ac19	9696	0.130	0.3783	No
34	Rest	Rest	10125	0.114	0.3661	No
35	Hdac1	Hdac1	11044	0.078	0.3327	No
36	Phf21a	Phf21a	11177	0.073	0.3305	No
37	Suds3	Suds3	11335	0.067	0.3271	No
38	H3c2	H3c2	11349	0.067	0.3294	No
39	Sap30l	Sap30l	11657	0.055	0.3195	No
40	Arid4a	Arid4a	12580	0.024	0.2837	No
41	Tbl1xr1	Tbl1xr1	12860	0.014	0.2731	No
42	Hmg20b	Hmg20b	13542	-0.011	0.2464	No
43	Kdm1a	Kdm1a	13708	-0.016	0.2405	No
44	H4c12	H4c12	13836	-0.021	0.2363	No
45	Hdac8	Hdac8	13996	-0.027	0.2311	No
46	H4c16	H4c16	14184	-0.034	0.2251	No
47	Rbbp4	Rbbp4	15373	-0.076	0.1809	No
48	Mta2	Mta2	15779	-0.090	0.1685	No
49	Gatad2a	Gatad2a	15797	-0.091	0.1717	No
50	Mta3	Mta3	16075	-0.102	0.1650	No
51	H2bc9	H2bc9	16136	-0.104	0.1670	No
52	Chd4	Chd4	17946	-0.175	0.1022	No
53	Tbl1x	Tbl1x	18952	-0.219	0.0713	No
54	Gps2	Gps2	19154	-0.228	0.0730	No
55	Gatad2b	Gatad2b	19513	-0.244	0.0690	No
56	Rbbp7	Rbbp7	19738	-0.257	0.0710	No
57	Mta1	Mta1	20036	-0.273	0.0707	No
58	H2ac21	H2ac21	20062	-0.274	0.0813	No
59	Rcor1	Rcor1	20539	-0.300	0.0750	No
60	Hdac3	Hdac3	21638	-0.371	0.0469	No
61	Ncor2	Ncor2	22305	-0.423	0.0383	No
62	Sap30	Sap30	22461	-0.437	0.0506	No
63	H2bc21	H2bc21	23472	-0.560	0.0340	No
64	Chd3	Chd3	24239	-0.737	0.0347	No

Fig 2: REACTOME_HDACS_DEACETYLATE_HISTONES   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_HDACS_DEACETYLATE_HISTONES: Random ES distribution   
Gene set null distribution of ES for REACTOME_HDACS_DEACETYLATE_HISTONES