Details for gene set REACTOME_NEUREXINS_AND_NEUROLIGINS[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	KO
GeneSet	REACTOME_NEUREXINS_AND_NEUROLIGINS
Enrichment Score (ES)	0.62361044
Normalized Enrichment Score (NES)	1.7383491
Nominal p-value	0.0
FDR q-value	0.6595093
FWER p-Value	0.732

Fig 1: Enrichment plot: REACTOME_NEUREXINS_AND_NEUROLIGINS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Grm5	Grm5	154	1.575	0.1143	Yes
2	Lrrtm4	Lrrtm4	226	1.417	0.2198	Yes
3	Dlgap3	Dlgap3	525	1.096	0.2918	Yes
4	Sorbs2	Sorbs2	572	1.063	0.3712	Yes
5	Nrxn3	Nrxn3	717	0.982	0.4405	Yes
6	Nlgn4l	Nlgn4l	1342	0.768	0.4743	Yes
7	Dlg2	Dlg2	1668	0.699	0.5148	Yes
8	Shank1	Shank1	1802	0.678	0.5613	Yes
9	Lrrtm3	Lrrtm3	2320	0.601	0.5866	Yes
10	Nrxn1	Nrxn1	2500	0.577	0.6236	Yes
11	Nrxn2	Nrxn2	6303	0.281	0.4935	No
12	Homer3	Homer3	7804	0.208	0.4496	No
13	Nlgn3	Nlgn3	8531	0.177	0.4342	No
14	Dlg4	Dlg4	8744	0.168	0.4386	No
15	Nlgn2	Nlgn2	9244	0.149	0.4301	No
16	Dlgap1	Dlgap1	11127	0.075	0.3607	No
17	Homer1	Homer1	13630	-0.014	0.2620	No
18	Dlg3	Dlg3	16358	-0.112	0.1619	No
19	Epb41l2	Epb41l2	16384	-0.113	0.1695	No
20	Epb41l5	Epb41l5	17718	-0.166	0.1290	No
21	Epb41l3	Epb41l3	17731	-0.166	0.1412	No
22	Cask	Cask	17786	-0.169	0.1520	No
23	Dlgap4	Dlgap4	19579	-0.249	0.0995	No
24	Shank3	Shank3	19818	-0.261	0.1100	No
25	Homer2	Homer2	20814	-0.315	0.0945	No
26	Epb41	Epb41	22416	-0.433	0.0638	No
27	Grm1	Grm1	23545	-0.569	0.0623	No

Fig 2: REACTOME_NEUREXINS_AND_NEUROLIGINS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_NEUREXINS_AND_NEUROLIGINS: Random ES distribution   
Gene set null distribution of ES for REACTOME_NEUREXINS_AND_NEUROLIGINS